A5065833346- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- COVID-19 and healthcare impacts
- Liver Disease Diagnosis and Treatment
- Nausea and vomiting management
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Renal function and acid-base balance
- Tracheal and airway disorders
- Pain Management and Opioid Use
- Respiratory Support and Mechanisms
- Cardiac Structural Anomalies and Repair
- Ultrasound in Clinical Applications
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Radiation Dose and Imaging
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Nosocomial Infections in ICU
Post Graduate Institute of Medical Education and Research
2012-2025
Institute of Post Graduate Medical Education and Research
2024
All India Institute of Medical Sciences
2022-2023
Creative Commons
2022-2023
Sharda University
2023
Intensive Care Foundation
2021-2023
MemorialCare Health System
2021
Deutsche Post (Germany)
2021
Asian Institute of Gastroenterology
2021
Institute of Liver and Biliary Sciences
2019
The study aimed to clinically assess the association between periodontitis and COVID-19-related outcomes.Data pertaining patient demographics, medical history, blood parameters, periodontal clinical examination aMMP-8 point-of-care diagnostics (both site-level patient-level) was recorded for eighty-two COVID-19-positive patients. outcomes such as COVID-19 pneumonia, death/survival, types of hospital admission need assisted ventilation were also assessed.Males predominantly afflicted with...
Abstract Background efficacy of therapeutic cholecalciferol supplementation for severe COVID-19 is sparingly studied. Objective effect single high-dose on sequential organ failure assessment (SOFA) score in moderate-to-severe COVID-19. Methods participants with moderate to PaO2/FiO2 ratio < 200 were randomized 0.6 million IU oral (intervention) or placebo. Outcomes primary outcome was change Day 7 SOFA and pre-specified secondary outcomes 28-day all-cause mortality. Results all, 90...
Postoperative pain remains a significant problem in patients undergoing donor nephrectomy despite reduced tissue trauma following laparoscopic living (LLDN). Inadequately treated leads to physiological and psychological consequences, including chronic neuropathic pain. This randomized controlled double-blinded trial was conducted sixty-nine (n = 69) participants who underwent LLDN under general anesthesia. Participants were into Group B 34) C 35). received ultrasound-guided bilateral erector...
Background & Aims: Treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI), with terlipressin and albumin, provides survival benefit, but may be associated cardiopulmonary complications. We analysed the predictors response mortality using point-of-care echocardiography (POC-Echo), cardiac renal biomarkers. Approach: Between December 2021 January 2023, patients HRS-AKI were assessed POC-Echo lung ultrasound within 6h admission, at time starting terlipressin(48h), 72h. Volume expansion...
Background and Aim Echocardiographic assessment of the inferior vena cava diameter (IVCD) collapsibility index (IVCCI) is a noninvasive estimate intravascular volume status (IVS) but requires validation for cirrhosis. We evaluated IVC dynamics in cirrhosis correlated it with conventional tools such as central venous pressure (CVP), pulmonary capillary wedge (PCWP), right atrial (RAP). Methods A total 673 consecutive cirrhotic patients were screened by echocardiography, 125 underwent heart...
Summary Background Point‐of‐care echocardiography (POC‐Echo) is an essential intensive care hemodynamic monitoring tool. Aims To assess POC‐Echo parameters [ i.e ., cardiac index (CI), systemic vascular resistance (SVRI) and cirrhotic cardiomyopathy (CCM) markers] serum biomarkers in predicting circulatory failure (need for vasopressors) mortality patients with acute‐on‐chronic liver (ACLF) having sepsis‐induced hypotension. Methods We performed serial within 6 hours (h) of presentation...
Critically ill patients with cirrhosis and liver failure not uncommonly have hypotension due to multifactorial reasons, that include hyperdynamic state increased cardiac index, low systemic vascular resistance portal hypertension, following the use of beta blocker or diuretic therapy, severe sepsis. These changes are mediated by microvascular alterations in liver, inflammation, activation renin angiotensin aldosterone system, vasodilatation endothelial dysfunction. Hemodynamic assessment...
