Layanne Nascimento Fraga

ORCID: 0000-0003-3208-5048
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About
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Research Areas
  • Agricultural and Food Sciences
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry Medicinal Plant Applications
  • Banana Cultivation and Research
  • Antioxidant Activity and Oxidative Stress
  • Microbial Metabolites in Food Biotechnology
  • Sensory Analysis and Statistical Methods
  • Tea Polyphenols and Effects
  • Polysaccharides and Plant Cell Walls
  • Pancreatic function and diabetes
  • Diet, Metabolism, and Disease
  • Food Safety and Hygiene
  • Genomics, phytochemicals, and oxidative stress
  • Food, Nutrition, and Cultural Practices
  • Food Quality and Safety Studies
  • Pharmacogenetics and Drug Metabolism
  • Healthcare and Environmental Waste Management
  • Food Waste Reduction and Sustainability
  • Public Health in Brazil
  • Metabolomics and Mass Spectrometry Studies
  • Plant biochemistry and biosynthesis
  • Metabolism, Diabetes, and Cancer
  • Natural Antidiabetic Agents Studies
  • Ginseng Biological Effects and Applications
  • Diabetes Treatment and Management

Universidade de São Paulo
2019-2025

Instituto de Ciências Farmacêuticas
2023

Hospital Universitário da Universidade de São Paulo
2020

Universidade Federal de Sergipe
2017-2020

Large interindividual variations in the biological response to citrus flavanones have been observed, and this could be associated with high their bioavailability. The aim of study was identify main determinants underlying differences flavanone metabolism excretion. In a randomized cross-over study, non-obese obese volunteers, aged 19-40 years, ingested single doses Pera Moro orange juices, urine collected for 24 h. A large difference recovery urinary phase II metabolites hesperetin-sulfate...

10.3390/nu13020473 article EN Nutrients 2021-01-30

ABSTRACT There has been concern regarding the consumption of fruit juices because high levels naturally occurring sugars they contain, which could rapidly elevate glycaemic response and increase risk cardiometabolic diseases. We conducted two trials in each volunteer ingested (1) white bread with 200 mL types orange juice prepared from ‘Moro’ ‘Pera’ varieties (MOJ POJ) – former containing anthocyanins same alone; (2) POJ or MOJ followed by a sandwich made bread, plus light cheese butter,...

10.1017/s0007114525000418 article EN other-oa British Journal Of Nutrition 2025-03-17

Brazilian native fruits are excellent sources of polyphenols, especially berries, which rich in anthocyanins. These compounds associated with improvements the insulin signaling pathway, reduced glucose absorption, and...

10.1039/d4fo03749a article EN Food & Function 2025-01-01

Citrus fruits and juices are a major source of dietary flavanones, the regular consumption these foods is inversely associated with development cardiometabolic diseases. However, biological benefits depend on bioavailability compounds, previous studies have reported large interindividual variability in absorption excretion compounds. Different factors, such as age, gender or genetic polymorphism genes coding enzymes involved metabolism transport may explain this heterogeneity. This study...

10.3390/nu14183770 article EN Nutrients 2022-09-13

Chronic orange juice intake is associated with reduced risk of cardiovascular disease, however, a large inter-individual variability in response to for lipid profile and blood pressure has been observed. This heterogeneity responsiveness could be single nucleotide polymorphism (SNP), which not previously addressed. study aims investigate the influence SNP apolipoprotein E (APOE), A1 (APOA1), mevalonate (MVK), lipase lipoprotein (LPL) genes biological after chronic intake.Forty-six volunteers...

10.1002/mnfr.202200847 article EN Molecular Nutrition & Food Research 2023-05-02

Talisia esculenta (A. ST.-HIL.) Radlk is a Brazilian wild fruit, known as pitomba, belonging to the Sapindaceae family. The objective of present work was perform review literature in order identify studies on its physico-chemical characterization, antioxidant activity and biological activity. articles search done PubMed, SciELO, Science Direct LILACS. We identified 90 publications, 8 3 LILACS, 67 12 PubMed. Subsequently, duplication between databases verified, triage by reading titles,...

10.33448/rsd-v9i2.1909 article EN Research Society and Development 2019-11-27

No âmbito das Unidades de Alimentação e Nutrição Hospitalares (UANSs) há produção resíduos que são descartados durante a refeições. Foi realizado um estudo transversal para levantamento práticas sustentabilidade quatorze UANs hospitalares capital brasileira situa na região Nordeste. Para tanto foi aplicado questionário digital aos nutricionistas responsáveis pelas UANs, abordou aspectos sobre gestão, controle no consumo água, energia, prática coleta seletiva resíduos, descarte óleos...

10.29183/2447-3073.mix2020.v6.n3.45-54 article PT cc-by MIX Sustentável 2020-06-18

Citrus flavanones may improve oxidative stress and insulin resistance induced by western diets. However, there is a paucity of studies investigating the change in protein expression levels. This study evaluated protection mechanisms action citrus flavanone metabolites, hesperetin 7-glucuronide (H7G) 3-(4'-hydroxyphenyl) propanoic acid (PA), on pancreatic β-cell function under cholesterol using global proteomics approach. Cholesterol changes proteomic profile line Min6. On other hand,...

10.1039/d2fo02479a article EN Food & Function 2022-01-01

This study aimed to evaluate the physico-chemical composition and bioactive compounds of pulp peel pitomba arising from state Sergipe/Brazil. The income, characterization, mineral content, vitamin C carotenoids were determined. presented high income (44,60% fruit). A significant amount (20,68 ± 2,93 mg/100g fresh sample) (43,56 2,04 μg/mL extract) observed in pulp, while had a mainly potassium (223,00 2,00 mg/100g), calcium (78,90 0,40 mg/100g) magnesium (47,50 0,90 mg/100g). constituents’...

10.33448/rsd-v9i1.1774 article EN Research Society and Development 2019-10-28

Abstract It is well known that dietary fibers (DF) from plant-source foods can induce beneficial health effects through their physicochemical properties and utilization by the gut microbiota during fermentation, which mainly explored with a focus on changes in profile production of microbial-derived metabolites. Here, we characterized structural motifs (i.e., oligomers) produced DF breakdown upon colonic fermentation interaction toll-like receptors (TLRs) present surface human intestinal...

10.1101/2024.09.13.612858 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-14

Introdução: No âmbito hospitalar, a alimentação e nutrição têm o objetivo de restaurar saúde dos pacientes, disponibilizando aporte essencial adequado nutrientes. Objetivo: Analisar perfil recursos humanos em serviços suas possíveis implicações no contexto da segurança alimentar unidades produtoras refeições hospitalares na cidade Aracaju, Sergipe. Método: Foi aplicado um questionário semiestruturado, buscando informações acerca caracterização organização funcional das avaliadas. O estudo...

10.33448/rsd-v9i10.8115 article PT Research Society and Development 2020-09-17

Introduction: By assuming adequate food as a social right, the Brazilian State became bearer of duty to respect, provide, promote and protect Human Right Adequate Food (HRAF) for all Brazilians, including celiacs. Therefore, it is essential that institute normative apparatus compatible with needs celiac population, guaranteeing fulfillment their rights. Objective: assess whether legislation in force Brazil meets demands people disease. Methods: document analysis was adopted according...

10.33448/rsd-v11i9.31742 article EN Research Society and Development 2022-07-12
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