L. Piersanti
A5043304173- Particle Accelerators and Free-Electron Lasers
- Radiation Therapy and Dosimetry
- Particle accelerators and beam dynamics
- Radiation Detection and Scintillator Technologies
- Radiation Effects in Electronics
- Gyrotron and Vacuum Electronics Research
- Nuclear Physics and Applications
- Laser-Plasma Interactions and Diagnostics
- Advanced Radiotherapy Techniques
- Quantum Information and Cryptography
- Superconducting and THz Device Technology
- Advanced X-ray Imaging Techniques
- Particle Detector Development and Performance
- Physics of Superconductivity and Magnetism
- Cold Atom Physics and Bose-Einstein Condensates
- Magnetic confinement fusion research
- Superconducting Materials and Applications
- Atomic and Subatomic Physics Research
- Quantum and electron transport phenomena
- Advanced Surface Polishing Techniques
- Pulsed Power Technology Applications
- Dark Matter and Cosmic Phenomena
- Quantum optics and atomic interactions
- Ion-surface interactions and analysis
- Medical Imaging Techniques and Applications
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati
2015-2024
Istituto Nazionale di Fisica Nucleare
2011-2023
University of Sannio
2022
University of Salerno
2022
Sapienza University of Rome
2011-2021
National Agency for New Technologies, Energy and Sustainable Economic Development
2020
Institut National de Physique Nucléaire et de Physique des Particules
2019
Université Paris-Saclay
2019
Université Paris-Sud
2019
Centre National de la Recherche Scientifique
2019
On the wake of results obtained so far at SPARC_LAB test-facility Laboratori Nazionali di Frascati (Italy), we are currently investigating possibility to design and build a new multi-disciplinary user-facility, equipped with soft X-ray Free Electron Laser (FEL) driven by ∼1 GeV high brightness linac based on plasma accelerator modules. This study is performed in synergy EuPRAXIA study. In this paper report about recent progresses going facility.
The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be for dose and Bragg peak monitoring to provide a fast feedback on treatment plans. Recent results obtained from authors simplified setups (mono-energetic primary beams interacting homogeneous tissue-like target) have already indicated correlation exists between flux of these secondaries coming target (e.g. protons photons) position beam peak. In...
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver emitter to tumor fundamental step in deployment such technique. This paper reports study uptake 90Y labeled (DOTATOC) meningioma and high grade glioma (HGG) feasibility RGS these cases.
The background induced by the high penetration power of radiation is main limiting factor current radio-guided surgery (RGS). To partially mitigate it, a RGS with β(+)-emitting radio-tracers has been suggested in literature. Here we propose use β(-)-emitting and β(-) probes discuss advantage this method respect to previously explored ones: electron low allows for simple versatile could extend tumours which originating from nearby healthy tissue makes less effective. We developed probe...
The development of compact accelerator facilities providing high-brightness beams is one the most challenging tasks in field next-generation and cost affordable particle accelerators, to be used many fields for industrial, medical, research applications. ability shape beam longitudinal phase space, particular, plays a key role achieving high-peak brightness. Here we present new approach that allows us tune space by means plasma wakefields. electron passing through drives large wakefields are...
Plasma-based technology promises a tremendous reduction in size of accelerators used for research, medical, and industrial applications, making it possible to develop tabletop machines accessible broader scientific community. By overcoming current limits conventional pushing particles larger energies, the availability strong tunable focusing optics is mandatory also because plasma-accelerated beams usually have large angular divergences. In this regard, active-plasma lenses represent compact...
Abstract CompactLight is a Design Study funded by the European Union under Horizon 2020 research and innovation funding programme, with Grant Agreement No. 777431. was conducted an International Collaboration of 23 international laboratories academic institutions, three private companies, five third parties. The project, which started in January 2018 duration 48 months, aimed to design innovative, compact, cost-effective hard X-ray FEL facility complemented soft source pave road for future...
Organic scintillators are often chosen as radiation detectors for their fast decay time and low Z, while inorganic ones used when high light yields required. In this paper we show that a para-terphenyl based detector has blend of properties the two categories can be optimal energy position measurements low-energy charged particles. Using 0.1% diphenylbutadiene doped samples measured attenuation length λ = 4.73 ±0.06 mm, quenching factor α particles Q <sub...
