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Pedro Azalim

ORCID: 0000-0003-3272-4321
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About
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A5013934157
Research Areas
  • Ion Transport and Channel Regulation
  • Trypanosoma species research and implications
  • Phytochemistry and Bioactive Compounds
  • ATP Synthase and ATPases Research
  • Phytochemical Studies and Bioactivities
  • Antioxidant Activity and Oxidative Stress
  • Ion channel regulation and function
  • Hormonal Regulation and Hypertension
  • Electrolyte and hormonal disorders
  • Free Radicals and Antioxidants
  • Eicosanoids and Hypertension Pharmacology
  • Drug Transport and Resistance Mechanisms
  • Research on Leishmaniasis Studies
  • Pharmacogenetics and Drug Metabolism
  • Insect Pest Control Strategies

Universidade Federal do Rio de Janeiro
 2018-2025

Fundação Oswaldo Cruz
 2018

 Chemical composition of Ocimum canum Sims. essential oil and the antimicrobial, antiprotozoal and ultrastructural alterations it induces in Leishmania amazonensis promastigotes
OPENALEX - Publications 
Verônica Diniz da Silva Fernando Almeida-Souza Amanda Mara Teles Pedro Azalim Renata Mondêgo‐Oliveira and 5 more Nestor Everton Mendes Filho Noemi Nosomi Taniwaki Ana Lúcia Abreu‐Silva Kátia da Silva Calabrese Victor Elias Mouchrek Filho

10.1016/j.indcrop.2018.04.005 article EN Industrial Crops and Products 2018-04-24
 Pharmacodynamic characterization and evaluation of oxidative stress effects of digitoxigenin derivatives on HeLa cells
OPENALEX - Publications 
Jéssica M. M. Valadares Pedro Azalim Xiaofan Liu Nathallia Cavalcanti Carrozza George A. O’Doherty and 2 more Luis Eduardo M. Quintas Leandro A. Barbosa

10.1007/s00232-024-00334-z article EN The Journal of Membrane Biology 2025-01-15
 Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study
OPENALEX - Publications 
Pedro Azalim Fernando M. do Monte Mariana Manzano Rendeiro Xiaofan Liu George A. O’Doherty and 4 more Carlos Frederico Leite Fontes Suzana Guimarães Leitão Luis Eduardo M. Quintas François Noël

10.1016/j.bcp.2019.113679 article EN Biochemical Pharmacology 2019-10-24
 Revisiting the binding kinetics and inhibitory potency of cardiac glycosides on Na+,K+-ATPase (α1β1): Methodological considerations
OPENALEX - Publications 
François Noël Pedro Azalim Fernando M. do Monte Luis Eduardo M. Quintas Adriana Katz and 1 more Steven J.D. Karlish

10.1016/j.vascn.2018.09.001 article EN Journal of Pharmacological and Toxicological Methods 2018-09-21
 Cytotoxic effect of carbohydrate derivatives of digitoxigenin involves modulation of plasma membrane Ca2+‐ATPase
OPENALEX - Publications 
Jéssica Martins de Moura Valadares Sumit O. Bajaj Hongyan Li Hua‐Yu Leo Wang Simone Cavalcante Silva and 8 more Israel José Pereira Garcia Duane G. Pereira Pedro Azalim Luis Eduardo M. Quintas François Noël Vanessa Faria Cortes George A. O’Doherty Leandro A. Barbosa

Cardiac glycosides, such as digoxin and digitoxin, are compounds that interact with Na

10.1002/jcb.30150 article EN Journal of Cellular Biochemistry 2021-09-22
 Simplified Method for Kinetic and Thermodynamic Screening of Cardiotonic Steroids through the K+-Dependent Phosphatase Activity of Na+/K+-ATPase with Chromogenic pNPP Substrate
OPENALEX - Publications 
Pedro Azalim François Noël Simone Cavalcante Silva José Augusto Ferreira Perez Villar Leandro A. Barbosa and 2 more George A. O’Doherty Luis Eduardo M. Quintas

The antitumor effect of cardiotonic steroids (CTS) has stimulated the search for new methods to evaluate both kinetic and thermodynamic aspects their binding Na

10.1124/molpharm.124.000934 article EN Molecular Pharmacology 2024-08-26
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