Francisco Luís Almeida Paes

ORCID: 0000-0003-3130-4296
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About
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Research Areas
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Molecular Biology Techniques and Applications
  • Colorectal and Anal Carcinomas
  • Protease and Inhibitor Mechanisms
  • Genetic factors in colorectal cancer
  • Peptidase Inhibition and Analysis
  • Metastasis and carcinoma case studies

Universidade Federal de Pernambuco
2021-2025

Matrix metalloproteinases (MMP) have been identified as biomarkers for several diseases, including cancer. The increase in the expression of these enzymes has related to greater tumor aggressiveness. MMP-26 is expressed constitutively endometrium and some cancer cells epithelial origin. However, there a lack studies on its prostatic carcinoma. In this study, evaluation reactivity by immunohistochemistry (IHC) was carried out 150 paraffinized samples representative benign malignant lesions....

10.1590/0001-3765202520231380 article EN cc-by Anais da Academia Brasileira de Ciências 2025-01-01

ABSTRACT Introduction Matrix metalloproteinases (MMP) have been identified as biomarkers for several diseases, including cancer. MMP-26 is constitutively expressed in some cancer cells of epithelial origin. Despite this, there a lack studies regarding the expression on prostatic carcinoma. Aim Here, we investigate peptide benign and malign tissues. Patients Methods For 150 specimens, atrophy (N = 25), intraepithelial neoplasia (PIN) hyperplasia (BPH) 50), adenocarcinoma (PA) were...

10.1101/2021.05.28.21257789 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-05-29
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