Imran Hussain

ORCID: 0000-0003-3177-4706
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About
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Research Areas
  • Phytochemistry and biological activities of Ficus species
  • Municipal Solid Waste Management
  • Cancer Genomics and Diagnostics
  • Natural Antidiabetic Agents Studies
  • Ethnobotanical and Medicinal Plants Studies
  • Flavonoids in Medical Research
  • Cancer-related Molecular Pathways
  • Fern and Epiphyte Biology
  • Hepatitis B Virus Studies
  • Cancer Cells and Metastasis
  • Healthcare and Environmental Waste Management
  • Plant and animal studies
  • Moringa oleifera research and applications
  • Lung Cancer Diagnosis and Treatment
  • BRCA gene mutations in cancer
  • Cancer, Hypoxia, and Metabolism
  • Microplastics and Plastic Pollution
  • AI in cancer detection
  • COVID-19 and healthcare impacts
  • Plant Diversity and Evolution
  • Poxvirus research and outbreaks
  • Rabies epidemiology and control
  • T-cell and B-cell Immunology
  • Vector-Borne Animal Diseases
  • Animal Virus Infections Studies

Integral University
2024

Henry M. Jackson Foundation
2023

Uniformed Services University of the Health Sciences
2017-2023

University of Balochistan
2023

Walter Reed National Military Medical Center
2018

Johns Hopkins Hospital
2018

National Institutes of Health
2018

Center for Cancer Research
2018

National Cancer Institute
2018

University of Minnesota
1993

Constitutive NF-κB activation (NF-κBCA) confers survival and proliferation advantages to cancer cells frequently occurs in T/B cell malignancies including adult T leukemia (ATL) caused by human T-cell virus type 1 (HTLV-1). Counterintuitively, NF-κBCA the HTLV-1 transactivator/oncoprotein Tax induces a senescence response, infections culture mostly result or cell-cycle arrest due How senescence, how ATL maintain avert remain unclear. Here we report that increases R-loop accumulation DNA...

10.1073/pnas.2005568118 article EN Proceedings of the National Academy of Sciences 2021-03-01

Summary The pathogenesis of hemorrhagic enteritis was investigated in 4‐week‐old specific‐pathogen‐free (SPF) turkeys after oral administration virus. virus antigen detected and quantified tissues at various days post‐infection (DPI) by an avidin‐biotin‐enhanced enzyme immunoassay located a monoclonal antibody‐based immunoperoxidase (IP) staining technique. In the intestinal tract, low levels viral were from 1 to 3 9 15 DPI, whereas high found 4 7 DPI. bursa had 2 plasma fraction blood...

10.1111/j.1439-0450.1993.tb00196.x article EN Journal of Veterinary Medicine Series B 1993-01-12

The present study was confined to pollen morphology and fertility estimation using a taxonomic description of 11 species genus Ficus family Moraceae. wereFicus bengalensis L, Ficus microcarpa L.f., Ficus palmata Forrsk., Ficus religiosa L., Ficus lacor Ham., pumila L., hispida L.f., Ficus sarmentosa Buch.Ham, Ficus auriculata Wall., virens Dryand. and Ficus racemosa Roxb. A palynomorphic the following conducted for first time not only in Asia, but worldwide. As such, no published details...

10.5897/jmpr.9000958 article EN Journal of Medicinal Plants Research 2011-09-30

Breast cancer has a lengthy history; the Egyptians were first to record cases of disease over 3500 years ago, around 1500 B.C. Worldwide, breast is most common and leading cause cancer-related deaths in women. Asia region responsible for 43% newly diagnosed 50% all globally. Lung no longer primary incidence worldwide; women surpassed it entirely, accounting 11.7% with projected 2.3 million new 2020. With prevalence 25.8 instances per 100,000 people, frequent India. In 2020, will be 13.6%...

10.36948/ijfmr.2024.v06i03.21946 article EN cc-by-sa International Journal For Multidisciplinary Research 2024-06-08

TP53 gene mutations are known to manifest in distinct p53 immunohistochemical staining patterns; overexpression, wild-type, and null. These stratified patterns routinely utilized subtyping ovarian cancer subtypes. Three cell lines were used the construction of an expression pattern control panel that highlight respective mutation status. The line sections demonstrated consistent clean easily interpretable staining. Procured resection, biopsy, cytologic specimens submitted along with either...

10.1097/pgp.0000000000000537 article EN International Journal of Gynecological Pathology 2018-07-19

Solid waste management (SWM) is a marginalized sector in Gilgit Baltistan, causing frightening situation, especially the municipal area of district Skardu. The total Skardu about 4260 sq. km with population approximately 112996. In line other government departments, Baltistan company (GBWMC) responsible for collecting and dumping solid waste. current study was devised to calculate, characterize, analyze past status, position (MSW) production, so that necessary practices corrective measures...

10.53560/ppasb(60-3)844 article EN cc-by Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences 2023-09-04

Abstract BACKGROUND: TP53 gene mutation status is known to be manifested through distinct p53 immunohistochemical staining patterns; diffuse, “wild-type” and null. This stratified pattern commonly utilized in subtyping ovarian endometrial cancer subtypes as well distinguishing between low- high-grade serous carcinoma. EXPERIMENTAL PROCEDURES: Three cell lines consistently demonstrating either wild-type or null were the construction of an control panel slide that highlights each expression...

10.1158/1557-3265.ovcasymp16-dpoc-002 article EN Clinical Cancer Research 2017-05-31

Abstract Hypoxia-inducible factor-1alpha (HIF-1α), a transcription factor important for maintaining cellular oxygen homeostasis, is aberrantly upregulated in many tumors and implicated angiogenesis, metastasis drug resistance. Therefore, developing treatments that target HIF-1α may be viable therapeutic approach. For centuries, traditional Chinese medicine has used herbs, such as Scutellaria baicalensis (SB), natural remedy tumors. However, the mechanisms by which SB inhibits tumor growth...

10.1158/1538-7445.am2017-1529 article EN Cancer Research 2017-07-01
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