A5087935170- Animal Nutrition and Physiology
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Helminth infection and control
- Coccidia and coccidiosis research
- Mycotoxins in Agriculture and Food
- Clostridium difficile and Clostridium perfringens research
- Bone Metabolism and Diseases
- Parasitic Infections and Diagnostics
- Viral gastroenteritis research and epidemiology
- Microbial infections and disease research
- Connective tissue disorders research
- Aquaculture disease management and microbiota
- Effects of Environmental Stressors on Livestock
- Escherichia coli research studies
- Meat and Animal Product Quality
- Cancer, Hypoxia, and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Trace Elements in Health
- High Altitude and Hypoxia
- Rabbits: Nutrition, Reproduction, Health
- Cancer-related molecular mechanisms research
- Lipid metabolism and disorders
- Livestock and Poultry Management
Henan Agricultural University
2017-2025
Jiangsu University of Science and Technology
2023-2024
Hunan Agricultural University
2022-2024
Zhejiang Chinese Medical University
2024
Southwest Minzu University
2023
State Ethnic Affairs Commission
2023
Zhejiang Provincial Hospital of TCM
2019-2023
Huazhong Agricultural University
2016-2019
Tibet University
2019
Mackay Memorial Hospital
2010
Aflatoxin B1 (AFB1) is an unavoidable environmental pollutant commonly found in feed and foodstuffs. It the most toxic one of all aflatoxins, which can cause severe impairment to testicular development function. Yet, underlying mechanisms reproductive toxicity rams sheep remain inconclusive. The study was designed explore effects AFB1 on testes through rumen-microbiota, oxidative stress apoptosis. Six-month-old male Dorper (n = 6) were orally administrated with 1.0 mg/kg (dissolved 20 mL 4%...
Abstract Tibial dyschondroplasia (TD) with multiple incentives is a metabolic skeletal disease that occurs in fast-growing broilers. Perturbations the gut microbiota (GM) have been shown to affect bone homoeostasis, but mechanisms by which GM modulates metabolism TD broilers remain unknown. Here, using broiler model of TD, we noted elevated blood glucose (GLU) levels broilers, accompanied alterations pancreatic structure and secretory function damaged intestinal barrier function....
Aflatoxin B1 (AFB1) is a common mycotoxin that widely occurs in feed and has severe hepatotoxic effects both humans animals. Total flavonoids of Rhizoma Drynaria (TFRD), traditional Chinese medicinal herb, have multiple biological activities potential hepatoprotective activity. This study investigated the protective mechanisms TFRD against AFB1-induced liver injury. The results revealed supplementation with markedly lessened broiler intestinal permeability by increasing expression tight...
Abstract Polysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities essential growth development living organisms. As natural products with inherent activity, polysaccharides widely available, nontoxic, possess numerous functional properties, holding immense potential advancement in food, medicine, cosmetics....
Aflatoxin B1 (AFB1) is an unavoidable contaminant in animal feed and agricultural products. AFB1 has been found to impair the liver kidney function of sheep. However, few data are available, which explain toxic damage exposure on meat quality. In study, male Dorper RAMS sheep (6-month-old) were orally administrated with at dose 1 mg/kg body weight once. The temperature, serum biochemistry, quality-related parameters, oxidation indicators serum, mRNA expression pro-inflammatory cytokines...
Fungicide thiram, a representative dithiocarbamate pesticide can cause potential health hazards to humans and animal due the residues in various agricultural products. However, effects of thiram on lipid metabolism by perturbing gut microbiota chickens are not clear. Our study was aimed explore protective polysaccharide extracted from Morinda officinalis (MOP) acute thiram-exposed chickens, analyze association between alteration metabolism. Three hundred chicks fed with normal diet,...
Aflatoxin B1 (AFB1) is a common mycotoxin in food and the environment that lead to multi-organ injury humans animals. The objective of this study was evaluate detoxification properties dietary total flavonoids Rhizoma drynariae (TFRD), Chinese herbal, on aflatoxin (AFB1)-induced hepatic oxidative damage apoptosis liver broiler chickens. A 160 healthy specific pathogen free (SPF) 21-day-old broilers were randomly allocated 4 groups, including CON group (basal diet), TFRD diet with 125 mg/kg...
