- Clinical Nutrition and Gastroenterology
- Intestinal Malrotation and Obstruction Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital gastrointestinal and neural anomalies
- Infant Nutrition and Health
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Congenital Anomalies and Fetal Surgery
- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Cardiovascular Disease and Adiposity
- Congenital Diaphragmatic Hernia Studies
- Gastroesophageal reflux and treatments
- Cardiac Imaging and Diagnostics
- Tracheal and airway disorders
- Liver physiology and pathology
- Surgical Simulation and Training
- Organ Transplantation Techniques and Outcomes
- Airway Management and Intubation Techniques
- Liver Disease and Transplantation
- Neonatal Respiratory Health Research
- Gastrointestinal motility and disorders
- Appendicitis Diagnosis and Management
- Pleural and Pulmonary Diseases
- Intraperitoneal and Appendiceal Malignancies
Kagoshima University
2016-2025
Niigata University
2022
Kurume University
2022
Southern Tohoku General Hospital
2011-2021
Kagoshima City Hospital
2017-2019
University of Toronto
2019
Hospital for Sick Children
2019
SickKids Foundation
2019
Ministry of Health Labour and Welfare
2018
University of Alberta
2015-2017
Abstract Background Despite the presence of ganglion cells in rectum, some patients have symptoms similar to those Hirschsprung's disease. A consensus has yet be established regarding terminology for these diseases. We defined this group diseases as “allied disorders disease” and compiled guidelines facilitate accurate clinician diagnosis provide appropriate treatment strategies each Methods These were developed using methodologies Medical Information Network Distribution System ( MINDS )....
Glucagon-like peptide-2 (GLP-2) and epidermal growth factor (EGF) treatment enhance intestinal adaptation. To determine whether these factors exert synergistic effects on function, GLP-2 EGF-containing media (EGF-cm) were administered, alone in combination, neonatal piglet models of short bowel syndrome (SBS). Neonatal Landrace-Large White piglets block randomized to 75% midintestinal [jejunoileal (JI) group] or distal [jejunocolic (JC) resection sham control, with 7-day infusion saline...
To identify the prognostic factors for pediatric severe intestinal motility disorder (IMD).
ABSTRACT Many institutions perform thoracoscopic surgery for pediatric extrapulmonary sequestration (EPS). This approach achieves good cosmetic outcomes due to the small skin incision in comparison open surgery. However, an extension or additional is sometimes necessary extract resected specimens from thoracic cavity, which reduces advantages of this procedure. We herein report 5 cases two‐site (TTS) using extraction wound with left‐sided EPS. In procedure, a camera port was inserted inside...
Combined renal dysfunction worsens the subsequent prognosis in patients after acute myocardial infarction (AMI). Therefore, establishing a therapeutic modality to maintain or improve function AMI is necessary. This study aimed elucidate association between physical activity level and change such patients.Prospective observational study.We enrolled 41 (35 men; average age, 67.5 ± 12.6 years) onset. Blood biochemistry, urinalysis, tests were conducted at discharge 3 months discharge. Renal was...
Background: Parenteral nutrition–associated liver disease (PNALD) continues to cause morbidity and mortality for neonates with intestinal failure. Lipid peroxidation is one potential etiological factor. This study was designed test if supplementing vitamin E into conventional soy‐based lipid would reduce the risk of PNALD. Methods: Sixteen piglets, aged 2–5 days weighing 1.8–2.5 kg, were randomized parenteral nutrition (PN) soy (SO, n = 8) or same plus α‐tocopherol, most bioactive form...
Abstract Introduction Management of neonates with long gap esophageal atresia (LGEA) is one the most challenging situations facing pediatric surgeons. Delayed anastomosis after internal traction for lengthening was reported as a useful technique cases. Additionally, use near‐infrared (NIR) fluorescence imaging indocyanine green (ICG) has gained popularity in surgery, especially blood perfusion validation. We report novel safe and secure LGEA neonatal period using ICG‐guided NIR fluorescence....
Background: We aim to study the efficacy of exogenously administered glucagon‐like peptide 2 (GLP‐2) on intestinal adaptation in preclinical models neonatal short bowel syndrome (SBS) according remnant anatomy, with and without ileum. Furthermore, we determine if this adaptive effect was potentiated enteral nutrition (EN). Methods: Neonatal piglets were block‐randomized 75% mid‐intestinal (JI group, retains ileum) or distal‐intestinal (JC has no resection (sham control) GLP‐2 treatment (11...
Abstract Background Chronic intestinal pseudo‐obstruction ( CIPO ) is a rare disabling and life‐threatening disorder characterized by severe impairment of gastrointestinal peristalsis. While number pharmacotherapeutics have been developed, only few trials carried out for improvement the pathological condition patients. This report describes results nationwide survey on pharmacotherapy used in pediatric Japan. Methods In 2012, was conducted to identify clinical presentation Information...
Objectives The effect of oxidative stress on coronary microvascular disease is unknown. We investigated whether chronic administration ascorbic acid (ASC) or glutathione (GSH) prevents dysfunction and remodeling induced by upstream repeated artery endothelial injury. Methods Balloon injury was at the left anterior descending (LAD), just distal to an implanted flow meter, every 2 weeks for 6 in pigs. Changes LAD blood acetylcholine (ACh) 5-hydroxytryptamine were assessed before each 8 after...