A5058868383- Sperm and Testicular Function
- Hormonal and reproductive studies
- Reproductive Biology and Fertility
- Prostate Cancer Treatment and Research
- Sexual Differentiation and Disorders
- AI in cancer detection
- Cancer, Stress, Anesthesia, and Immune Response
- Sexual function and dysfunction studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced Image and Video Retrieval Techniques
- Generative Adversarial Networks and Image Synthesis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- COVID-19 Impact on Reproduction
- Testicular diseases and treatments
- Nitric Oxide and Endothelin Effects
- Advanced Vision and Imaging
- Regulation of Appetite and Obesity
- Birth, Development, and Health
- Prostate Cancer Diagnosis and Treatment
- Hypothalamic control of reproductive hormones
- Dietary Effects on Health
- Thyroid Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Medical Image Segmentation Techniques
- 3D Shape Modeling and Analysis
University of Miami
2017-2025
Sylvester Comprehensive Cancer Center
2020-2025
University of Debrecen
2024
Brigham and Women's Hospital
2024
Washington State University Spokane
2023
Georgia Highlands College
2023
Florida International University
2022-2023
Baylor College of Medicine
2023
Amazon (Germany)
2021-2023
Amazon (United States)
2023
PURPOSE: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created a surge of research to help better understand the breadth possible sequelae. However, little is known regarding impact on semen parameters and fertility potential. We sought investigate for presence viral RNA in men with SARS-CoV-2 infection evaluate its effect ejaculate. MATERIALS AND METHODS: prospectively recruited thirty diagnosed using real-time reverse transcriptase polymerase chain reaction...
Our paper examines the key determinants of COVID-19 vaccination coverage in India and presents an analytical framework to probe whether vaccine hesitancy, socioeconomic factors multi-dimensional deprivations (MPI) play a role determining uptake. exploratory analysis reveals that hesitancy has negative statistically significant impact on coverage. A percentage increase can lead decline by 30 percent. Similarly, proportion people living poverty reduces unit MPI or acute leads mean 50 It...
Epithelial-mesenchymal transition (EMT) is an important parameter related to breast cancer survival. Among several microRNAs predicted target EMT-related genes, miR-506 a novel miRNA found be significantly patient survival in meta-analysis. suppressed the expression of mesenchymal genes such as Vimentin, Snai2, and CD151 MDA-MB-231 human cell line. Moreover, NF-κB bound upstream promoter region suppress transcription. Overexpression inhibited TGFβ-induced EMT adhesion, invasion, migration...
The activation of nuclear factor-kappa B1 (NFkB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency IR lung cancer, we screened for microRNAs (miRNAs) that suppress NFkB1 and observed their effects on radiosensitivity a human cell line. From time series data miRNA expression γ-irradiated H1299 cells, found miR-9 was inversely correlated with NFκB1. Overexpression down-regulated level NFκB1 surviving fraction decreased. Interestingly,...
Mathematical models for the behavior of fractional-N phase-locked-loop frequency synthesizers (Frac-N) are presented. The intended calculating rms phase error and determining spurs in output Frac-N. describe noise contributions due to charge pump (CP), detector (PFD), loop filter, voltage control oscillator, delta-sigma modulator. Models presented effects static CP gain mismatch, dynamic mismatch PFD reset delay mismatch. A simple analytic expression shows level /spl Delta//spl Sigma/...
The recent integration of open-source data with machine learning models, especially in the medical field, has opened new doors to studying disease progression and/or regression. However, ability use for approaches is limited by specificity a particular condition. In this context, most technologies, like generative adversarial networks (GANs), are being looked upon as potential way generate high-quality synthetic that preserve clinical variability despite some success, GAN model usage remains...
Significance This study presents insights into the underexplored areas of castration-resistant prostate cancer (CRPC) therapeutics—the role nitric oxide (NO) in CRPC reduction through its microenvironment. Results this provide important information on tumor capabilities increased NO levels and mechanistic aspect demonstrates potential long-term efficacy CRPC. An in-depth understanding how affects microenvironment will allow development chemotherapeutics based for a cure.
Metaverse is becoming the new standard for social networks and 3D virtual worlds when Facebook officially rebranded to in October 2021. Many relevant technologies are used metaverse offer immersive customized experiences at user's fingertips. Despite fact that receives a lot of attention advantages, one most pressing concerns its users safety their digital material data. As result decentralization, immutability, transparency, blockchain possible alternative. Our goal conduct comprehensive...
Abstract Exogenous testosterone therapy can be used to treat deficiency; however, it has several adverse effects including infertility due negative feedback on the hypothalamic–pituitary–gonadal (HPG) axis. Leydig stem cell (LSC) transplantation could provide a new strategy for treating deficiency, but clinical translatability of injecting cells inside testis is not feasible. Here, we explore feasibility subcutaneously autografting LSCs in combination with Sertoli and myoid increase...
Blockchain is basically a conveyed database that contains records and public record for all exchanges or computerized occasions have been performed shared among members. Every transaction in the checked by agreement of most individuals system. When data placed, won't ever vanish. Block chain conclusive undeniable each every ever. The primary rationale this proposed work safely store keeps up with patient cloud database. Healthcare serious space where lot created, dispersed, put away, got to...
Prostate cancer (PCa) is a leading cause of cancer-related mortality in men, with Gleason grading critical for prognosis and treatment decisions. Machine learning (ML) models offer potential automated but are limited by dataset biases, staining variability, data scarcity, reducing their generalizability. This study employs generative adversarial networks (GANs) to generate high-quality synthetic histopathological images address these challenges. A conditional GAN (dcGAN) was developed...
MicroRNA regulates cellular responses to ionizing radiation (IR) through translational control of target genes. We analyzed time-series changes in microRNA expression following γ-irradiation H1299 lung cancer cells using microarray analysis. Significantly changed IR-responsive microRNAs were selected based on analysis variance analysis, and predicted mRNAs enriched mitogen-activated protein kinase (MAPK) signaling. Concurrent mRNA profiles uncovered that miR-26b was down regulated, its...
In the realm of computational pathology, scarcity and restricted diversity genitourinary (GU) tissue datasets pose significant challenges for training robust diagnostic models. This study explores potential Generative Adversarial Networks (GANs) to mitigate these limitations by generating high-quality synthetic images rare or underrepresented GU tissues. We hypothesized that augmenting data pathology models with GAN-generated images, validated through pathologist evaluation quantitative...