A5100715780- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Peanut Plant Research Studies
- Advanced Memory and Neural Computing
- Advanced Algorithms and Applications
- Ferroelectric and Negative Capacitance Devices
- Cancer-related molecular mechanisms research
- Polymer composites and self-healing
- Circular RNAs in diseases
- Lignin and Wood Chemistry
- Graphene research and applications
- Graphene and Nanomaterials Applications
- Coconut Research and Applications
- Bone Tissue Engineering Materials
- Electronic and Structural Properties of Oxides
- Hydrocarbon exploration and reservoir analysis
- Innovative Educational Techniques
- Hydraulic Fracturing and Reservoir Analysis
- Tendon Structure and Treatment
- Advanced Battery Technologies Research
- Boron and Carbon Nanomaterials Research
- Advanced Battery Materials and Technologies
- Synthetic Aperture Radar (SAR) Applications and Techniques
Changchun University of Science and Technology
2025
Dalian University of Technology
2025
Sir Run Run Shaw Hospital
2017-2024
Zhejiang University
2017-2024
Yangzhou University
2024
Xiamen University
2010-2024
Shenyang Pharmaceutical University
2016-2024
Huanggang Central Hospital
2024
Baoding People's Hospital
2024
Jinchuan (China)
2023
High-performance lignin-containing polyurethane elastomers (LPUes) were successfully synthesized via partially substituting petroleum-derived polyols with depolymerized enzymatic hydrolysis lignin (DEL). The influences of DEL on the structure, thermostability, mechanical performance, and thermal reprocessability LPUes systematically studied. tensile strength toughness PUes significantly enhanced after introduction DEL, maximum reaching up to 60.7 MPa 263.6 MJ/m3. enhancement for was...
CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and upregulated in osteosarcoma cell lines, but its functional role still unknown. This study aimed to clarify the mechanism circMYO10 osteosarcoma.CircMYO10 expression 10 paired chondroma tissues was assessed quantitative reverse transcription polymerase chain reaction (PCR). The function circMYO10/miR-370-3p/RUVBL1 axis regarding two key characteristics: proliferation endothelial-mesenchymal transition (EMT)....
Highly resilient lignin-containing polyurethane (PU) foam was synthesized via using alkali lignin as a partial substitute for the petrochemical polyols. The flexible polyethylene glycol chains were first grafted onto lignin, converting phenolic hydroxyls on to aliphatic and enhancing reaction activity of lignin. influence modified-lignin structure, mechanical properties thermal stability PU foams analyzed. provided flexibility foams. All exhibited large elastic recovery higher than 93%....
Inflammatory responses of nucleus pulposus (NP) can induce imbalanced anabolism and catabolism extracellular matrix, the cytosolic dsDNA accumulation STING-NF-κB pathway activation found in NP inflammation are considered as fairly important cause intervertebral disc (IVD) degeneration. Herein, we constructed a siSTING delivery hydrogel aldehyde hyaluronic acid (HA-CHO) poly(amidoamine) PAMAM/siRNA complex to intervene abnormal STING signal for IVD degeneration treatment, where formation...
A critical-sized bone defect, which cannot be repaired through self-healing, is a major challenge in clinical therapeutics. The combination of biomimetic hydrogels and nano-hydroxyapatite (nano-HAP) promising way to solve this problem by constructing an osteogenic microenvironment. However, it challenging generate nano-HAP with similar morphology structure that natural bone, limits the improvement regeneration hydrogels. Inspired our previous works on organic-inorganic cocross-linking, here,...
The lethality and chemotherapy resistance of pancreatic cancer necessitates the urgent development innovative strategies to improve patient outcomes. To address this issue, we designed a novel drug delivery system named GDMCN2,which uses iron-based metal organic framework (Fe-MOF) nanocages encased in covalent (COF) modified with cancer-specific antibody, NRP2. After being targeted into tumor cells, GDMCN2 gradually release sonosensitizer sinoporphyrin sodium (DVDMS) chemotherapeutic...
Abstract Tendon to bone (enthesis) rupture, which may cause disability and persistent pain, shows high rate of re‐rupture after surgical repair. or enthesis scaffolds have been widely studied, but few these materials can recapitulate the tissue continuity. Thus, this study is conducted prepare a triphasic decellularized bone‐fibrocartilage‐tendon (D‐BFT) composite scaffold. The D‐BFT scaffold developed using combination physical, chemical, enzymatic treatments liquid nitrogen, Triton‐X 100,...
Tumor-targeted immunotherapy is a remarkable breakthrough, offering the inimitable advantage of specific tumoricidal effects with reduced immune-associated cytotoxicity. However, existing platforms suffer from low efficacy, inability to induce strong immunogenic cell death (ICD), and restrained capacity transforming immune-deserted tumors into immune-cultivated ones. Here, an innovative platform, perfluorooctyl bromide (PFOB) nanoemulsions holding MnO2 nanoparticles (MBP), was developed...
High-efficiency nanotheranostic agents with multimodal imaging guidance have attracted considerable interest in the field of cancer therapy. Herein, novel silver-decorated bismuth-based heterostructured polyvinyl pyrrolidone nanoparticles (NPs) good biocompatibility (Bi-Ag@PVP NPs) were synthesized for accurate theranostic treatment, which can integrate computed tomography (CT)/photoacoustic (PA) and photodynamic therapy/photothermal therapy (PDT/PTT) into one platform. The Bi-Ag@PVP NPs...
Abstract Accidental trauma is always accompanied by tissue defects with noncompressible hemorrhages. Deformable and tough biomaterials are desirable for self‐compressible hemostasis, although their preparation challenging. Here, a critical‐size calcium phosphate (C–CaP) polymer‐like high deformability mineral‐like bending strength prepared, which hybridized silk fibroin (SF) to fabricate hemostatic sponge (SF‐C). C–CaP endows SF‐C an ultrahigh elastic modulus (36.0 kPa) among analogous...
Diagnosis and prognosis of tumorigenesis are generally performed with CT, PET, or biopsy. Such methods accurate, but have the limitations high cost posing additional health risks to patients. In this study, we introduce an alternative computer aided diagnostic tool that can locate malignant sites caused by in a non-invasive low-cost way. Our hypothesis is exhaled aerosol distribution unique lung structure sensitive airway variations. With appropriate approaches, it possible disease site,...
Amine-based CO2 capture is a promising method to limit global emissions. However, large thermal energy consumption for desorption during amine regeneration has limited large-scale worldwide applications. Here, we show that an efficient MCM-41-SO3H-0.6 catalyst presented superior catalytic performance, decreasing the relative heat duty by one-third and enhancing instantaneous rate up 195% in comparison with monoethanolamine (MEA) without catalysts. The excellent activity related combination...
Road damage detection is crucial for ensuring road safety and minimizing maintenance costs. However, detecting small damage, managing complex backgrounds, identifying irregular shapes remain significant challenges. To address these issues, we propose YOLO-RD, an advanced framework that integrates innovative modules feature enhancement, multi-scale robustness, detail preservation. Specifically, the Star Operation Module (SOM) improves sensitivity to small-scale Multi-dimensional Auxiliary...