João Machado

ORCID: 0000-0003-3162-9170
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About
Contact & Profiles
Research Areas
  • Tracheal and airway disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Respiratory Support and Mechanisms
  • Cystic Fibrosis Research Advances
  • Tuberculosis Research and Epidemiology
  • Fungal Infections and Studies
  • Nail Diseases and Treatments
  • Obstructive Sleep Apnea Research
  • Neuroscience of respiration and sleep
  • Drug-Induced Hepatotoxicity and Protection
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Pediatric health and respiratory diseases
  • Foreign Body Medical Cases
  • Traumatic Ocular and Foreign Body Injuries
  • Vascular Anomalies and Treatments
  • Cultural, Media, and Literary Studies
  • Social and Economic Solidarity
  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Autopsy Techniques and Outcomes
  • Neonatal Respiratory Health Research
  • Liver Disease Diagnosis and Treatment
  • Asthma and respiratory diseases
  • Liver Disease and Transplantation
  • HIV Research and Treatment

Instituto Politécnico de Leiria
2023

Hospital de Santo António
2023

Hospitais da Universidade de Coimbra
2017-2022

Hospital Prof. Dr. Fernando Fonseca
2019-2021

University of Coimbra
2016-2019

Hospital Curry Cabral
2001-2018

NHS Blood and Transplant
2017

Centro Hospitalar de Lisboa Central
2015

Screening methods have become increasingly important due to the growing number of patients suspected having obstructive sleep apnea (OSA) being referred clinics. The Lausanne NoSAS (Neck circumference, Obesity, Snoring, Age, Sex) score test is a simple, efficient, and easily employed tool enabling identification individuals at risk for disease. ranges from 0 17 patient has high probability OSA if they 8 or higher.To evaluate performance as screening diagnosis in clinic.Prospectively, 12...

10.1016/j.pulmoe.2019.04.004 article EN cc-by-nc-nd Pulmonology 2019-06-10

Bronchiectasis (BC) is a multidimensional and etiologically diverse disease and, therefore, no single parameter can be used to determine its overall severity prognosis. In this regard, two different validated scores are currently assess the of non-cystic fibrosis bronchiectasis (NCFB): FACED score Severity Index (BSI).

10.1016/j.rppnen.2017.08.009 article EN cc-by-nc-nd Pulmonology 2018-01-03

Benign prostatic hyperplasia (BPH) is the most common canine disorder. Although or even all intact male dogs may develop BPH by 5-8 years of age, many show no clinical signs. Taking into account non-specific character and ultrasonographic findings, a new diagnostic approach has recently been proposed based on augmentation blood prostate-specific arginine esterase (CPSE) in hyperplasic dogs. The aim present study was to verify CPSE levels negative controls dogs, considering cytological...

10.1186/s12917-017-0996-5 article EN cc-by BMC Veterinary Research 2017-03-23

Between Reality and Imagination: Art in the Construction of Human explores how art emerges as an essential link between human experience creative capacity, connecting tangible to imaginary. Since primitive times, has reflected condition, enabling expression emotions, storytelling, construction cultural identities. Artistic creativity transcends social historical boundaries, functioning a mirror projecting complexities nuances existence. In this context, not only imitates life but interprets...

10.69849/revistaft/ni10202503091716 article EN Revista fisio&terapia. 2025-03-09

The spectacle of consumption represents one the main instruments domination in contemporary capitalism, transforming desires into commodities and assigning superficial values to human experience. capitalist logic organizes society around an incessant production consumption, exploiting subjectivities turning individuals compulsive consumers. Subjectivity is suffocated as value each individual measured by their ability consume display symbols status. This dynamic perpetuates inequalities,...

10.69849/revistaft/ni10202503091624 article EN Revista fisio&terapia. 2025-03-09

The transformations of modernity have caused profound changes in social dynamics, influencing behaviors, interactions, and collective structures. Advances technology, globalization, new forms communication impact interpersonal relationships the way societies organize themselves. digitization life, increased connectivity, speed information create challenges for identity, privacy, cohesion. Additionally, inequalities are intensified by a dynamic job market, automation, constant need...

10.69849/revistaft/ni10202503091649 article EN Revista fisio&terapia. 2025-03-09

Background: Case report, in a patient with history of diabetes and hypertension, treated metformin, gliclazide, enalapril + hydrochlorothiazide, amlodipine, aspirin diazepam, recently medicated for gouty crisis colchicine clonixin without improvement. Believing it could help the treatment symptoms he took about 1.5 L artichoke infusion (Cynara cardunculus). He felt better did agriculture work but developed distal muscle pain, severe anemia, standard biochemical liver cholestasis, increase...