Patients with cirrhosis are susceptible to decompensation events, including ascites, variceal bleeding (VB), hepatic encephalopathy, or death after COVID-19 infection. may experience post-COVID condition (PCC) multisystem involvement that persists for at least 2 months. Hospitalized patients and between January 2021 2023 were assessed events mortality compared a propensity-matched cohort of non-COVID-19 sepsis. Both groups followed outcomes over 1 year. Of 252 Cirrhosis+ (73% men, aged 48.9...
The severity of COVID-19 infection in transplant patients is much higher when compared to the general population. There are limited data on different organ transplants and their management strategies for infection. This first case series literature review from Asia describing among simultaneous pancreatic kidney (SPK) recipients. a retrospective study 5 who underwent SPK contracted during pandemic. Management was similar treatment employed then because lack conclusive with existing...
Although international guidelines have been developed for emergency tracheal intubation (ETI), there is little evidence of their applicability in developing countries.The aim this study was done to evaluate the different methods ETI that are practiced among anesthetist and anesthesia trainees India outside operating room (OR)/intensive care unit (ICU) settings.This prospective observational audit did personals managing OR ICU.The conducted through an online survey using electronic media....
Intensive care unit (ICU) patients are at an increased risk of many catastrophic events during intrahospital transport (IHT) for various procedures. This study was planned to determine the incidence and types adverse occurring critically ill in a tertiary hospital.This prospective observational conducted ICU hospital 8 months after ethical clearance from institute ethics committee. All transported out audit period diagnostic or therapeutic procedures were included study. Vitals several...
Background Survivors of COVID-19 pneumonia may have residual lung injury and poor physical mental health even after discharge. We hypothesized that severe acute respiratory distress syndrome (ARDS) patients needing mechanical ventilation be at a greater risk deterioration in pulmonary function, health, quality life (QOL). This study analyses the differences QOL recovery, having received non-invasive oxygen therapy versus invasive during ICU stay. Methods Patients aged >18 years, who had...
Postoperative sore throat (POST) is a frequent and undesirable complication after general anesthesia with endotracheal intubation. Various pharmacological non-pharmacological methods variable success rate are used for attenuating POST. However, no single drug has been universally accepted.To compare the effect of betamethasone gel, ketamine gargles intravenous dexamethasone on incidence severity POST.Prospective randomized controlled single-blinded trial conducted at tertiary care centre.A...
Background and objectives Recent randomized controlled trials (RCTs) have indicated potential therapeutic benefits with high-dose dexamethasone (HDD) or tocilizumab (TCZ) plus standard care in moderate to severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS). No study has compared these two against each other. We aimed compare the efficacy safety of HDD TCZ COVID-ARDS. Methods Patients admitted COVID-19 ARDS clinical worsening within 48 hours were randomly...
Acute kidney injury (AKI) is a common complication after on pump coronary artery bypass grafting (CABG) surgery and associated with poor prognosis. Postoperative AKI morbidity, mortality, increase in length of intensive care unit (ICU) stay increases the financial burden. Identifying individuals at risk for developing postoperative period extremely important to optimize outcomes. The aim study evaluate association between intraoperative transesophageal echocardiography (TEE) derived renal...
Abstract Objectives The aim of this study was to validate an active matrix metalloproteinase (MMP‐8) point‐of‐care diagnostic tool in COVID‐19 patients with periodontal disease. Subjects, Materials, and Methods Seventy‐two COVID‐19‐positive 30 COVID‐19‐negative subjects were enrolled the study. Demographic data recorded, examination carried out, chairside tests run for evaluating expression MMP‐8 (aMMP‐8) site maximum breakdown via gingival crevicular fluid sampling as well a mouth...
Patients with cirrhosis and acute-on-chronic liver failure (ACLF) may have bleeding complications need for invasive procedures. Point-of-care (POC) coagulation tests like thromboelastography (TEG) Sonoclot be better guiding patient management than the standard (SCTs), prothrombin time, platelet count international normalized ratio.We prospectively compared validated POC SCTs in 70 persons ACLF 72 decompensated who had clinical checked episodes of re-bleeding transfusion requirements. We...