A5087529596- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
- Nutritional Studies and Diet
- Sodium Intake and Health
- Blood Pressure and Hypertension Studies
- Consumer Attitudes and Food Labeling
- Botanical Research and Applications
- Vitamin C and Antioxidants Research
- Nitric Oxide and Endothelin Effects
- Cardiovascular Health and Disease Prevention
- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
- Pomegranate: compositions and health benefits
- Diet and metabolism studies
- Pharmacology and Obesity Treatment
- Neurological Disorders and Treatments
- Fatty Acid Research and Health
- Adipokines, Inflammation, and Metabolic Diseases
- Neurological Disease Mechanisms and Treatments
- Microbial Metabolites in Food Biotechnology
- Biochemical Analysis and Sensing Techniques
- Tea Polyphenols and Effects
- Hormonal Regulation and Hypertension
- Free Radicals and Antioxidants
- Phytoestrogen effects and research
Transnational Press London
2020
King's College London
2006-2020
University of Reading
2006-2016
Northumbria University
2006-2016
Unité de Nutrition Humaine
2011-2015
Frimley Park Hospital
2012-2014
Food & Nutrition
2011
New York University Press
2010
Cambridge University Press
2010
University of Limerick
2006
We have investigated the bacterial-dependent metabolism of ( − )-epicatechin and (+)-catechin using a pH-controlled, stirred, batch-culture fermentation system reflective distal region human large intestine. Incubation or (150 mg/l 1000 mg/l) with faecal bacteria, led to generation 5-(3′,4′-dihydroxyphenyl)-γ-valerolactone, 5-phenyl-γ-valerolactone phenylpropionic acid. However, formation these metabolites from required its initial conversion (+)-epicatechin. The both flavanols occurred in...
There are very limited data regarding the effects of blueberry flavonoid intake on vascular function in healthy humans.We investigated impact endothelial men and assessed potential mechanisms action by assessment circulating metabolites neutrophil NADPH oxidase activity.Two randomized, controlled, double-blind, crossover human-intervention trials were conducted with 21 men. Initially, flow-mediated dilation (FMD) polyphenol absorption metabolism was at baseline 1, 2, 4, 6 h after consumption...
A number of vegetables have a high nitrate content which after ingestion can be reduced to nitrite by oral bacteria, and further vasoprotective NO endogenously. In the present study, two separate randomly controlled, single-blind, cross-over, postprandial studies were performed in normotensive volunteers. Ambulatory blood pressure (BP) was measured over 24 h period following consumption either four doses beetroot juice (BJ), 0, 100, 250 500 g ( n 18), or three bread products, control (0...
Scope Blueberries are a rich source of flavonoids and phenolic acids. Currently, little information is available regarding the impact processing on bioavailability bioactivity blueberry (poly)phenols. Methods results In randomized, controlled crossover trial, ten healthy volunteers consumed (a) blueberry‐containing baked products, (b) an unprocessed drink containing same amount freeze‐dried powder as used in (c) matched control products. Endothelial function was measured flow‐mediated...
Accumulating evidence suggests that diets rich in (poly)phenols may have positive effects on human health. Currently there is limited information regarding the of processing (poly)phenolic content berries, particular processes related to baking industry. This study investigated impact cooking, proving, and anthocyanin, procyanidin, flavonol, phenolic acid contents wild blueberry using HPLC with UV fluorescence detection. Anthocyanin levels decreased during baking, whereas no significant...
Covering: February 1996 to December 1998. Continuing the coverage in Contemporary Organic Synthesis, 1997, 4, 435.
Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of CVD. However, Champagne has not been fully investigated for its cardioprotective potential. In order to assess whether acute moderate is capable modulating vascular function, we performed a randomised, placebo-controlled, cross-over intervention trial. We show that wine, but control matched alcohol, carbohydrate fruit-derived acid content, induced change in endothelium-independent...
Abstract Background Fruit and vegetable‐rich diets are associated with a reduced cardiovascular disease ( CVD ) risk. This protective effect may be result of the phytochemicals present within fruits vegetables F&V ). However, there can considerable variation in content phytochemical composition whole depending on growing location, cultivar, season agricultural practices, etc. Therefore, study investigated effects consuming as puree‐based drinks FVPD daily vasodilation, bioavailability,...
The average UK adult consumes less than three portions of fruit and vegetables daily, despite evidence to suggest that consuming five daily could help prevent chronic diseases. It is recommended juice should only count as one these portions, juicing removes fibre releases sugars. However, juices contain beneficial compounds such vitamin C flavonoids be a useful source dietary phytochemicals. Two randomised controlled cross-over intervention studies investigating the effects acute consumption...
Epidemiological studies indicate that diets rich in fruits and vegetables (F&V) are protective against CVD. Puréed F&V products retain many beneficial components, including flavonoids, carotenoids, vitamin C dietary fibres. The present study aimed to establish the physiological effects of acute ingestion a purée-based drink (FVPD) on vasodilation, antioxidant status, phytochemical bioavailability other CVD risk factors. A total twenty-four subjects, aged 30–70 years, completed...
Scope Diets low in fruits and vegetables (FV) are responsible for 2.7 million deaths from cardiovascular diseases (CVD) certain cancers annually. Many FV their juices contain flavonoids, some of which increase endothelial nitric oxide synthase (eNOS) activity. A single nucleotide polymorphism the eNOS gene, where thymine (T) replaces guanine (G) at position 894 predicting substitution glutamate aspartate codon 298 (Glu298Asp), has been associated with increased CVD risk due to effects on...
Alginate-coated Lactobacillus acidophilus LA5 or casei 01 was recoated with either 0.1–0.5% (w/v) alginate 0.05–0.15% poly-L-lysine (PLL) plus 0.2% 5–15% gelatin, after which they were determined for survivability in gastric bile longan juices. The morphology of encapsulated probiotic cells illustrated that beads 0.5% showed a more compact surface and greater protective effect than other recoating materials. PLL both strains the highest viability juice. In juice, only best protection beads....