A5087913047- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Lymphatic System and Diseases
- Breast Implant and Reconstruction
- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- Cancer survivorship and care
- BRCA gene mutations in cancer
- Body Contouring and Surgery
- Patient-Provider Communication in Healthcare
- Cancer Treatment and Pharmacology
- Diagnosis and Treatment of Venous Diseases
- Systemic Sclerosis and Related Diseases
- Estrogen and related hormone effects
- HER2/EGFR in Cancer Research
- Cancer Genomics and Diagnostics
- Body Composition Measurement Techniques
- Male Breast Health Studies
- Cancer and Skin Lesions
- Lymphoma Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Sympathectomy and Hyperhidrosis Treatments
- Colorectal Cancer Screening and Detection
- Advances in Oncology and Radiotherapy
- Lung Cancer Treatments and Mutations
Macquarie University
2015-2024
Sydney Adventist Hospital
2020-2024
Australian National University
2022-2024
ACT Government
2023
Government of Western Australia Department of Health
2022-2023
Cancer Australia
2023
National Cancer Centre Japan
2021
Okayama University
2019
Morpho (United States)
2019
John Wiley & Sons (United States)
2019
Previous studies of patients with infiltrating ductal breast cancer treated conservative surgery (ie, limited excision) and radiotherapy have indicated that the presence an extensive intraductal component (EIC) in excision specimen is highly associated subsequent recurrence. The reason for this association not clear, but possible explanations include more disease or increased radiation resistance among tumors EIC (EIC+) compared those without (EIC-) tumors. To investigate further, we related...
Arm lymphedema following breast cancer surgery is a continuing problem. In this study, we assessed the reliability and validity of circumferential measurements water displacement for measuring upper-limb volume.Participants included subjects who had surgery, including axillary dissection--19 with 22 without diagnosis arm lymphedema--and 25 control subjects.Two raters measured each subject by using tape at specified distances from fingertips in relation to anatomic landmarks displacement....
Management of patients with ductal carcinoma in situ (DCIS) is a dilemma, as mastectomy provides nearly 100% cure rate but at the expense physical and psychologic morbidity. It would be helpful if we could predict which DCIS are sufficiently high risk local recurrence after conservative surgery (CS) alone to warrant postoperative radiotherapy (RT) sufficient CS + RT mastectomy. The authors reviewed published studies identified factors that may predictive management by mastectomy, alone, or...
Abstract Little is known of the psychosocial factors associated with decision regret in context breast reconstruction following mastectomy for cancer treatment. Moreover, there a paucity theoretically‐based research area post‐decision regret. Adopting theoretical framework Monitoring Process Model ( Cancer 1995; 76 (1):167–177), current study assessed role information satisfaction, psychological distress and moderating effect monitoring coping style to experience over undergo reconstructive...
The identification of multiple tumors in the breast is associated with increased nodal involvement when compared similar staged unifocal disease. This study compares two methods tumor size assessment to predict behavior relationship between and axillary node for patients multifocal multicentric cancer.The histologic reports every patient cancer treated New South Wales April 1995 September were examined. Tumors assessed using estimates: (1) largest focus diameter (2) aggregate diameters all...
Purpose Breast cancer treatment adverse effects result in one three survivors experiencing body image–related distress (BID) that negatively impacts on a woman’s ability to recover after and into survivorship. My Changed Body (MyCB) is Web-based psychological intervention alleviate BID improve appreciation of breast (BCSs) through single-session, self-compassion focused writing activity. This randomized controlled trial evaluated the impact MyCB BCSs. The moderating effect lymphedema status...
This research describes and evaluates a liposuction surgery multidisciplinary rehabilitation approach for advanced lymphedema of the upper lower extremities.A prospective clinical study was conducted at an Advanced Lymphedema Assessment Clinic (ALAC) comprised specialists in plastic surgery, rehabilitation, imaging, oncology, allied health, Macquarie University, Australia. Between May 2012 31 2014, total 104 patients attended ALAC. Eligibility criteria included (i) unilateral, non-pitting,...
Objective Our study examines the financial cost of lymphedema following a diagnosis breast cancer and addresses significant knowledge gap regarding additional impact on survivors. Methods An online national survey was conducted with 361 women who had either without (BC) (group 1, n = 209) or (BC+LE) 2, 152). Participant recruitment supported by Breast Cancer Network Australia Australasian Lymphology Association. Results Both result in out-of-pocket costs borne women. Of patients BC+LE, 80%...
