A5043479814- Celiac Disease Research and Management
- Pediatric Urology and Nephrology Studies
- Urinary Tract Infections Management
- Liver Diseases and Immunity
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Digestive system and related health
- Vitamin D Research Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Hemoglobinopathies and Related Disorders
- Eosinophilic Esophagitis
- Hepatitis Viruses Studies and Epidemiology
- Tracheal and airway disorders
- Urinary Bladder and Prostate Research
- Parathyroid Disorders and Treatments
- Healthcare cost, quality, practices
- Esophageal and GI Pathology
- Pneumonia and Respiratory Infections
- Ion Transport and Channel Regulation
- Mitochondrial Function and Pathology
- Liver Disease and Transplantation
- Lipid metabolism and disorders
- Inflammatory Myopathies and Dermatomyositis
- Renal Diseases and Glomerulopathies
- Microbial Metabolites in Food Biotechnology
University of Ferrara
2016-2025
Ospedale San Bassiano
2023
Arcispedale Sant'Anna
2010-2018
RELX Group (United States)
2017
Ospedale Sant'Anna
2013
Background Oral deferiprone was suggested to be more effective than subcutaneous desferrioxamine for removing heart iron. once-daily chelator deferasirox has recently been made commercially available but its long-term efficacy on cardiac iron and function not yet established. Our study aimed compare the effectiveness of deferasirox, myocardial liver concentrations bi-ventricular in thalassemia major patients by means quantitative magnetic resonance imaging.Design Methods From first 550...
Urinary tract infection (UTI) is one of the most common infectious diseases in pediatric population and represents a major cause antibiotic consumption hospitalization children. Considering ongoing controversies on management UTI challenges due to increasing antimicrobial resistance, aim present study was evaluate level agreement age Emilia-Romagna Region, Italy, assess basis recent studies whether there need change current recommendations used by primary care pediatricians, hospital...
Financial toxicity (FT) refers to the negative impact of health-care costs on clinical conditions. In general, social determinants health, especially poverty, socioenvironmental stressors, and psychological factors, are increasingly recognized as important non-communicable diseases, such chronic kidney disease (CKD), their consequences. We aim investigate prevalence FT in patients at different stages CKD treated our universal system from pediatric nephrology, hemodialysis, peritoneal...
Human respiratory syncytial virus (hRSV) is ubiquitous and causes diseases in both children adults. Worldwide, hRSV pneumonia the second cause of postnatal infant death after malaria. Given high impact terms morbidity, mortality costs, especially pediatric population, recognized as a global health problem WHO, view availability new vaccines, has urged an active surveillance program virus-related infections. The aim this study been to evaluate infections Italian particularly one,...
The development and spread of antibiotic resistance is an increasingly important global public health problem, even in paediatric urinary tract infection (UTI). In light the variability data, it necessary to conduct surveillance studies determine prevalence specific geographical areas optimize therapeutic management. this observational, retrospective, multicentre study, medical records 1801 patients who were hospitalised for UTI between 1 January 2012, 30 June 2020, Emilia-Romagna, Italy,...
In Sicily (Italy), respiratory syncytial virus (RSV), rhinovirus (HRV), and influenza triggered epidemics among children, resulting in an increase acute tract infections (ARTIs). Our objective was to capture the epidemiology of determining which pathogens were associated with following lockdown whether there changes epidemiological landscape during post-SARS-CoV-2 pandemic era. Materials Methods: We analyzed multiplex viral PCR data (BioFire® FilmArray® Respiratory Panel 2.1 Plus) from 204...
Wilms tumor-suppressor gene-1 (WT1) plays a key role in kidney development and function. WT1 mutations usually occur exons 8 9 are associated with Denys-Drash, or intron Frasier syndrome. However, overlapping clinical molecular features have been reported. Few familial cases described, intrafamilial variability. Sporadic of isolated diffuse mesangial sclerosis focal segmental glomerulosclerosis also reported.Molecular analysis was carried out five members on three generations family...
Objective The prevalence of coeliac disease (CD) in Vietnam is unknown. To fill this void, we assessed the serological markers CD autoimmunity a population children Hanoi. Setting outpatient blood drawing laboratory largest paediatric hospital North was used for study, which part an international project collaboration between Italy and Vietnam. Participants Children having drawn any reason were included. Exclusion criteria age younger than 2 years, acquired or congenital immune deficiency...
Adult-type hypolactasia (ATH) is a clinical syndrome of primary lactase deficiency. A lactose-free diet advisable to avoid the symptoms linked condition, but this potentially creates problems for optimal bone mineralization due reduced calcium intake. To evaluate effect on mineral status (BMS), we compared phalangeal BMS adolescents with ATH that peers normal diet. Also, analyzed correlations between and dietary behavior, physical exercise, vitamin D total 102 cases healthy controls filled...
Abstract Glycerol‐3‐phosphate dehydrogenase 1 deficiency is a rare autosomal recessive disorder caused by mutations in the GPD1 gene (GPD1; OMIM*138420). Very few cases are reported literature. It usually manifests early infancy with transient hypertriglyceridemia, hepatomegaly, steatosis, and fibrosis. We report case of 16‐year‐old boy followed since age year for elevated liver enzymes, persistent hypertriglyceridemia. Abdominal ultrasound showed diffuse echogenicity biopsy disclosed...
With the spread of antibiotic resistance in pediatric urinary tract infections (UTIs), more patients are likely to be started empirically on antibiotics which pathogens later found resistant (discordant therapy). However, in-vivo effectiveness may different from in-vitro susceptibility. Aims this study were describe clinical outcomes discordant empirical treatments UTIs and investigate risk factors associated treatment failure. This observational, retrospective was conducted children...
Aim: of the study was to analyse impact SXR rs3842689 polymorphism on response corticosteroids in pediatric idiopathic nephrotic syndrome. Patients & methods: 66 children (56 steroid-sensitive, ten steroid-resistant) were studied for gene distribution. Results: Steroid sensitive patients accounted 96% cases with In/In polymorphism, but only 53% Del/Del At odds ratio analysis, represented a clear risk factor steroid resistance (OR: 20.57; p = 0.009), while favourable prognostic sensitivity....
Background Preschool age (i.e. children under six years of age) represents a red flag for requiring neuroimaging to exclude secondary potentially urgent intracranial conditions (PUIC) in patients with acute headache. We investigated the clinical characteristics preschoolers headache identify features associated greater risk “dangerous” Methods performed multicenter exploratory retrospective study Italy from January 2017 December 2018. Preschoolers new-onset non-traumatic admitted emergency...