A5005021801- Drug-Induced Hepatotoxicity and Protection
- Liver Disease Diagnosis and Treatment
- Tryptophan and brain disorders
- Dermatology and Skin Diseases
- Liver physiology and pathology
- Stress Responses and Cortisol
- TGF-β signaling in diseases
- Liver Diseases and Immunity
- Eosinophilic Esophagitis
- Polysaccharides and Plant Cell Walls
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Biochemical Analysis and Sensing Techniques
- Drug Transport and Resistance Mechanisms
- Medicinal Plant Pharmacodynamics Research
- Pharmacological Effects of Natural Compounds
- Helicobacter pylori-related gastroenterology studies
- Pediatric health and respiratory diseases
- Circadian rhythm and melatonin
- Urticaria and Related Conditions
- Hepatitis B Virus Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Chromatography in Natural Products
Hubei University of Chinese Medicine
2018-2023
ZheJiang Institute For Food and Drug Control
2011
Atopic dermatitis (AD), characterized by eczema as a chronic pruritic inflammatory skin disease, has become serious health problem with recurrent clinical episodes. However, current treatments have limited relief and are accompanied adverse effects. Therefore, there is necessity to develop new effective drugs for AD treatment. Angelica Yinzi (AYZ) classic ancient prescription nourishing blood, moistening dryness, dispelling wind, relieving itching. its mechanism alleviating atopic remains...
Abstract Asthma is characterized by airway inflammatory infiltration, which leads to remodeling and hyperreactivity. Coleus forskohlii (CFK) has been used treat asthma, however, the mechanism involved not clear. To explore antiasthma of extracts (ECFK), guinea pigs were administered with a spray phosphoric acid histamine, rats sensitized ovalbumin (OVA). Hematoxylin eosin staining (H&E) evaluate pathological changes in lung tissue. Enzyme‐linked immunosorbent assay (ELISA) was determine...
In Uygur medicine, Huganbuzure granule (HBG) is one of the classical prescriptions for liver protection. However, its role in immune injury remains unknown. This study evaluates effect HBG on concanavalin-A- (ConA-) induced and investigates protective underlying mechanism. BALB/c mice were randomly divided into five groups (n = 24 per group): control, ConA, 1.6 g/kg + 3.2 6 mg/kg prednisolone ConA. was intragastrically administrated once daily ten consecutive days, prior to ConA (20 mg/kg)...
Angelica Yinzi (AYZ) is a Chinese traditional herbal formula reported to attenuate itches and inflammation caused by atopic dermatitis (AD). However, the underlying mechanism of AYZ in attenuation itchiness remains unknown.
Background and objectivesDepression is a severe recurrent mental disease contributes to the global burden. However, there are limited effective treatments for depression. This study evaluated effect of compound Gaoziban tablet (CGZBT) on depression explored its potential mechanisms that underlie action in rats.
Liver and gut communicates with each other through metabolites the gut-liver axis plays a crucial role in lipid metabolism. Enterohepatic bile acid circulation is an important constitution of axis. Farnesoid X receptor (FXR)，a mediated nuclear receptor, promising therapeutic targets for non-alcoholic fatty liver disease (NAFLD). More more studies have confirmed effects Angelica sinensis polysaccharide (ASP) on protection regulation. However, little attention has been paid to ASP axis, which...