A5031807429- Retinal Diseases and Treatments
- Thyroid Disorders and Treatments
- Palliative Care and End-of-Life Issues
- Thyroid Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Cytokine Signaling Pathways and Interactions
- Advanced Glycation End Products research
- Geriatric Care and Nursing Homes
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Rheumatoid Arthritis Research and Therapies
- Pituitary Gland Disorders and Treatments
- Oral and Maxillofacial Pathology
- Glaucoma and retinal disorders
- Nutrition and Health in Aging
- Dysphagia Assessment and Management
- Dialysis and Renal Disease Management
- Cell Adhesion Molecules Research
- Stroke Rehabilitation and Recovery
- Oral health in cancer treatment
- Ophthalmology and Eye Disorders
- Nursing Roles and Practices
- Adipose Tissue and Metabolism
- Childhood Cancer Survivors' Quality of Life
Keio University Shonan Fujisawa
2024-2025
St. Luke's International University
2020-2024
Keio University
2022-2024
Yamagata University
2024
Oita University
2023
Nagoya Bunri University
2022
Osaka City University
2022
Aichi Medical University
2022
Japanese Foundation For Cancer Research
2015-2021
Nippon Sport Science University
2021
Purpose : To examine the factors that influence work satisfaction of a national sample registered nurses in metropolitan statistical areas (MSAs). Design A cross‐sectional mailed survey design was used. The consisted RNs randomly selected from 40 MSAs 29 states; 1,907 responded (48%). 1,538 working nursing used for analysis. Methods questionnaire included measures attitudes and demographic characteristics. data were analyzed using ordinary least‐squares regression. Findings More than 40%...
機能的嚥下障害スクリーニング法として,「反復唾液嚥下テスト」(the Repetitive Saliva Swallowing Test: RSST)を考案した.30秒間の平均空嚥下回数は若年者(N=30)で7.4回,高齢者(N=30)で5.9回,30秒間の平均人工唾液嚥下回数は若年者で7.7回,高齢者で6.2回であった.空嚥下,人工唾液嚥下ともに高齢者は若年者より有意に嚥下回数が少なかった.一方,若年者,高齢者それぞれの空嚥下と人工唾液嚥下の嚥下回数には有意差を認めなかった.嚥下運動の確認は喉頭挙上の触診で可能であった.高齢者の積算嚥下時間(検査開始から嚥下完了時点までの時間)上限より,RSST 2回/30秒間以下が嚥下障害のスクリーニング値として設定できた.
Background: The management of Graves' disease (GD) in children is associated with a dilemma. Although the established initial treatment for GD antithyroid drug (ATD) treatment, remission rate said to be lower than adults, and severe propylthiouracil-induced adverse events (AEs) are an issue. Definitive treatments effective, but they often result permanent hypothyroidism need lifelong T4 supplementation. Objective: objective this study was investigate outcome ATD identify significant...
Although the lipophilic yeasts of genus Malassezia are part cutaneous microbiota in healthy individuals, they also associated with several skin diseases, such as seborrheic dermatitis. However, effects age and gender on have not been completely elucidated. We analyzed 770 Japanese using highly accurate real-time PCR a TaqMan probe to investigate population. The numbers cells increased males up 16-18 years females 10-12 old, subsequently decreased gradually both genders until senescence....
Aims and objectives To explore the association between workplace bullying environment factors among nurses in Japan. Background Workplace is increasing globally occurs more frequently than other professions. However, there little information on impact of nurse Design A cross‐sectional survey using a self‐administered questionnaire. Methods Participants were 1152 recruited at seminars or training courses outside their workplaces Tokyo. was measured Negative Acts Questionnaire‐Revised....
Background: Methimazole (MMI) is usually used at an initial dose of 30 mg/day for severe Graves' disease (GD) hyperthyroidism, but adverse effects are more frequent this than MMI 15 mg/day. Objectives: We designed a regimen to address the lack primary therapeutic effect by combining it with inorganic iodine 38.2 Our aim was compare two regimens (MMI mg+inorganic (M15+I) vs. (M30)) in terms effect, effects, and remission rate. Design Patients: In prospective study, 310 patients untreated GD...
