The lung clearance index (LCI) is more sensitive than spirometry in detecting abnormal function children with cystic fibrosis. LCI thought to be independent of age, but recent evidence suggests that the upper limit normal higher infants and preschool older subjects. This study examines whether remains body size throughout childhood. Multiple-breath washout data from healthy adolescents were collated three centres using mass spectrometer system inert gas sulfur hexafluoride. Reference...

Abstract Background The most recent demographic data reveal that only 6.5% of practicing orthopaedic surgeons are women, and as far we know, two women have held chair positions in academic programs the United States. Furthermore, surgery is least gender-diverse speciality recognized by Accreditation Council for Graduate Medical Education. factors contribute to lack gender diversity orthopaedics remain ill-defined. A lag publication productivity may be a barrier career advancement surgeons,...

SUMMARY Effects of body position and type ventilation were determined on arterial blood gases (Pa O 2 , Pa CO ) pH during immediately following clinical halo-thane anesthesia in 36 young, physically conditioned horses. Horses dorsal recumbency had a lower than did similarly breathing horses lateral position. Predictably controlled positive-pressure improved oxygenation permitted maintenance normal . Most horses, regardless operative positioning, hypoxemic the immediate postanesthetic period.

This study examined whether beetroot juice (BTJ) would attenuate inflammation and muscle damage following a marathon. Using double blind, independent group design, 34 runners (each having completed ca. ∼16 previous marathons) consumed either BTJ or an isocaloric placebo (PLA) for 3 days Maximal isometric voluntary contractions (MIVC), countermovement jumps (CMJ), soreness, serum cytokines, leucocytosis, creatine kinase (CK), high sensitivity C-reactive protein (hs-CRP), aspartate...

Abstract Tart Montmorency cherry concentrate (MC) has been reported to attenuate the symptoms of exercise‐induced muscle damage (EIMD) and accelerate exercise recovery, which attributed its high anti‐inflammatory antioxidant properties. Although these data are promising, there no regarding exclusively female populations. Therefore, aim this investigation was examine efficacy MC on recovery following EIMD in females. In a randomised, double‐blind, placebo‐controlled study, twenty physically...

Elite ballet dancers are at risk of health issues associated with Relative Energy Deficiency in Sport (RED-S). This study determined the nutritional status, estimated energy and assessed factors related to RED-S vocational female students. Using a cross-sectional design, we measured dietary intake (food diaries 24 h dietary-recall) expenditure (accelerometry) students (n = 20; age: 18.1 ± 1.1 years; body mass index: 19.0 1.6 kg·m2; fat: 22.8 3.4%) over 7 days, including 5 weekdays (with...

Many athletes in aesthetic and weight dependent sports are at risk of energy imbalance. However little is known about the exercise eating behaviours highly trained dance populations. This investigation sought to determine intake expenditure pre-professional female contemporary dancers. Twenty-five students completed study. Over a 7-day period, including five week days (with scheduled training conservatoire) two weekend no conservatoire), (self-reported weighed food diary 24 h dietary recall)...

A number of different forms protein and their analogues have been investigated for efficacy in ameliorating exercise-induced muscle damage (EIMD) recovery. Preliminary data regarding whey hydrolysate (WPH) supplementation are promising. However, its beyond acute eccentric/resistance exercise bouts or longer term training programmes limited all investigations conducted male mixed-sex groups. This study sought to elucidate whether the benefits WPH previously reported can be demonstrated...

Abstract Along with the well-known rewarding effects, activation of nicotinic acetylcholine receptors (nAChRs) can also relieve pain, and some agonists have analgesic efficacy similar to opioids. A major target drugs is descending pain modulatory pathway, including ventrolateral periaqueductal gray (vlPAG) rostral ventromedial medulla (RVM). Although activating nAChRs within this circuitry be analgesic, little known about subunit composition cellular effects these receptors, particularly...

Importance The conflict in Ukraine has forced civilian hospitals with limited trauma and battlefield medicine experience to care for casualties of war, placing significant strain on the health system. Using Checklist Early Recognition Treatment Acute Illness Injury (CERTAIN) program, a multimodal critical knowledge-exchange platform was created clinicians practicing these institutions. Objectives To describe development implementation CERTAIN program evaluate reach this intervention,...

