Albin Huang
- Single-cell and spatial transcriptomics
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune cells in cancer
- Hearing, Cochlea, Tinnitus, Genetics
- Cell Image Analysis Techniques
- T-cell and Retrovirus Studies
- 3D Printing in Biomedical Research
- Neural dynamics and brain function
- RNA regulation and disease
- Erythrocyte Function and Pathophysiology
- Virus-based gene therapy research
Stanford University
2017-2022
The Tabula Muris Consortium We have created a compendium of single cell transcriptome data from the model organism Mus musculus comprising more than 100,000 cells 20 organs and tissues. These represent new resource for biology, revealing gene expression in poorly characterized populations allowing direct controlled comparison types shared between tissues, such as T-lymphocytes endothelial distinct anatomical locations. Two technical approaches were used most tissues: one approach,...
Significance Skeletal muscle stem cells (MuSCs) exhibit a high content of heterochromatin. However, little is known about the functional importance heterochromatin maintenance in MuSC homeostasis. Our study uncovered role Hairless (Hr) gene protecting integrity MuSCs. We characterized molecular function Hr and demonstrated its as an antagonist to Histone 3 Lysine 9 demethylases. work has implications for cell during aging.