Meat from sheep offers an abundance of essential amino acids and trace elements for optimal human health a delectable culinary delight. Because it has fewer calories lower cholesterol content than other meats, this succulent meat is not only delicious but also nutritious choice. Globally, discriminating consumers have expressed profound appreciation its irresistible flavor composition. High-quality breeds lamb quality are in the spotlight as market grows. Nevertheless, demand rapid growth...
Tibial dyschondroplasia (TD) is an intractable poultry problem that characterized by the appearance of non-vascularized and non-mineralized cartilage masses in tibial growth plates (TGPs). However, role angiogenesis inhibition occurrence TD remains unknown. In this study, we found that, compared to low-altitude Arbor Acres chickens (AACs), high-altitude Tibetan showed higher vascular distributions were accompanied up-regulation hypoxia-inducible factor-1α (HIF-1α), endothelial factor A...
Abstract Tibial dyschondroplasia (TD) is the most-prevalent leg disorder in fast-growing chickens; it intractable and characterized by abnormal endochondral bone formation of proximal tibial growth-plates (TGPs). Previous studies have shown that a highly vascularized tissue dependent on coordinated coupling between angiogenesis osteogenesis, but underlying mechanisms remodeling are poorly defined TD chickens. Here, we observed inhibition vasculogenesis remarkably impaired vascular invasion...
The effects of dietary supplementation essential oil on growth performance, carcass yield, meat quality, serum antioxidant capacity, and intestinal tight junctions broilers with or without Eimeria challenge were investigated. A total 576 one-day-old male randomly separated into 8 treatments (6 replication floor-pens per treatment, 12 pen) in a 4 × 2 factorial design. diets consisted 1) corn soybean meal basal diet, 2) an anticoccidial diet (60 g nicarbazin 60 narasin ton feed), 3) oregano...
Ruminants serve as one of the most important reservoirs for pathogenic Escherichia coli. Infection with E. coli, a foodborne enteropathogen, can lead to asymptomatic infections that cause life-threatening complications in humans. Therefore, from clinical and human health perspective, it is know which virulence genes, phylogenetic groups, serogroups, antibiotic resistance patterns are present coli strains yaks diarrheic infections.Two-hundred ninety-two rectal swabs were collected Qinghai...
Tibal dyschondroplasia (TD) is main bone problem in fast growing poultry birds that effect proximal growth plate of tibia bone. TD broadly defined as non-vascularized and non-mineralized, enlarged GP with deformation lameness. Icariin (Epimedium sagittatum) a traditional Chinese medicine, which commonly practiced the treatment various diseases. Recently, many researcher reports about beneficial effects relation to types conditions but no report available promoting icariin against TD....
In the present study, we analyzed effects of Glycyrrhiza polysaccharide (GCP) on growth performance, serum antioxidant capacity, and biochemistry broilers. A total 600, one-day-old AA broilers randomly divided into 5 treatment groups with 6 replicate pens 20 birds per cage received dietary supplementation GCP (0, 200, 500, 1,000, 1,500 mg/kg) for 42 d. The linearly decreased (P < 0.05) feed conversion rate day 22 to 42. Dietary reduced cholesterol 21 improved albumin high-density lipoprotein...
Icariin (ICA) is a naturally occurring phytochemical agent primarily extracted from Epimedium Brevicornum Maxim (Family Berberidaceae) with broad spectrum of bioactivities. Endometritis uterine disease that causes enormous losses in the dairy industry worldwide. In this study, anti-inflammatory and anti-oxidant properties ICA were investigated against lipopolysaccharide (LPS)-induced endometritis mice to investigate possible underlying molecular mechanisms. Sixty heathy female Kunming...
Tibial dyschondroplasia (TD) is one of the most common problems in poultry industry and leads to lameness by affecting proximal growth plate tibia. However, due unique environmental geographical conditions Tibet, no case TD has been reported Tibetan chickens (TBCs). The present study was designed investigate effect high altitude hypoxia on blood parameters tibial development using complete count, morphology, histological examination. results this showed an undesirable impact overall...
Tibial dyschondroplasia (TD) is one of the common skeletal abnormalities in fast-growing birds, and it characterized by nonvascularized, unmineralized, nonviable cartilage tibial growth plate that fails to form bone. The aim this study was check vitro effect apigenin danshen on heat-shock protein 90 (Hsp90) vascular endothelial factor (VEGF) expressions avian cells treated with sublethal concentration thiram. Initially, chondrocytes from chicken plates were isolated culturx ed medium without...