A5040564822- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- COVID-19 and Mental Health
- Nutritional Studies and Diet
- Healthcare professionals’ stress and burnout
- Renal function and acid-base balance
- Arsenic contamination and mitigation
- COVID-19 and healthcare impacts
- Mental Health Treatment and Access
- Folate and B Vitamins Research
- Cardiovascular Health and Risk Factors
- Cardiovascular Function and Risk Factors
- Air Quality and Health Impacts
- Resilience and Mental Health
- Environmental Justice and Health Disparities
- Heavy metals in environment
- Biosensors and Analytical Detection
- Radiation Dose and Imaging
- SARS-CoV-2 detection and testing
- Aluminum toxicity and tolerance in plants and animals
- Employment and Welfare Studies
- Fluoride Effects and Removal
- Workplace Health and Well-being
- HIV-related health complications and treatments
- Biotechnology and Related Fields
Columbia University
2020-2025
Instituto Murciano de Investigación Biosanitaria
2021-2022
Hospital Universitario Virgen de la Arrixaca
2021
Universidad de Murcia
2021
Columbia University Irving Medical Center
2020
Abstract There is no safe level of exposure to inorganic arsenic or uranium, yet recent studies identified sociodemographic and regional inequalities in concentrations these frequently detected contaminants public water systems across the US. We analyze county-level association between racial/ethnic composition uranium from 2000–2011 using geospatial models. find that higher proportions Hispanic/Latino American Indian/Alaskan Native residents are associated with significantly concentrations....
BACKGROUND: Exposure to metals has been associated with cardiovascular disease (CVD) end points and mortality, yet prospective evidence is limited beyond arsenic, cadmium, lead. In this study, we assessed the association of urinary incident CVD all-cause mortality in a racially diverse population US adults from MESA (the Multi-Ethnic Study Atherosclerosis). METHODS: We included 6599 participants (mean [SD] age, 62.1 [10.2] years; 53% female) available at baseline (2000 2001) followed through...
Exposure to metals, a newly recognized risk factor for cardiovascular disease (CVD), could be related atherosclerosis progression.
Objective: To characterize the evolution of healthcare workers' mental health status over 1-year period following initial COVID-19 pandemic outbreak and to examine baseline characteristics associated with resolution or persistence problems time. Methods: We conducted an 8-month follow-up cohort study. Eligible participants were workers working in Spain. Baseline data collected during outbreak. Survey-based self-reported measures included COVID-19-related exposures, sociodemographic...
Importance Metals are established neurotoxicants, but evidence of their association with cognitive performance at low chronic exposure levels is limited. Objective To investigate the urinary metal levels, individually and as a mixture, tests dementia diagnosis, including effect modification by apolipoprotein ε4 allele ( APOE 4). Design, Setting, Participants The multicenter prospective cohort Multi-Ethnic Study Atherosclerosis (MESA) was started from July 2000 to August 2002, follow-up...
Despite the high burden of diabetes and cardiovascular risk factors in American Indian communities United States, prospective studies heart failure (HF) this population group are scarce, generalizability previous HF scales may be limited. We developed a parsimonious prediction equation that accounts for relevant affecting communities, focusing on kidney damage.
Background. Healthcare workers (HCWs) in COVID-19 pandemic hotspots were exposed to workplace stressors. Structural occupational factors that prevent stressor exposure from translating into mental health problems (i.e., resilience factors) remain poorly understood. This study identifies actionable at the and examines role of cumulative for developing depressive symptoms.Methods. We prospectively followed a convenience sample HCWs working Spain. used survey collect self-reported data on (a)...
Background: Environmental metals are recognized risk factors for cardiovascular disease, yet the role of urinary and metal mixtures on incident heart failure (HF) remains understudied. Objectives: To evaluate prospective association HF across three geographically ethnically/racially diverse cohorts: Multi-Ethnic Study Atherosclerosis (MESA) Strong Heart (SHS) in United States, Hortega cohort Spain. Methods: A total 6,644, 2,917, 1,334 adults 35-80 years old were included MESA (39%...
Growing evidence indicates that exposure to metals are risk factors for cardiovascular disease (CVD). We hypothesized higher urinary levels of with prior an association CVD, including non-essential (cadmium , tungsten, and uranium) essential (cobalt, copper, zinc) associated baseline rate change coronary artery calcium (CAC) progression, a subclinical marker atherosclerotic CVD.
Uranium is a potentially cardiotoxic, nonessential element commonly found in drinking water throughout the United States.
ObjectivesTo evaluate four sample treatments in a safe and straightforward procedure to detect SARS-CoV-2 saliva.MethodsFour were evaluated 3-step saliva: 1) heating at 95 °C for 5 min inactivation; 2) treatment; 3) analysis by reverse-transcription loop-mediated isothermal amplification (LAMP). Saliva samples used from infected individuals or spiked with known quantities of viral particles.ResultsThree had limit detection (LOD) 500.000 particles per ml saliva could be potential transmit the...
Introduction Although healthcare workers (HCWs) have reported mental health problems since the beginning of COVID-19 pandemic, they rarely use psychological support. Here, we described support among HCWs in Spain over 2-year period following initial pandemic outbreak and explore its association with workplace- COVID-19-related factors measured at baseline, 2020. Materials methods We conducted a longitudinal study on working Spain. used an online survey to collect information sociodemographic...
Inorganic arsenic is metabolized to monomethyl- (MMAs) and dimethyl- (DMAs) species via one-carbon metabolism (OCM); this facilitates urinary elimination. OCM influenced by folate vitamin B12 previous randomized control trials (RCTs) showed that folic acid (FA) supplementation increases methylation in adults. This RCT investigated the effects of FA + on children, a key developmental stage where supports growth.
Background: Environmental exposure to metals is widespread yet preventable and has been associated with cardiovascular disease (CVD) endpoints, although evidence from prospective studies racial ethnic diversity limited. Objective: We assessed the association of urinary incident coronary heart (CHD) CVD all-cause mortality in a diverse population adults Multi-Ethnic Study Atherosclerosis (MESA). Methods: included 6,638 MESA participants (mean (SD) age 62.1(10.2) years, 53% female, 39%...
Background: Urinary zinc has been associated with cardiometabolic endpoints including diabetes and peripheral artery disease (PAD), but evidence from prospective studies is limited. Objective: Our goal was to evaluate the association between urinary levels incident PAD amputation events in a large population-based cohort of American Indian adults US, Strong Heart Study (SHS) cohort. Methods: A total 2,049 PAD-free 2,184 amputation-free participants at baseline examination (1989-91) were...
Objective: Growing evidence indicates that exposure to metals are risk factors for cardiovascular disease (CVD). We hypothesized higher urinary levels of with prior an association CVD, including non-essential (cadmium , tungsten, and uranium) essential (cobalt, copper, zinc) associated baseline rate change coronary artery calcium (CAC) progression, a subclinical marker atherosclerotic CVD. Methods: analyzed data from 6,418 participants in the Multi-Ethnic Study Atherosclerosis (MESA) spot...