Ling Yang

ORCID: 0000-0003-3240-9751
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Research Areas
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Metabolism, Diabetes, and Cancer
  • Vitamin D Research Studies
  • Fibroblast Growth Factor Research
  • Adipose Tissue and Metabolism
  • Pharmacological Effects of Natural Compounds
  • Growth Hormone and Insulin-like Growth Factors
  • Innovations in Medical Education
  • Epigenetics and DNA Methylation
  • Diet, Metabolism, and Disease
  • Cardiac pacing and defibrillation studies
  • Diabetes Treatment and Management
  • Healthcare and Venom Research
  • Cardiac Arrhythmias and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Nitric Oxide and Endothelin Effects
  • Polysaccharides and Plant Cell Walls
  • Online Learning and Analytics
  • Cancer-related molecular mechanisms research
  • Acupuncture Treatment Research Studies
  • Advanced Technologies in Various Fields
  • Cholesterol and Lipid Metabolism
  • Receptor Mechanisms and Signaling
  • Colorectal Cancer Treatments and Studies

Affiliated Hospital of Jiangsu University
2006-2024

Jiangsu University
2006-2024

Sixth Affiliated Hospital of Kunming Medical University
2015-2024

Kunming Medical University
2015-2024

Wuxi Third People's Hospital
2024

Army Medical University
2020-2023

Hunan Mawangdui Hospital
2012

Betatrophin, a newly identified hormone, has been recently characterized as potent stimulator that increases the production and expansion of insulin-secreting β-cells in mice, but physiological role betatrophin remains poorly understood. This study measured for first time serum levels diagnosed patients with type 2 diabetes (T2DM) explored correlations between its various metabolic parameters T2DM.We analyzed concentrations by ELISA blood samples 166 well-characterized individuals whom...

10.2337/dc14-0602 article EN Diabetes Care 2014-07-15

Oxytocin can affect energy homeostasis and has interesting potential as a metabolic disease therapeutic. We detected serum oxytocin levels in obese (OB) type 2 diabetes mellitus (T2DM) subjects investigated the relationships between glycolipid metabolism, insulin resistance, pancreatic β-cell function, inflammation.A total of 176 were enrolled study, including 88 patients with newly diagnosed T2DM normal glucose tolerance (NGT). NGT groups divided into normal-weight (NW) OB subgroups....

10.1210/jc.2014-2206 article EN The Journal of Clinical Endocrinology & Metabolism 2014-09-18

Abstract Background Lipid metabolism imbalance has been recognized as one of the major drivers impaired glucose in context type 2 diabetes mellitus (T2DM), rates which are steadily increasing worldwide. Impaired regulation (IGR) plays a vital role prevention and treatment T2DM. The goal this study was to further clarify whether combination plant sterols (PS) omega-3 fatty acids yields any synergistic effect that enhances IGR. Methods A total 200 participants were randomized receive PS ( n =...

10.1186/s12944-019-1048-x article EN cc-by Lipids in Health and Disease 2019-05-01

Platinum-based chemotherapies, historically the cornerstone of first-line treatment for small-cell lung cancer (SCLC), face a major hurdle: frequent emergence chemoresistance, notably to cisplatin (CDDP). Current understanding mechanisms driving CDDP resistance in SCLC is incomplete. Notably, Interferon inducible transmembrane protein1 (IFITM1) has been identified as key player distant metastasis SCLC. Analysis The Cancer Genome Atlas (TCGA) database revealed that IFITM1 expression markedly...

10.1016/j.heliyon.2024.e30806 article EN cc-by-nc-nd Heliyon 2024-05-01

We detected whether serum asprosin levels play a role in the occurrence and development of albuminuria patients with type 2 diabetes mellitus (T2DM), which has not been previously discussed.Based on urinary albumin/creatinine ratio (UACR), 207 T2DM were divided into normoalbuminuria (UACR<30 mg/g), microalbuminuria (30≤UACR<300 macroalbuminuria (UACR≥300 mg/g). Serum determined by enzyme-linked immunosorbent assay.Comparatively, patient groups [2.37 (1.63-3.57)] [2.10 (1.60-2.90)]...

10.2147/dmso.s283413 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2020-11-01

Insulin resistance and/or insulin secretion dysfunction are crucial causes of type 2 diabetes mellitus (T2DM). Although some studies have suggested potential roles for vitamins D and K in glucose metabolism sensitivity, there is limited inconclusive research on their levels T2DM patients relationship with blood resistance. Additionally, a lack large-scale clinical trials comprehensive investigating the combined effects T2DM.

