A5016123480- Immune Cell Function and Interaction
- IL-33, ST2, and ILC Pathways
- Immunotherapy and Immune Responses
- Eosinophilic Esophagitis
- Hepatitis B Virus Studies
- Probiotics and Fermented Foods
- Antimicrobial Peptides and Activities
- Immune Response and Inflammation
- Physiological and biochemical adaptations
- Ocean Acidification Effects and Responses
- Clostridium difficile and Clostridium perfringens research
- Atherosclerosis and Cardiovascular Diseases
- Metabolism and Genetic Disorders
- Gut microbiota and health
- Animal Virus Infections Studies
- Breastfeeding Practices and Influences
- Diet and metabolism studies
- Cancer, Hypoxia, and Metabolism
- T-cell and B-cell Immunology
- Neonatal and fetal brain pathology
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Respiratory viral infections research
- Mitochondrial Function and Pathology
- Pediatric health and respiratory diseases
University of Palermo
2024
University of Genoa
2019-2023
University of Messina
2015
In Sicily (Italy), respiratory syncytial virus (RSV), rhinovirus (HRV), and influenza triggered epidemics among children, resulting in an increase acute tract infections (ARTIs). Our objective was to capture the epidemiology of determining which pathogens were associated with following lockdown whether there changes epidemiological landscape during post-SARS-CoV-2 pandemic era. Materials Methods: We analyzed multiplex viral PCR data (BioFire® FilmArray® Respiratory Panel 2.1 Plus) from 204...
Background and Aims Natural killer (NK) cells play a crucial role in the clearance of human viruses but their activity is significantly impaired patients infected with chronic hepatitis B (CHB). Cooperation dendritic (DCs) pivotal for obtaining optimal NK cell antiviral function; thus, we investigated whether HBV might impact ability DCs to sustain functions. Approach Results Human were poor stimulators interferon‐gamma (IFN‐γ) production by when exposed HBV, while maintaining capability...
Abstract Polyvalent mechanical bacterial lysate is effective in the prevention of respiratory tract infections, although its mechanism action not entirely elucidated. Because epithelial cells constitute frontline defense against we investigated molecular mechanisms innate response exerted by bronchial presence polyvalent lysate. By using primary human cells, observed that was able to increase expression cellular adhesion molecules such as ICAM-1 and E-cadherin, well amphiregulin, a growth...
Abstract Natural killer (NK) cells represent innate effector potentially able to play a role during the immune response against multiple myeloma (MM). To better define distribution and specific properties of NK cell subsets MM disease, we analyzed their features in bone marrow peripheral blood newly diagnosed patients. Our findings revealed that, both compartments, were more abundant than healthy donors. Among total MM-NK cells, significant increase CD94lowCD56dim subset was observed, which...
Human CD117+ CRTH2neg innate lymphoid cells (ILC) comprise multipotent precursors (ILCp), which are able to differentiate into subtypes in response different signals received peripheral tissues. NKp46+ ILCp have been reported associate with ILC3 whereas KLRG1+ ILC2, although the latter can also generate other ILC subsets, thus, maintaining a substantial plasticity. We here showed that CD62L is expressed by exclusively within population and its expression marks loss of their broad...