A5081655856- Cardiac tumors and thrombi
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Immune responses and vaccinations
- Nonmelanoma Skin Cancer Studies
- Pancreatitis Pathology and Treatment
- Infectious Diseases and Mycology
- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer and Skin Lesions
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Spondyloarthritis Studies and Treatments
- Brain Metastases and Treatment
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Musculoskeletal synovial abnormalities and treatments
- Parkinson's Disease Mechanisms and Treatments
- Eosinophilic Disorders and Syndromes
- Epigenetics and DNA Methylation
- Glioma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- Mitochondrial Function and Pathology
- Amyotrophic Lateral Sclerosis Research
Lund University
2017-2023
Hospital Universitari Germans Trias i Pujol
2014-2018
Universitat Autònoma de Barcelona
2016-2018
A wide range of neurological manifestations have been associated with the development COVID-19 following SARS-CoV-2 infection. However, etiology symptomatology is still largely unexplored. Here, we used state-of-the-art multiplexed immunostaining human brains (n = 6 COVID-19, median age 69.5 years; n 7 control, 68 years) and demonstrated that expression receptor ACE2 restricted to a subset neurovascular pericytes. Strikingly, symptoms were exclusive to, ubiquitous in, patients exhibited...
Abstract Background Every actinic keratosis ( AK ) starts with atypia at the basal layers of epidermis I). Progression into invasive squamous cell carcinoma iSCC may occur following two main pathways, classical and differentiated. In former, only occurs after involvement upper epidermal by atypical cells III ), while in latter develops directly from I. anogenital mucosa, these pathways are associated differential expression p53 p16. Objective To explore differences between both pathogenesis...
Abstract A wide range of neurological manifestations have been associated with the development COVID-19 following SARS-CoV-2 infection. However, etiology symptomatology is still largely unexplored. Here, we used state-of-the-art multiplexed immunostaining human brains ( n = 6 COVID-19, median age 69,5 years; and 7 control, 68 years), demonstrated that expression receptor ACE2 restricted to a subset neurovascular pericytes. Strikingly, symptoms were exclusive to, ubiquitous in, patients...
Actinic keratosis (AK) may show extension down follicles, not only in cases with full-thickness epidermal atypia ('bowenoid' AK), but also limited to the basalis. Previous studies have demonstrated that, bowenoid AK, follicular is usually superficial, being upper segment. Little known about depth of involvement invasive squamous cell carcinoma skin (iSCC) arising from AK and role follicle iSCC pathogenesis.This study investigated relationship between atypical keratinocytes an development...
ABSTRACT Severe Coronavirus disease 2019 (COVID-19) induces heterogeneous and progressive diffuse alveolar damage (DAD) highly disrupting lung tissue architecture homeostasis, hampering management leading to fatal outcomes. Characterizing DAD pathophysiology across progression is of ultimate importance better understand the molecular cellular features driving different patterns optimize treatment strategies. To contextualize interplay between cell types assess their distribution, spatial...
A common trait amongst severely affected patients with COVID-19 is lung damage and respiratory failure, the most cause of death.1Milross L. Majo J. Cooper N. et al.Post-mortem tissue: fossil record pathophysiology immunopathology severe COVID-19.Lancet Respir Med. 2022; 10: 95-106Abstract Full Text PDF PubMed Scopus (31) Google Scholar,2Bridges J.P. Vladar E.K. Huang H. al.Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19.Thorax. 77: 203-209Crossref (83) Scholar In addition,...
There are few studies on the locus coeruleus (LC) in frontotemporal lobar degeneration (FTLD) and potential differences LC related to underlying proteinopathy.The aim of this study was investigate FTLD subgroups.Neuropathological cases diagnosed with were included. The subgroups consisted tau, transactive response DNA-binding protein 43 (TDP) fused sarcoma (FUS). Micro- macroscopical assessed respect number neurons degree depigmentation. A group cognitively healthy subjects a vascular...
<h3>Background</h3> Systemic vasculitis (SV) comprises a group of diseases characterized by inflammation vessels in various organs. Histopathological confirmation is required for the diagnosis. The biopsy an involved organ invasive and carries risk complications. By contrast, gastrocnemius muscle simple minimally technique that may be performed rheumatologist. <h3>Objectives</h3> To evaluate diagnostic use biopsies diagnosis SV. <h3>Methods</h3> Retrospective study 1984 - 2015. Center:...