A5047283246- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Antifungal resistance and susceptibility
- SARS-CoV-2 and COVID-19 Research
- Fungal Infections and Studies
- COVID-19 and Mental Health
- Antibiotic Use and Resistance
- Vaccine Coverage and Hesitancy
- COVID-19 and healthcare impacts
- Cardiovascular Health and Disease Prevention
- Infection Control and Ventilation
- Inflammasome and immune disorders
- Cardiovascular Disease and Adiposity
- Intensive Care Unit Cognitive Disorders
- Antimicrobial Resistance in Staphylococcus
- Pharmaceutical Practices and Patient Outcomes
- Female Genital Mutilation/Cutting Issues
- Infective Endocarditis Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Pesticide Exposure and Toxicity
- Vitamin C and Antioxidants Research
- Respiratory Support and Mechanisms
- Methemoglobinemia and Tumor Lysis Syndrome
- Infectious Aortic and Vascular Conditions
Amrita Institute of Medical Sciences and Research Centre
2018-2025
Amrita Vishwa Vidyapeetham
2022
Pondicherry Institute of Medical Sciences
2014
India introduced BBV152/Covaxin and AZD1222/Covishield vaccines in January 2021. We estimated the effectiveness of these against severe COVID-19 among individuals aged ≥45 years.We did a multi-centric, hospital-based, case-control study between May July Cases were patients, controls negative from 11 hospitals. Vaccine (VE) was for complete (2 doses ≥ 14 days) partial (1 dose 21 vaccination; interval two vaccine vaccination Delta variant. used random effects logistic regression model to...
Self-medication involves the use of medicinal products by a consumer to treat self-recognized disorders or symptoms intermittent continued medication prescribed physician for chronic recurring diseases symptoms. Practicing self-medication antibiotics is major factor fueling emergence drug resistance. This study would help health-care providers in creating public awareness on dangers antibiotic abuse.The aim was assess prevalence and pattern an urban population Kerala.A community-based...
Abstract Background With the World Health Organization (WHO) declaring an end to COVID-19 pandemic, focus has shifted understanding and managing long-term post-infectious complications. “Long COVID,“ characterized by persistent or new onset symptoms extending beyond initial phase of infection, is one such complication. This study aims describe incidence, clinical features risk profile long COVID among individuals in a South Indian cohort who experienced post-ChAdOx1 n-Cov-2 vaccine...
Post-acute sequelae of SARS-CoV-2 infection (PASC) represent a significant challenge in patient care, with symptoms persisting beyond three month's post-recovery. This study aimed to evaluate the incidence PASC at one year post-COVID-19 and identify predictive biomarkers comorbidities for effective risk stratification. A cohort 120 adult patients, including 50 intensive care 70 non-intensive was followed up two weeks, six one-year post-discharge using structured questionnaires. The...
Background Metabolic syndrome (syndrome X) is the name for a group of risk factors that raises your heart disease and other health problems, such as diabetes stroke. Dilatation blood vessels following stress function vasodilators produced by endothelium. Flow-mediated vasodilation assesses endothelial function. In case dysfunction, flow-mediated impaired, resulting in decreased or even absence stress. The easy availability ultrasound machines nowadays non-invasive nature test make this...
Abstract Background Coronavirus disease 2019 (COVID-19)–associated pulmonary aspergillosis (CAPA) is a life-threatening fungal infection. Studies focusing on CAPA in low- and middle-income countries are limited. Methods This retrospective matched case-control study was conducted at tertiary care center South India. Cases of were classified using the 2020 European Confederation Medical Mycology/International Society for Human Animal Mycology consensus criteria. A total 95 cases 1:1 with...
Background: India introduced BBV152/Covaxin and AZD1222/Covishield vaccines from January 2021. We estimated effectiveness of these against severe Coronavirus disease 2019 (COVID-19) among individuals aged >=45 years.Methods: did a multi-centric, hospital-based, case–control study between May July Cases were COVID-19 patients controls negative 11 hospitals. Vaccine (VE) was for full (2 doses ≥14days) partial (1 dose ≥21 days) vaccination; duration two vaccine the Delta variant. used random...
Organophosphorus poisoning is common in rural Asia. Clinical features result from overactivity of acetylcholine receptors. Blackish discoloration urine not a feature organophosphorus poisoning. Only one case black colored following quinalphos has been reported literature. We report two cases different compounds, which patients passed urine, the absence haemolysis or rhabdomyolysis. These indicate that blackish might be as uncommon it was believed to be. Besides, urinary excretion metabolites...
A 68-year-old female, with a known case of mantle cell lymphoma, came complaints persistent cough expectoration for three months, not responding to multiple courses antibiotics. Bronchoscopy was done and bronchoalveolar lavage (BAL) culture revealed Penicillium species. She started on IV liposomal amphotericin B 14 days then switched oral itraconazole which showed response treatment. Early diagnosis penicilliosis prompt treatment are important as it is rare associated high mortality rate.
A male in his 40's with no known comorbidities developed severe COVID-19 pneumonia and received a four-week course of methylprednisolone. The patient subsequently disseminated Aspergillus endocarditis, manifesting as multiple organ involvement including the heart, eyes, brain. Despite poor prognosis generally associated fungal survived following aggressive medical management combination liposomal amphotericin b voriconazole therapy is now doing well for over two years off antifungal year.