10.3389/fendo.2024.1412228 article EN cc-by Frontiers in Endocrinology 2024-07-15

Background: This study was conducted in patients with type 2 diabetes mellitus (T2DM) to assess the association between visceral fat area (VFA) and cardiac hemodynamics. Methods: A total of 568 (mean age 54± 12 years; 40.8% women) were enrolled. Visceral (VFA, m ) subcutaneous (SFA, evaluated by a bioelectrical impedance analyzer. Cardiac hemodynamics measured echocardiography, other clinical laboratory variables also assessed recorded. Patients divided into those VFA ≤ 100 (n=369) >...

10.2147/dmso.s284420 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2020-11-01

This study aimed to quantitatively summarize the evidence for VDR BsmI gene polymorphism and osteoporosis risk in postmenopausal women. The PubMed, EMBASE, Weipu, CNKI, Wanfang databases were searched eligible studies. Case-control studies containing available genotype frequencies of B/b chosen, odds ratio (OR) with 95% confidence interval (CI) was used assess strength this association. 4485 5490 controls identified our meta-analysis. In stratified analysis, a significant association...

10.1186/s12263-020-00679-9 article EN cc-by Genes & Nutrition 2020-11-25

Background: Data comparing active atrial lead fixation with passive in Chinese patients cardiovascular implantable electronic devices (CIEDs) for pacing is limited. Our study evaluated the effectiveness of versus leads by observing performance parameters.Methods: This retrospective, long-term, single-center included a cohort who underwent CIED implantation at Department Cardiology People’s Hospital Yuxi City, China, from 1 March 2010 to 2015. Efficacy was determined time, threshold values,...

10.1080/03007995.2016.1275938 article EN Current Medical Research and Opinion 2016-12-24

To observe the influence of repeated shallow fire-needle acupuncture stimulation plus cupping on local neuralgia and serum substance P(SP)content in patients with acute herpes zoster (AHZ).A total 60 cases AHZ were randomly divided into control (medication) group treatment (medication fire-needle) (n=30 each). Patients both groups ordered to take Famciclovir (0.25 g/time, three times a day) Mecobalamin (0.5 orally for 7 days. In addition, also treated by cupping, once day Before after...

10.13702/j.1000-0607.170923 article EN PubMed 2018-08-25

Massive Open Online Courses (MOOCs) are a new phenomenon in education worldwide. In China, MOOCs have been widely used medical courses. However, the effects of on improving clinical skills controversial. Therefore, we conducted study to verify whether application courses can improve participants' China. A systematic literature search was carried out using PubMed, Embase, Web Science, CNKI and Wanfang databases according predetermined criteria. The Hedges' g its corresponding 95% confidence...

10.1016/j.heliyon.2023.e19263 article EN cc-by-nc-nd Heliyon 2023-08-01

Angiopoietin-like protein 8 (ANGPTL8), a newly identified hormone, has been recently characterized as metabolic regulator which can affect energy homeostasis and interesting potentials disease therapy. However, little is yet known to whether circulating ANGPTL8 levels are altered in thyroid dysfunction. This study measured serum patients with Graves' explored the correlations between its index disease. The concentration of was analyzed blood samples 128 well-characterized individuals whose...

10.1007/s42000-019-00095-8 article EN cc-by HORMONES 2019-03-21

Over the past few decades, recent developments in pacemaker technology from fixed-rate single-chamber pacemakers to dual chamber with pacing algorithms have changed therapeutic landscape resulting better healthcare outcomes by improving rate response minimal ventricular pacing. Here, we share our longest clinical experience an elderly Chinese male patient who was diagnosed third-degree atrioventricular (AV) block and admitted hospital 33 years ago. An 85-year-old China hospitalized due...

10.3978/j.issn.2305-5839.2015.11.35 article EN PubMed 2015-12-01

Abstract Background Acute herpes zoster (AHZ) is a common skin disease caused by invasion of the varicella virus into ganglia and skin, severe pain most complaint, which can seriously disturb normal life patients. Fire needle plus cupping special acupuncture treatment, widely used to treat AHZ for its better analgesic effect in China although it has not been fully verified rigorous randomized controlled trial (RCT). Methods/design To test effect, three-arm parallel protocol designed. A total...

10.1186/s13063-020-04599-2 article EN cc-by Trials 2020-08-06
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