A5061264896- Radiomics and Machine Learning in Medical Imaging
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- MRI in cancer diagnosis
- Cerebral Venous Sinus Thrombosis
- COVID-19 diagnosis using AI
- Renal and Vascular Pathologies
- Advanced Neuroimaging Techniques and Applications
- Long-Term Effects of COVID-19
- RNA modifications and cancer
- Nanoplatforms for cancer theranostics
- COVID-19 Clinical Research Studies
- Pregnancy and Medication Impact
- Renal Diseases and Glomerulopathies
- Cancer Research and Treatments
- Adrenal and Paraganglionic Tumors
- Pancreatic and Hepatic Oncology Research
- Bladder and Urothelial Cancer Treatments
- Advanced MRI Techniques and Applications
- Sarcoma Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Cancer-related molecular mechanisms research
Second Affiliated Hospital of Nanchang University
2025
Nanchang University
2025
Fudan University
2016-2025
Huashan Hospital
2016-2025
Zhejiang Chinese Medical University
2024
Beijing Hospital of Traditional Chinese Medicine
2024
Capital Medical University
2024
Sichuan University
2009-2021
West China Hospital of Sichuan University
2004-2021
Zhengzhou University
2018-2021
BackgroundIncreasing evidence supported the possible neuro-invasion potential of SARS-CoV-2. However, no studies were conducted to explore existence micro-structural changes in central nervous system after infection. We aimed identify brain related SARS-CoV-2.MethodsIn this prospective study, diffusion tensor imaging (DTI) and 3D high-resolution T1WI sequences acquired 60 recovered COVID-19 patients (56.67% male; age: 44.10 ± 16.00) 39 age- sex-matched non-COVID-19 controls (56.41% 45.88...
PIWI-interacting RNAs are a class of small that is most abundantly expressed in animal germline. Substantial research going on to reveal the functions piRNAs epigenetic and post-transcriptional regulation transposons genes. To collect annotate these data, we developed piRBase, database assisting piRNA functional study. Since its launch 2014, piRBase has integrated 264 data sets from 21 organisms, number collected reached 173 million. The latest release (v2.0, 2018) was more focused...
The facultative intracellular bacterium Listeria monocytogenes (Lmo) has great potential for development as a cancer vaccine platform given its properties. However, the clinical application of Lmo been severely restricted due to rapid clearance, compromised immune response in tumors, and inevitable side effects such severe systemic inflammation after intravenous administration. Herein, an immunotherapy system was developed on basis natural red blood cell (RBC) membranes encapsulated with...
The transcription factor hypoxia-inducible factor-1alpha (HIF-1alpha) plays pivotal roles in physiology and pathophysiology. Constitutive or hypoxia-induced HIF-1alpha overexpression is observed many types of cancers including prostate adenocarcinoma, which it associated with resistance to apoptosis therapeutic agents. BCL-xL, a hypoxia-responsive, anti-apoptotic protein the Bcl-2 family, also overexpressed carcinoma other cancers. Despite this connection, whether BCL-xL expression directly...
Objective To investigate the role of quantitative analysis T2 relaxation time in magnetic resonance imaging (MRI) diagnosis breast cancer. Methods The study enrolled patients with clinical masses who were examined using MRI at eight different echo times. differences benign and malignant lesions analysed. Results A total 67 (67 lesions: 46 malignant, 21 benign) examined. mean ± SD was significantly lower compared (82.69 15.37 ms versus 95.48 26.51 ms, respectively). area under curve 0.731....
Tumor-targeted immunotherapy is a remarkable breakthrough, offering the inimitable advantage of specific tumoricidal effects with reduced immune-associated cytotoxicity. However, existing platforms suffer from low efficacy, inability to induce strong immunogenic cell death (ICD), and restrained capacity transforming immune-deserted tumors into immune-cultivated ones. Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO2 nanoparticles (MBP), was developed...
OBJECTIVE: The purpose of our study was to investigate the predictive abilities clinical and computed tomography (CT) features for outcome prediction in patients with coronavirus disease (COVID-19). MATERIALS AND METHODS: CT data 238 laboratory-confirmed COVID-19 two hospitals were retrospectively analyzed. One hundred sixty-six (103 males; age 43.8 ± 12.3 years) allocated training cohort 72 (38 45.1 15.8 from another independent hospital assigned validation cohort. primary composite...
<title>Abstract</title> <bold>Background and Objectives</bold> The incidence of complications following pancreaticoduodenectomy (PD) is notably high. Early postoperative abdominal lavage has been suggested as a potential intervention to reduce these complications. This study explores the safety efficacy self-made double-lumen drainage tube by comparing after PD using different tubes. <bold>Methods</bold> A retrospective was conducted analyze clinical data patients who underwent at our...
Background Falcine sinuses can remain persistent after birth, but they also become recanalized in cases where venous are invaded by meningiomas. Purpose To explore the incidence and imaging features of falcine healthy individuals parasagittal meningioma (PSM) patients on magnetic resonance venography (MRV). Material Methods Radiologists evaluated data 168 PSM patients. The invasion extent superior sagittal sinus (SSS) PSMs was confirmed a neurosurgeon based Sindou's criteria. We compared...
The purpose of this retrospective review is to determine the MR imaging features pilocytic astrocytoma (PA) in spinal cord help neuroradiologists preoperatively differentiate PA from other intramedullary tumors. Neuro-oncology database revealed 13 consecutive patients with a pathological diagnosis and availability preoperative imaging. Three had diffusion-weighted Demographics conventional diffusion records were retrospectively evaluated. Among cases PA, six PAs located cervical region, 4...
Objective: This study aimed to investigate the evolution of radiological findings in patients with coronavirus disease 2019 (COVID-19) pneumonia different severities from onset 1-year follow-up and identify predictive factors for pulmonary lesion absorption status infected COVID-19. Methods: A retrospective was performed on clinical features 175 COVID-19 hospitalized at three institutions January 21 March 20, 2020. All chest CT scans during hospitalization follow-ups after discharge were...