Background This report investigates the applicability of nursing support for patients with cancer a prognosis months and weeks, their families. Objectives To evaluate five symptoms (dyspnea, pain, nausea/vomiting, constipation, delirium) in during last weeks life, caregiver burden on Design Setting A Delphi study was used to determine terminal Eight experts symptom palliation Japan who have direct care or research experience these populations were included. The method assess types prognoses...
Thyroid ultrasonography (US) is the most sensitive method for detecting thyroid nodules, and US-guided aspiration biopsy accurate diagnostic procedure nodules. We performed this retrospective study to establish prevalence of nodules in Graves' disease patients with Hashimoto's thyroiditis at time their initial visit.We US as routine screening 1652 2036 fine-needle when diameter a nodule >1 cm or was suspected being malignant.The papillary carcinoma higher than (1.77% vs. 0.97%), two (0.098%)...
Obesity and insulin resistance, the key features of metabolic syndrome, are closely associated with a state chronic, low-grade inflammation characterized by abnormal macrophage infiltration into adipose tissues. Although it has been reported that chemokines promote leukocyte migration activating class IB phosphoinositide-3 kinase (PI3Kγ) in inflammatory states, little is known about role PI3Kγ obesity-induced tissues, systemic inflammation, development resistance. In present study, we used...
Bone fractures markedly reduce quality of life and expectancy in elderly people. Although osteoporosis increases bone fragility, frequently occur patients with normal mineral density. Because most on falling, preventing falls is another focus for reducing fractures. In this study, we investigated the role vitamin D receptor (VDR) signaling locomotive ability. rotarod test, physical exercise enhanced ability wild-type (WT) mice by 1.6-fold, whereas did not enhance VDR knockout (KO) mice....
The aim of the present study was to establish new reference intervals for serum thyrotropin (TSH) levels in Japanese subjects without antithyroid antibodies. We reviewed TSH level all patients 20 years age and over who attended outpatient clinic our hospital between January 1, 2003, September 20, 2010. thyroid gland every patient examined by ultrasonography, found have a normal were chosen. following excluded: with past history diseases; whose positive antibodies; pregnant women; taking...
Abstract Objective: The present study sought to examine the impact of physical symptoms, facial disfigurement, adequacy preoperative information, and social support on anxiety depression in Japanese patients with head neck cancer (HNC) who had undergone surgery. Method: A cross-sectional 194 was conducted using a self-administered questionnaire. This instruments included Hospital Anxiety Depression Scale (HADS), European Organization for Research Treatment Cancer (EORTC) Head Neck module...
Thyroid-associated orbitopathy (TAO) is characterized by immune-mediated inflammation of the extraocular muscles surrounding orbital connective tissue and adipose tissue. Severe related to autoimmune thyroid disease often occurs in patients with Grave's disease, but it rare Hashimoto's thyroiditis. The pathogenesis TAO unclear. Several studies have noted a strong correlation between levels antibodies thyrotropin receptor antibody (TRAb) Graves' disease. Mild upper eyelid retraction has been...
Exacerbation of Graves' orbitopathy (GO) after radioiodine (RAI) therapy has been examined in some populations but not fully described Japanese populations.The purpose this study was to clarify the characteristics GO exacerbation RAI and effectiveness low-dose prophylactic corticosteroid (PCS).This a prospective randomized Tokyo, Japan.Between June 2011 2012, 295 patients with disease either inactive or no received therapy. Of these, 147 PCS (PCS-Off group), whereas 148 (starting dose, 15...
The purpose of this study was to investigate the expression level adiponectin and its related molecules in hypertrophied atrophied skeletal muscle mice. also evaluated C2C12 myoblasts myotubes. Both mRNA protein adiponectin, receptor (AdipoR) 1 AdipoR2, adaptor containing pleckstrin homology domain, phosphotyrosine binding leucine zipper motif (APPL1) were observed myoblasts. levels these myotubes higher than those adiponectin-related soleus at (adiponectin, AdipoR1, AdipoR2) APPL1) levels....
Reference ranges for serum thyroid hormones free triiodothyronine (FT3), thyroxine (FT4) and stimulating hormone (TSH) in children were set using the assay kits currently used clinical settings. A total of 342 (111 males 231 females) who negative antithyroid antibodies (TgAb, TPOAb) found to have no abnormalities on ultrasonographic examination gland divided into 6 age groups: 4-6 years (45 children), 7-8 (40), 9-10 (53), 11-12 (65), 13-14 (83), 15 (56) study. FT3, FT4 TSH levels determined...