Introduction: Heparin-induced thrombocytopenia (HIT) is an autoimmune life-threatening prothrombotic syndrome associated with low platelet count after heparin exposure. Spontaneous heparin-induced (S-HIT) even less frequent variant of HIT, only a handful reports available in the literature, where unexplained and/or thrombosis without recent exposure occurs setting positive anti-PF4 antibodies. Case Presentation: We report case S-HIT pulmonary artery embolism, left internal jugular vein, and...

The protein tomosyn decreases synaptic transmission and release probability of vesicles, is essential for modulating in neurons. In this study, we provide a detailed description the expression localization patterns tomosyn1 tomosyn2 subareas mouse hippocampus. Using confocal two-photon high-resolution microscopy, show tomosyn1's differential distribution hippocampus, concentrated mainly hilus mossy fibers. Tomosyn colocalizes with several pre- postsynaptic markers found glutamatergic...

Objective: To evaluate the occurrence of hypothalamic-pituitary dysfunction following a traumatic brain injury (TBI) and to determine its effect on functional improvement in acute inpatient rehabilitation. Methods: A retrospective chart review identified male patients with primary diagnosis TBI or without skull fracture, an onset date within 6 months prior admission, were 16 years age older. The percentage individuals this population abnormal hormone levels was determined basis established...

This study was designed to assess the effect of a dairy-based recovery beverage on post-exercise appetite and energy intake in active females. Thirteen females completed three trials crossover design. Participants 60 min cycling at 65% V̇O2peak, before 120 period. On completion cycling, participants consumed commercially available (DBB), carbohydrate (CHO), or water control (H2O). Non-esterified fatty acids, glucose, appetite-related peptides alongside measures subjective were sampled...

Independently, prolonged uninterrupted sitting and the consumption of a meal high in saturated fats acutely disrupt normal cardiovascular function. Currently, acute effects these behaviors performed combination on arterial stiffness, marker health, are unknown. This study sought to determine effect consuming high-fat (Δ = 51 g fat) conjunction with (180 min) measures central peripheral stiffness. Using randomized crossover design, 13 young healthy males consumed (61 g) or low-fat (10 before...

This study examined whether consuming casein protein (CP) pre-sleep could accelerate acute recovery following muscle-damaging exercise. Thirty-nine active males and females performed 100 drop jumps in the morning, consumed their habitual diet during day, then within 30 min pre-bed either ~40 g of CP (n = 19) or a carbohydrate-only control (CON) 20). Maximal isometric voluntary contractions (MIVC), countermovement (CMJ), pressure-pain threshold (PPT), subjective muscle soreness brief...

Abstract Brown, MA, Howatson, G, Keane, KM, and Stevenson, EJ. Adaptation to damaging dance repeated-sprint activity in women. J Strength Cond Res 30(9): 2574–2581, 2016—The repeated bout effect (RBE) refers the prophylactic from exercise after a single previous of exercise. There is paucity data examining RBE women, investigations using paradigms beyond isolated eccentric contractions are scarce. In light limited literature, this investigation aimed determine whether 2 different...

INTRODUCTION There is growing interest in gender equity medicine. Despite increasing representation, disparity academia still persists.1-3 Inequities authorship and visibility within medicine remain prevalent.2,4 Publications participation at academic meetings are used as measures of career advancement recognition.5 Obstacles research funding, publications, presentation impair faculty appointments for women.2,6 They less likely to attain senior ranks.4,7 Women the minority panelists...

Implant-based breast reconstruction in postmastectomy patients is commonly performed a submuscular plane. Following reconstruction, animation deformity can be displeasing aesthetic result for patients. In addition, may experience more postoperative pain with reconstruction. Prepectoral conversion of implant position an option addressing these concerns. We describe detailed technique and review our results.A retrospective was conducted all prepectoral conversions by the senior author (DSW)...

Prolonged uninterrupted sitting and a typical Western meal, high in fat refined sugar, can additively impair cognitive cerebrovascular functions. However, it is unknown whether interrupting these behaviours, with simple desk-based activity, attenuate the impairment. The aim of this study was to determine regular leg fidgeting off-set detrimental effects prolonged following consumption on executive function. Using randomized cross-over design, 13 healthy males consumed meal completed 180-min...