- Oral and Maxillofacial Pathology
- Oral Health Pathology and Treatment
- HIV/AIDS oral health manifestations
- Oral and gingival health research
- Tumors and Oncological Cases
- Bone Tumor Diagnosis and Treatments
- Head and Neck Surgical Oncology
- Oral microbiology and periodontitis research
- Head and Neck Cancer Studies
- Dental Education, Practice, Research
- Endodontics and Root Canal Treatments
- Hedgehog Signaling Pathway Studies
- Skin Diseases and Diabetes
- Dental Health and Care Utilization
- dental development and anomalies
- Psidium guajava Extracts and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer-related gene regulation
- Cell death mechanisms and regulation
- Biological Stains and Phytochemicals
- Infective Endocarditis Diagnosis and Management
- Otolaryngology and Infectious Diseases
- Natural Compounds in Disease Treatment
- Vascular Malformations and Hemangiomas
- Teratomas and Epidermoid Cysts
University of Nairobi
2012-2025
Ministry of Health
2014
University of Bergen
2003
The mouth and oropharynx are among the ten most common sites affected by cancer worldwide, but global incidence varies widely. Five-year survival rates exceed 50% in only best treatment centers. Causes predominantly lifestyle-related: Tobacco, areca nut, alcohol, poor diet, viral infections, pollution all important etiological factors. Oral is a disease of dispossessed, reducing social inequalities requires national policies co-ordinated with wider health initiatives - risk factor approach:...
A bstract : Khat is the Celastraceus edulis plant, a flowering evergreen tree or large shrub, which grows in Horn of Africa and southwestern Arabia. use has been associated with development oral cancer, but its molecular effects remain controversial. This study describes novel cytotoxic effect whole khat extract on three leukemia cell lines. Cells were exposed to harvested for analysis by fluorescent electron microscopy, trypan blue exclusion, as well immunoblotting characterize mode death....
Objective: To characterize the diagnostic features of ossifying fibroma (OF) and fibrous dysplasia (FD) jaw bones. Study Design: A histopathological radiological analysis with full clinical documentation. Setting: University Nairobi Dental Teaching Hospital (UNDH). Population: All archival cases diagnosed as FD OF from 1992-2006 were retrieved UNDH Oral Pathology Laboratory records. New included they pre-sented over a 6-month period January to June 2007. Methodology: Information regarding...
A number of factors have been cited as determinants for choosing a career in dentistry around the globe. The purpose this study was to determine motivations among dental students and interns Kenya. This cross-sectional where 293 individuals participated by filling returning self-administered questionnaires. mean age all respondents 22.3 years. Overall, 59.5% had selected their preferred at end high school. Majority (76.1%) agreed that personal interest an important motivating factor them....
Background Better knowledge and skills for diagnosis management of human immunodeficiency virus (HIV) related oral lesions by primary healthcare workers (PHWs) may increase recognition HIV-related (HROLs) improve implementation HIV testing in Kenya. For this purpose training programs at health facility community level were evaluated. Design Methods A pre-post control-test group design two administrative divisions Nairobi East District was used. Clinical competencies PHWs (n = 32...
This study endeavors to bridge the long-term diagnostic and management gap through a comprehensive audit of odontogenic cysts tumors in Kenya, offering crucial insights for both clinicians policymakers.
Abstract Background Periodontitis has been associated with adverse pregnancy outcomes. Little is known about the burden and risk factors for periodontitis among reproductive age women in sub-Saharan Africa. This analysis aimed to determine prevalence correlates of Kenyan planning conceive. Methods HIV-seronegative, reproductive-age who were conceive enrolled underwent a periodontal examination. Following US Centers Disease Control Prevention clinical case definitions, presence severity was...
Salivary gland tumours (SGT) are rare, comprising about 5% of head and neck with a higher incidence reported in the western compared African centres. There few studies on SGTs that have been conducted Africa. A descriptive retrospective study was done to describe demographic characteristics, site distribution histological patterns SGT at University teaching hospital Kenya over 12-year-duration. were 132 out 2426 biopsies tumours, age range between 8 80 years (mean = 43.6 yrs) modal 50 yrs....
Human immunodeficiency virus (HIV) related orofacial lesions (HROLs) impact negatively on the health of patients and could be managed at primary healthcare (PHC) level. Community workers (CHWs) are crucial in optimal patient management through identification, education early referral for professional care. The study objective was to assess knowledge Nairobi East district CHWs regarding HROLs other common oral diseases. Of total population CHWs, 815 [94.5%] completed a 56-item questionnaire...
Objective: To determine the clinico-histopathologic variations and etiological factors associated with oral squamous cell carcinoma (OSCC). Methods: A descriptive cross-sectional hospital based study was conducted at University of Nairobi Dental Hospital (UNDH) Kenyatta National (KNH) between September 2008 February 2009. Eighty-two (82) patients presenting lesions confirmed as OSCC were evaluated for habits identified risk such tobacco use, alcohol use betel quid chewing. Demographic...
The highest burden of diseases worldwide is in low- and middle-income countries, but due to lack capacity inadequate infrastructure, research output from these countries unable address existing emerging challenges health care. Oral has particularly been hampered by low prioritization, resulting insufficient development this sector. There an urgent need for correlating oral upstream social environmental determinants promoting the common risk factor approach prevention noncommunicable...
Background:In the Kenya primary health care (PHC) setting where most patients, including nearly 1.4 million HIV-infected people, seek medical care, PHC providers are expected to identify and manage HIV-related oral diseases during general consultations.This study aimed assess
Background: Jaw cysts and cyst-like lesions cause facial deformity, destruction of dental tissues affect masticatory phonation functions. These ad-versely erode patients’ psycho-social status; create low self-esteem may change one’s identity appearance. Objective: To determine the histo-pathologic characteristics, variants demographic pattern jaw at University Nairobi Dental Hospital. Material Me-thod: This was an analytical verification study that involved microscopic re-examination all...
Background: Orofacial infections are either odontogenic or non-odontogenic in nature. The clinical spectrum of these is diverse. This study aimed to describe the presentation and management patients presenting with orofacial at Kenyatta National Hospital (KNH).
 Materials Methods: was a retrospective based on records treated for bacterial KNH fromJanuary 2016 December 2018. Data following variables were obtained analyzed: demographic data, presentation, diagnosis, management, treatment...
Aim: The aim of this study is to determine the antimicrobial efficacy aqueous and ethanol extracts Euclea divinorum Hiern against some root canal microorganisms compared conventional irrigants. Settings Design: An in vitro laboratory at University Nairobi. Materials Methods: E. branches were collected, dried, ground into coarse powder. filtrates lipolyzed while reduced under vacuum oven-dried Growth inhibition cell cultures from pure strains Enterococcus faecalis ( ATCC® 29212™ ),...
A case is presented of a 15-year-old boy who manifested the calcifying cystic odontogenic tumour (CCOT) in left maxillary antrum an unknown duration. In addition, patient had high arched palate and multiple impacted teeth normal series supernumerary type including mesiodens as demonstrated orthopantomograph.
Uptake of various dental specialties does vary globally. There is scarce information regarding motivations and preferences for in developing countries.
 Aims objectivesThis study aimed to determine perceptions, factors that influence specialty choice Kenya.
 Design methods
 This was a cross-sectional among students interns conducted at two schools inKenya. It census used self-administered questionnaires collect information. 
 ResultsMost (76%) participants indicated...