Hypertension is the most prevalent non communicable disease causing deaths even before evidence of target organ damage. Platelet activation associated with risk vascular events. Identification mean platelet volume (MPV) values in patients hypertensive retinopathy (HR) can help prognostication and stratification possible complications.
Abstract Objective: This study aimed to asses the impact of a physical barrier-based infection prevention and control (IPC) intervention in patient wards at tertiary care center on patient-to-patient coronavirus disease-2019 (COVID-19) transmission cluster formation. Materials Methods: A quasi-experimental was conducted 1300-bedded South Indian center. Barrier curtains were deployed between ward beds, accompanied by social interaction protocol, eight locations, each containing eleven...
BackgroundDespite broad COVID-19 vaccination coverage in India, hesitancy persists, limiting the achievement of 100 % across country to prevent ongoing transmission infection. We explored key drivers vaccine among unvaccinated adults semi-urban regions Kerala, India.Methodology: Semi-structured face-to-face interviews were conducted from April May 2022, using purposive sampling enroll participants with help Accredited Social Health Activist (ASHA) workers. Participation was voluntary and at...
Syphilis, a bacterial sexually transmitted infection, poses diagnostic challenges due to its diverse clinical manifestations. This report presents two distinctive cases illustrating the dilemmas and management strategies associated with syphilis. The first case describes male in his early 30s presenting secondary syphilis condyloma lata, atypical genital lesions that can arise. second involves late 40s latent exhibiting unusual cutaneous manifestations, underscoring complexities of disease....
Tuberculosis (TB) remains a significant public health challenge in Low- and Middle-Income Countries (LMIC). Inappropriate use of Anti-Tubercular Treatment (ATT) undermines treatment efficacy could contribute to drug resistance. While antimicrobial stewardship programs (AMSP) are well established, anti-tubercular (ATTSP) private hospitals do not have an established model. An AMSP model tertiary care hospital South India was repurposed monitor the prescription appropriateness ATT. A...
Abstract Background The high exposure risk to COVID among frontline heathcare workers was a major challenge healthcare systems across the globe that warranted close monitoring through assessment and contact tracing strategies. objective of our study characterize factors for transmission subsequent positivity frontlinehealthcare in institution during pandemic period. Methods retrospective observational conducted over period 6 months from June 2020 November at 1300-bedded South Indian tertiary...
Extrapyramidal symptoms comprise a group of movement disorders dystonia, akathesia, tardative dyskinesia and parkinsonism.Drug induced extrapyramidal are known for decades yet the use these drugs still prevail with adverse effect skipped or looked over.Presenting case an eighteen year old male hailing from low socioeconomic status brought complaints fever was diagnosed to have meningitis.He sedated one stat dose haloperidol MRI brain, following which he developed acute dystonic reaction that...
Abstract Background The majority of existing literature on long COVID has been focused hospitalised patients. However, in the real-world setting post-vaccination era where breakthrough infections are norm, it becomes a priority to assess clinical profile symptoms among such individuals. Through our study, we aim describe incidence, characterise and stratify risk developing infections. Methods This prospective observational study included adult patients with COVID-19 diagnosed at tertiary...
Abstract Background The objective of this study was to assess the exposure risk factors for transmission and subsequent infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) among frontline health-care workers (HCWs) in a South Indian tertiary care center during COVID-19 pandemic. Methods This retrospective, observational conducted over period 6 months, from June 2020 November 2020. Participants included HCWs who completed assessment identify encounters with...
Abstract Background The majority of existing literature on long COVID has been focused hospitalised patients. However, in the real-world setting post-vaccination era where breakthrough infections are norm, it becomes a priority to assess clinical profile symptoms among such individuals. Through our study, we aim describe incidence, characterise and stratify risk developing infections. Methods This prospective observational study included adult patients with COVID-19 diagnosed at tertiary...
Abstract Background Post-COVID-19 conditions represent a significant challenge in patient care, with symptoms persisting beyond three month’s post-recovery. This study aimed to evaluate the incidence of post-COVID-19 at one year and identify predictive biomarkers comorbidities for effective risk stratification. Methods A cohort 120 adult patients, including 50 intensive care 70 non-intensive was followed up two weeks, six one-year post-discharge using structured questionnaires. The...
Abstract Introduction and Aim: The COVID-19 pandemic struck the world in a way that had never been seen before, offering significant problems to health-care system. Vitamin D insufficiency was one of earliest risk factors be investigated for possible link development severe pneumonia. current study aimed explore association clinical outcomes patients with serum 25(OH)D levels at admission. Methodology: This prospective conducted on COVID-19-positive admitted tertiary care hospital South...
Introduction: The ability of modern technology to substitute for life threatening respiratory failure is the signature intensive care medicine where mechanical ventilation has played a primary role.The main aim Mechanical should be provide supportive support with least risk patient.The this study was clinical outcomes and its determinants in mechanically ventilated patients ICU.Methods : This prospective observational conducted medical ICU Pondicherry Institute Medical Sciences, Pondicherry,...
Abstract Background Baricitinib is a Janus kinase inhibitor with known anti-inflammatory effects and has been explored for beneficial outcomes in COVID-19 therapeutic management however paucity of data on its secondary infections thrombosis. We aimed to assess the efficacy all-cause mortality among moderate severe COVID − 19 retrospective cohort patients who received adjunct baricitinib as compared matched standard care Covid 19. Methods The case control study conducted at 1300-bedded South...