Chinedum Amara Onebunne

ORCID: 0000-0003-3220-0093
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About
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Research Areas
  • Maternal and fetal healthcare
  • Maternal and Perinatal Health Interventions
  • Reproductive tract infections research
  • Urinary Tract Infections Management
  • Pelvic floor disorders treatments
  • Blood donation and transfusion practices
  • Homicide, Infanticide, and Child Abuse
  • Adolescent Sexual and Reproductive Health
  • Preterm Birth and Chorioamnionitis
  • Cervical Cancer and HPV Research
  • Global Maternal and Child Health
  • Organ Donation and Transplantation
  • Gut microbiota and health
  • Ovarian cancer diagnosis and treatment
  • Grief, Bereavement, and Mental Health
  • Reproductive Health and Contraception

University College Hospital, Ibadan
2018-2021

University College Hospital
2020

University College London
2020

Preterm birth (PTB) is the largest contributor to infant death in sub-Saharan Africa and globally. With a global estimate of 773,600, Nigeria has third highest rate PTB worldwide. There have been number microbiome profiling studies identify vaginal microbiomes suggestive preterm healthy outcome. However, on pregnancy are sparse with none performed Nigeria. Moreover, few considered concurrent impact steroid hormones We assessed two key determinants progression gain deeper understanding...

10.1128/msphere.01261-20 article EN cc-by mSphere 2021-02-02

Abstract Steroid hormones are one of the presumed modulators Lactobacillus abundance in vaginal epithelium. We set out to characterize microbiome (VMB) and also provide an in-depth understanding relative contribution estradiol (E2) progesterone (P1) shaping Nigerian women (n = 38) who experienced both uncomplicated term delivery preterm using samples longitudinally collected during pregnancy (17–21, 27–31, 36–41 weeks gestation) 6 postpartum. Vaginal swabs blood were aseptically collected....

10.1038/s41598-021-96339-y article EN cc-by Scientific Reports 2021-09-13

Objectives: To assess the prevalence of unwanted pregnancies and induced abortion among female undergraduates.Methodology: A cross-sectional survey was conducted undergraduates in University Ibadan, Nigeria. The used a structured, self-administered questionnaire. Data analysis using Statistical Package for Social Sciences version 20 with Chi-square t-tests. significance set at P < 0.05.Findings: mean age participants 20.3 (±2.7) years 80% were single time study. 51%. overall pregnancy 17%,...

10.4103/tjog.tjog_35_19 article EN Tropical Journal of Obstetrics and Gynaecology 2019-01-01

Background: Antepartum haemorrhage (APH) as one of the major obstetric emergencies contributing greatly to maternal and fetal morbidity mortality is serious concern in developing world. A retrospective analysis APH cases evaluation its impact on outcomes was conducted.Methods: study managed between January 2013 December 2014 at University College Hospital Ibadan; all a minimum 28 weeks gestation with antepartum bleeding were selected. Data retrieved from hospital records.Results: Around 5.8%...

10.18203/2320-1770.ijrcog20193017 article EN International Journal of Reproduction Contraception Obstetrics and Gynecology 2019-06-29

Background: Noncommunicable diseases are increasing in proportion developing countries. Ovarian cancer has the highest case fatality rate among gynecological cancers but forms only 3%. Its etiology is unknown, and no cost-effective screening program exists due to absence of well-defined precursor lesions. Early symptoms vague can be used detect Stages I II diseases. Documented knowledge or awareness ovarian varies between 4.4% 15%. However, this first community-based survey Africa determine...

10.4103/jncd.jncd_31_17 article EN cc-by-nc-sa International Journal of Noncommunicable Diseases 2018-01-01

Background : The vaginal microbiota is an important component of the reproductive health women as it offers protection against urogenital infection. African are reported to have a colonized with high proportions strict anaerobes rather than lactobacillus - dominated microbes. These been associated pre-term birth and neonatal disease. prevalence pre- term (PTB) in Africa poses major challenge healthcare, hence clinical scientific attention focused on understanding causative mechanisms PTB. A...

10.21106/ijma.330 article EN cc-by International Journal of Maternal and Child Health and AIDS 2020-02-18

Background&#x0D; Successful vaginal delivery (VD) is the desire of every parturient. This however not always so especially for primigravid women. Predictive factors can help counselling process and allay anxiety that this group parturients experience.&#x0D; Objective&#x0D; To determine prevalence predictors among women at a tertiary health facility.&#x0D; Methods&#x0D; was 6-month cross-sectional study 200 were planned delivery. Information obtained using structured proforma. Bivariate...

10.4314/rjmhs.v4i1.3 article EN cc-by-nc-nd Rwanda Journal of Medicine and Health Sciences 2021-04-08

The placenta has been used in different facets of medicine however some low-income countries are yet to apply these uses for reasons. A cross-sectional study 150 expectant mothers attending antenatal clinic was conducted determine the willingness donate placenta. Analysis using Statistical Package Social Sciences version 20 with a level significance set at P ≤ .05. mean age participants 32.3 (SD±5.0) years. Almost all (98.7%) were married while 89.3% had tertiary-level education. majority...

10.1080/03630242.2021.2002998 article EN Women & Health 2021-11-22
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