The breakthrough provided by plasma-based accelerators enabled unprecedented accelerating fields boosting electron beams to gigaelectronvolt energies within a few centimeters [1-4]. This, in turn, allows the realization of ultracompact light sources based on free-electron lasers (FELs) [5], as demonstrated two pioneering experiments that reported observation self-amplified spontaneous emission (SASE) driven plasma-accelerated [6,7]. However, lack stability and reproducibility due intrinsic...
Charged particle beams are used in therapy (PT) to treat oncological patients due their selective dose deposition tissues with respect the photons and electrons conventional radiotherapy. Heavy (Z > 1) PT can additionally be exploited for high biological effectiveness killing cancer cells. Nowadays, protons carbon ions clinical routines. Recently, interest potential application of helium oxygen has been growing. With protons, such characterized by reduced multiple scattering inside body,...
The generation of ultra-short electron bunches with ultra-low timing-jitter relative to the photo-cathode (PC) laser has been experimentally proved for first time at SPARC_LAB test-facility (INFN-LNF, Frascati) exploiting a two-stage hybrid compression scheme. stage employs RF-based (velocity-bunching), which shortens bunch and imprints an energy chirp on it. second is performed in non-isochronous dogleg line, where completed resulting final duration below 90 fs (rms). At same time, beam...
In this paper, we report the use of a superconducting transmon qubit in 3D cavity for quantum machine learning and photon counting applications. We first describe realization characterization coupled to resonator, providing detailed description simulation framework experimental measurement important parameters, such as dispersive shift anharmonicity. then on Quantum Machine Learning application implemented single-qubit device fit u-quark parton distribution function proton. final section...
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles.To meet the improved capability hadrontherapy matching dose release with position, new monitoring techniques need to be developed and introduced into clinical use.The measurement fluxes secondary particles produced by hadron beam fundamental importance design any device eagerly needed tune Monte Carlo simulations.We report measurements done from interaction a 80 MeV/u fully stripped carbon ion at...
The INSIDE project addresses the online dose monitoring in particle therapy issue.The proposed detectors exploit secondary neutral and charged particles emitted during treatment by irradiated volumes.The new detection techniques allow to return a measurement of released Bragg peak position.
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring dose delivered during such treatments still a matter research. A possible exploits information provided by single photon emission from nuclear decays induced irradiation. This paper reports measurements spectrum rate photons produced interaction 80 MeV/u fully stripped beam at Laboratori Nazionali del Sud INFN, Catania, with Poly-methyl methacrylate target. differential production...
Proton and carbon ion beams are used in the clinical practice for external radiotherapy treatments achieving, selected indications, promising superior results with respect to x-ray based radiotherapy. Other ions, like have recently been considered as projectiles particle therapy centres might represent a good compromise between linear energy transfer radiobiological effectiveness of proton beams, allowing improved tumour control probability minimising normal tissue complication probability....
Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained by the use of $^4$He projectiles. Unlike performed using protons, beam ions can undergo fragmentation process when interacting with atomic nuclei patient body. this paper measurements at Heidelberg Ion-Beam center reported. For first time absolute fluxes...
Abstract Reducing noise to the quantum limit over a large bandwidth is fundamental requirement for future applications operating at millikelvin temperatures, such as neutrino mass measurement, next-generation X-ray observatory, CMB dark matter and axion detection, rapid high-fidelity readout of superconducting qubits. The read out sensitivity arrays microcalorimeter detectors, resonant axion-detectors, qubits, currently limited by temperature cryogenic amplifiers. Detector Array Readout with...
This study presents recent advancements in Josephson Traveling Wave Parametric Amplifiers (JTWPAs) developed and tested at INRiM within the DARTWARS project framework. Combining junctions with superconducting coplanar waveguides, JTWPAs offer advanced capabilities for quantum-limited broadband microwave amplification emission of non-classical radiation. The work delves into architecture, optimization, experimental characterization a JTWPA Resonant Phase-Matching mechanism, highlighting...