- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Hip disorders and treatments
- Advancements in Transdermal Drug Delivery
- Graphene and Nanomaterials Applications
- Bone Metabolism and Diseases
- Natural product bioactivities and synthesis
- Cardiac, Anesthesia and Surgical Outcomes
- Curcumin's Biomedical Applications
- Bone Tissue Engineering Materials
- Advanced Drug Delivery Systems
- Surgical Simulation and Training
- Sexual function and dysfunction studies
- Cardiovascular and exercise physiology
- Hormonal and reproductive studies
- Ethnobotanical and Medicinal Plants Studies
- Radioactive Decay and Measurement Techniques
- Medicinal Plant Research
- Estrogen and related hormone effects
- Flowering Plant Growth and Cultivation
- AI in cancer detection
- Phytochemical and Pharmacological Studies
- Economic and Financial Impacts of Cancer
Nitte University
2021-2024
National Centre for Disease Informatics and Research
2018-2020
University Hospital of Wales
1990-2019
Indian Council of Medical Research
2018
Cardiff and Vale University Health Board
2018
Cardiff University
2013
University Hospital Llandough
2009
The systematic collection of data on cancer is being performed by various population-based registries (PBCRs) and hospital-based (HBCRs) across India under the National Cancer Registry Programme-National Centre for Disease Informatics Research Indian Council Medical since 1982.
Plasma levels of cobalt and chromium ions Metal Artefact Reduction Sequence (MARS)-MRI scans were performed on patients with 209 consecutive, unilateral, symptomatic metal-on-metal (MoM) hip arthroplasties. There was wide variation in plasma levels, MARS-MRI positive for adverse reaction to metal debris (ARMD) 84 hips (40%). a significant difference the median between those negative (p < 0.001). Compared as potential reference standard diagnosis ARMD, sensitivity ion analysis or cut-off > 7...
Summary— Whilst prostatectomy remains the “gold standard” for treatment of outflow tract obstruction due to benign prostatic hyperplasia, medical treatment–if only symptomatic relief–appears be an attractive alternative. Most pharmacological agents in use block hormonal or sympathetic neurological pathways that influence prostate growth and function. All these drugs are known have side effects. Sixty patients with hyperplasia (BPH) were entered into a double‐blind, placebo‐controlled study...
<ns7:p>Background Curcumin, known for its anti-inflammatory properties, was selected the developing consumer friendly film forming spray that offers precise delivery of curcumin and improves patient adherence. Methods An optimized film-forming solution prepared by dissolving (1%), Eudragit RLPO (5%), propylene glycol camphor (0.5%) in ethanol: acetone (20:80) as solvent. The filled a container which contained 70% solutions 30% petroleum gas. <ns7:italic>In-vitro</ns7:italic> characterization...
Introduction: Anaemia is a condition in which the Haemoglobin (Hb) level blood below reference range for age and gender. In India, mild anaemia commonly found among medical students. Exercise capacity limited by ability to deliver oxygen muscles, can impair this process weakening respiratory thus reducing pulmonary function. Pulmonary Function Tests (PFTs), combined with bicycle exercise testing, are useful detecting occult cardiorespiratory limitations. Aim: To estimate prevalence of...
Ewing sarcoma is a malignant tumour found mainly in childhood and adolescence. The present study aims at analyzing the data on cases of bone from National Cancer Registry Programme, India to provide incidence, patterns, trends Indian population.The five Population Based Registries (PBCR) Bangalore, Mumbai, Chennai, Bhopal Delhi over 30 years period (1982- 2011) were used calculate Age Specific Standardized Incidence Rates (ASpR ASIR), incidence was analyzed by linear Joinpoint...
Abstract The Indian system of medicine, Ayurveda employs Bacopa monnieri extract (BME) for memory enhancement. This study attempts to prepare and test a more potent formulation by incorporating BME in nanovesicles. BME-loaded liposomes bilosomes (bile salt-stabilized liposomes) were formulated using soy phosphatidylcholine. Liposomes had homogeneous size distribution an average 285.7 nm 84 nm, respectively, with satisfactory zeta potential. Spherical multilamellar unilamellar observed under...