10.2174/1574886312666170912163746 article EN Current Drug Safety 2018-03-27

The Modified British Medical Research Council Questionnaire is considered an adequate and simple measure of breathlessness in chronic obstructive pulmonary disease. It widely used clinical practice Portugal, but it still lacks confirmatory evaluation for the Portuguese setting. aim this study was to perform a cultural adaptation validation so that its most suitable version can be made available researchers clinicians Portugal.We performed cross-sectional descriptive involving patients with...

10.20344/amp.15208 article PT cc-by-nc-nd Acta Médica Portuguesa 2021-04-20

Acute-on-chronic liver failure (ACLF) is a syndrome characterized by an acute deterioration of patient with cirrhosis, frequently associated multi-organ and high short-term mortality rate. We present retrospective study that aims to characterize the presentation, evolution, outcome patients diagnosed ACLF at our center over last 3 years, comparative analysis between group had precipitated infectious insults bacterial origin those triggered nonbacterial insult; incidence kidney injury its...

10.1159/000478988 article EN cc-by-nc-nd GE Portuguese Journal of Gastroenterology 2017-08-23

Currently there has been significant growth in the number of patients with suspected obstructive sleep apnea (OSA) referred to clinics. In this sense, screening and stratification methods severity pathology have become increasingly relevant.To evaluate performance NoSAS STOP-Bang scores OSA a clinic.Prospectively, for 12 months, all by primary care physicians our unit clinical evaluation who underwent in-lab polysomnography (PSG), also completed score (Neck circumference, Obesity, Snoring,...

10.1590/1806-9282.66.9.1203 article EN Revista da Associação Médica Brasileira 2020-09-01

Introduction: Tuberculosis incidence in Portugal ranged from 20 to 22 cases per 100 000 inhabitants between 2010 and 2014. liver transplant recipients is not precisely known, but it estimated be higher than among the general population. particularly challenging because of atypical clinical presentation side effects antibacillary drugs their potential interactions with immunosuppressive therapies.Material Methods: We retrospectively reviewed records post-transplant tuberculosis occurring...

10.20344/amp.7052 article EN cc-by-nc-nd Acta Médica Portuguesa 2017-01-31

Sarcopenia is defined as a progressive loss of skeletal muscle mass and strength related to age comorbidities. Worldwide sarcopenia's prevalence varies between 10-40%, being associated with functional impairment, lower quality life, higher mortality. can be estimated based on age, calf circumference, handgrip (Ishii's formula). Early diagnosis essential because treatment nutritional support rehabilitation programs prevent complications. The aim the study was assess probable sarcopenia in...

10.7759/cureus.49158 article EN Cureus 2023-11-21

Correspondence to: Joao Figueira-Coelho, MD Rua Domingos Sequeira, Emp. Amorosa Place Ed. 2, Bloco B, 6o A 2675-338 Odivelas – Portugal Phone: +351-933260906 E-mail: jffcoelho@ gmail.com Dear Editor, The authors present a case of atypical severe (malignant) Mediterranean spotted fever, with brief review on the subject. Although not previously described in Brazil, possibility imported cases, especially from Portuguese tourists, is real. This report highlights form disease and presentation...

10.1016/s1413-8670(10)70044-1 article EN cc-by-nc-nd The Brazilian Journal of Infectious Diseases 2010-05-01

This is a report on rare case of acquired stenosis the descending thoracic aorta resulting from an extreme posttuberculotic gibbous formation. The unusual anatomical relationship precluded conventional alleviation which was bridged ultimately with graft producing satisfactory functional result.

10.1055/s-2007-1023345 article EN The Thoracic and Cardiovascular Surgeon 1984-02-01

Pure red cell aplasia (PRCA) is a rare bone marrow failure characterized by progressive normocytic anemia and reticulocytopenia without leukopenia thrombocytopenia. It can be associated with various hematological disorders but exceedingly rarely angioimmunoblastic T-cell lymphoma (AITL). We report the case of 72-year-old woman PRCA AITL. The patient presented severe (hemoglobin 2.6 g/dL) low reticulocyte count 0.7%. Direct indirect Coombs tests were positive. A CT scan chest, abdomen, pelvis...

10.1159/000505533 article EN cc-by-nc Case Reports in Oncology 2020-02-06

Background: Although endemic in West Africa, HIV-2 infection dissemination is limited to about 1.2 million people worldwide.However, the prevalence of Portugal disproportionately high, similarly other countries with strong socioeconomic ties African former colonies.Due intrinsic resistance non-nucleoside reverse transcriptase inhibitors (non-NRTIs) and enfuvirtide, along reduced susceptibility several protease (PI), antiretroviral therapy (ART) relies on a regimen containing two NRTIs...

10.9734/ijmpcr/2015/13078 article EN International Journal of Medical and Pharmaceutical Case Reports 2015-01-06
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