Background: This study compared rates of progression to chronic breast cancer-related lymphedema (defined as ≥ 10% arm volume change from baseline requiring complex decongestive physiotherapy [CDP]) following an intervention for subclinical (S-BCRL) triggered by bioimpedance spectroscopy (BIS) or tape measurement (TM). Methods and Results: stratified, randomized, international trial enrolled new cancer patients undergoing: mastectomy/partial mastectomy, axillary treatment (dissection,...
Abstract BACKGROUND Breast conservative surgery (CS) with radiotherapy (RT) is the most commonly used treatment for early‐stage breast carcinoma. However, there controversy regarding importance of pathologic margin status on risk ipsilateral tumor recurrence (IBTR). The current study evaluated effect IBTR rates in a cohort women lymph node‐negative carcinoma treated CS and RT. METHODS Between August 1980 December 1994, 452 pathologically were RT at Westmead Hospital (Westmead, Australia)....
Background: The objectives of the present study were to evaluate incidence and predictors axillary lymph node metastases (ALNM) in patients with breast cancer, identify if surgery could be safely omitted selected patients. Methods: Between January 1996 May 2000, 492 underwent 501 dissections (ALND). ALNM was correlated clinical pathological characteristics by univariate multivariate analyses. Results: Axillary found 41% (207/501) cases. Univariate analysis showed that palpability primary...
Our study examines the impact of breast cancer-related lymphedema on women's work and career. research addresses a significant knowledge gap regarding additional cancer survivors. An online national survey was conducted with 361 women who either had without (Group 1, n = 209) or 2, 152). Participant recruitment supported by Breast Cancer Network Australia Australasian Lymphology Association. Both negative influence Respondents reported changes in employment resulting from stress and/or...
Background Bioimpedance spectroscopy (BIS) has enabled the early identification of breast cancer‐related lymphedema. In this study, differences in health service metrics and incidence lymphedema are evaluated an surveillance model care compared with a traditional referral care. Methods retrospective analysis data from 753 women who underwent BIS measures between January 1, 2007 December 31, 2016, 188 were assigned to “early surveillance” group if they began monitoring presurgery (n = 121) or...
Deciding whether or not to have breast reconstruction following cancer diagnosis is a complex decision process. This randomized controlled trial assessed the impact of an online aid [Breast RECONstruction Decision Aid (BRECONDA)] on decision-making.Women (n = 222) diagnosed with ductal carcinoma in situ, and eligible for mastectomy, completed baseline questionnaire. They were then assigned randomly receive either standard information about (control) plus access BRECONDA (intervention)....
Background Most lymphatic imaging examinations of the lower limb require intradermal or subcutaneous injection tracer material into foot to demonstrate vessels; however, no standard protocol exists, and single multiple injections are applied at different sites. Purpose To determine three-dimensional relationships between each group corresponding regional lymph nodes. Materials Methods A total 130 limbs (55 from men 75 women) 83 fresh human cadavers were studied. Lymphatic vessels first...
Breast cancer-related lymphedema (BCRL) represents a major source of morbidity among breast cancer survivors. Increasing data support early detection subclinical BCRL followed by intervention. A randomized controlled trial is being conducted comparing progression rates using volume measurements calculated from the circumference tape measure (TM) or bioimpedance spectroscopy (BIS). Patients were enrolled and to either TM BIS surveillance. requiring intervention prescribed compression sleeve...
Abstract Background Breast cancer related lymphoedema (BCRL) is a common side effect of treatment. Recently indocyanine green (ICG) fluorescent lymphography has become popular method for imaging the lymphatics, however there are no standard protocols nor criteria. We have developed prospective protocol to aid in diagnosis and therapeutic management BCRL. Methods Lymphatic procedures were conducted three phases. Following initial observation spontaneous movement ICG phase one, manual...
Background To evaluate risk factors (treatment‐related, comorbidities, and lifestyle) for breast cancer–related lymphedema (BCRL) within the context of a Prospective Surveillance Early Intervention (PSEI) model care subclinical BCRL. Methods The parent randomized clinical trial assigned patients newly diagnosed with cancer to PSEI either bioimpedance spectroscopy (BIS) or tape measurement (TM). Surgical, systemic radiation treatments, lifestyle were recorded. Detection BCRL (change from...
This study investigated the influence of psychosocial and surgical factors on decision regret among 123 women diagnosed with breast cancer who had undergone immediate (58%) or delayed (42%) reconstruction following mastectomy. The majority participants (52.8%, n = 65) experienced no regret, 27.6% mild 19.5% moderate to strong regret. Bivariate analyses indicated that was associated negative body image psychological distress - intrusion avoidance. There were differences in either respect...