OBJECTIVESEndoscopic vein harvesting is one of the most popular minimally invasive vein-harvesting techniques for coronary artery bypass graft surgery. It associated with improved cosmetic outcome and fewer wound-related problems compared conventional open technique. However, its efficacy regard to conduit damage long-term patency has recently been questioned. Learning curve-associated trauma a major impact on quality incidence failure post-surgery. In an attempt address this problem, we...
Between December 2004 and June 2006, 136 patients (156 total hip replacements), were sent from the waiting list of Cardiff Vale NHS Trust to Treatment Centre, Weston-super-Mare, in an attempt reduce time for replacement. Because concerns about their outcome, each patient was contacted invited attend a review appointment with consultant specialising revision A 98 (113 hips) reviewed after mean 23 months (11 30). There 104 cemented hips, seven hybrid two cementless. An acetabular inclination >...
Objective: This study aimed to enhance the oral bioavailability of Ipriflavone (IP) and evaluate its osteogenic effect on human osteosarcoma cells (MG-63) by developing Ipriflavone-loaded Solid Lipid Nanoparticles (IP-SLN). Methods: IP-SLNs were prepared using a modified solvent evaporation method with probe sonication. Formulation optimization employed Central Composite Design (CCD) independent variables, including lipid amount, surfactant concentration, sonication time. Characterization...
To assess short- to medium-term outcome of the Omnifit constrained acetabular component in preventing dislocation at-risk patients after total hip arthroplasty (THA).81 (mean age, 77 years) underwent either primary or revision THA with an and were followed up clinically radiologically for a mean period 24 months.There was one avulsion acetabulum. The remaining prostheses remained well fixed.In medium-term, is effective recurrent patients. Long-term follow-up needed whether good fixation...
We report a radiological analysis of 281 primary cementless ABG total hip arthroplasties performed between 1991 and 1994, with mean follow-up 78 months. compare the polyethylene wear in hips Zirconia ceramic heads manufactured prior to introduction hot isostatic pressing cobalt chrome heads. The linear rate was 0.19 mm/yr 28mm (n=203), 0.20 32mm (n=47) 0.14mm/yr (n=31). matched each 31 patients patient from group for gender age. rates these two groups were 0.19mm/yr respectively (p<0.05)....
We report a radiological analysis of 281 primary cementless ABG total hip arthroplasties performed between 1991 and 1994, with mean follow-up 78 months. compare the polyethylene wear in hips Zirconia ceramic heads manufactured prior to introduction hot isostatic pressing cobalt chrome heads. The linear rate was 0.19 mm/yr 28mm (n=203), 0.20 32mm (n=47) 0.14mm/yr (n=31). matched each 31 patients patient from group for gender age. rates these two groups were 0.19mm/yr respectively (p<0.05)....
Anish John, Harsha Ashtekar, Dheeraj Gupta, Pankaj Kumar and Anoop V Narayanan* Author informationArticle notesCopyright License informationPDFCitations NITTE (Deemed to be University), NGSM Institute of Pharmaceutical Sciences, Mangalore, Karnataka, INDIA Corresponding author. Correspondence:Dr. Narayanan V, Assistant Professor, Department Pharmaceutics, Mangalore-575018, INDIA.
<title>Abstract</title> Conventional pharmacological therapies for erectile dysfunction (ED) primarily rely on PDE5 inhibitors such as Sildenafil, Tadalafil, Vardenafil, and Avanafil. While effective, these medications are reported to have side effects, especially among young men. Traditionally, plant-derived formulations with natural aphrodisiac potential been used treat ED, but they lack scientific validation. This study evaluates the efficacy of bioactive compounds from <italic>Tribulus...
The intricate interplay between gut microbiota and metabolic disorders has sparked interest in exploring probiotics as potential therapeutic agents for Polycystic Ovary Diseases (PCOD). It is a hormonal or endocrine disorder which combination of biochemical clinical including an imbalance reproductive hormones especially elevated androgen levels (male hormones) called hyperandrogenism. PCOD, also known PCOS (Polycystic Syndrome). disruption can affect the menstrual cycle, ovulation, other...