A5049286038- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Ion Transport and Channel Regulation
- Renal Diseases and Glomerulopathies
- Urinary Tract Infections Management
- Renal and Vascular Pathologies
- Kidney Stones and Urolithiasis Treatments
- Renal and related cancers
- Parathyroid Disorders and Treatments
- Renal function and acid-base balance
- Autoimmune Bullous Skin Diseases
- Urological Disorders and Treatments
- Vasculitis and related conditions
- Magnesium in Health and Disease
- Erythropoietin and Anemia Treatment
- Muscle and Compartmental Disorders
- Connective tissue disorders research
- Neuroendocrine Tumor Research Advances
- Urticaria and Related Conditions
- Electrolyte and hormonal disorders
- Oral and gingival health research
- Dermatological and Skeletal Disorders
- Vascular anomalies and interventions
- Hemoglobinopathies and Related Disorders
- Neurological Complications and Syndromes
Marmara University
2015-2025
Ümraniye Eğitim ve Araştırma Hastanesi
2018-2023
Sağlık Bilimleri Üniversitesi
2023
Pediatrics and Genetics
2022-2023
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2012
Boğaziçi University
2006
Istanbul University
2006
Amerikan Hastanesi
2006
ABSTRACT Background Two earthquakes on 6 February 2023 destroyed 10 cities in Türkiye. We report our experience with pediatric victims during these catastrophes, a focus crush syndrome related–acute kidney injury (Crush-AKI) and death. Method Web-based software was prepared. Patient demographics, time under rubble (TUR), admission laboratory data, dialysis, overall outcomes were recorded. Results A total of 903 injured children (median age 11.62 years) evaluated. Mean TUR 13 h (interquartile...
<title>Abstract</title> A 3-year-old boy presented with dark-colored urine for four months. His history was negative infections, but he taking oral methylcobalamin treatment a persistent deficiency. parents were first-degree cousins, and female cousin had proteinuria of unknown etiology. physical examination laboratory revealed no abnormalities except nephritic low levels vitamin B12. Albumin the main protein in urine. Kidney biopsy showed nonspecific changes. Genetic analysis identified...
The causative agent spectrum and resistance patterns of urinary tract infections in children are affected by many factors.To demonstrate antibiotic changing ratio years.Retrospective cross-sectional study.We analysed isolated Gram (-) bacteria during the years 2011-2014 (study period 2) with infections. We compared these findings data collected same centre 2001-2003 1).Four hundred sixty-five uncomplicated community-acquired were from 400 2011-2014. Sixty-one percent patients female (1.5...
The authors studied 20 patients with subacute sclerosing panencephalitis (SSPE) to investigate the correlations between MRI, magnetic resonance spectroscopy (MRS), and clinical status. MRI findings did not correlate By contrast, all had reductions in <i>N</i>-acetyl aspartate (NAA) increase myoinositol (mI) (<i>p</i> < 0.01), NAA mI concentrations correlated severity 0.05). During follow-up, continued decline. <sup>1</sup>H-MRS may be a useful measure of disease progression SSPE.
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are defined as structural malformations and/or tract. Heat shock proteins (HSPs) expressed in response to cellular changes, such thermal, hemodynamic, osmotic, inflammatory, mechanical stresses. This study aimed assess uHSP70 levels during acute infections (UTI) non-infection periods patients with CAKUT, evaluate whether is elevated CAKUT subtypes. Methods Among 89 UTI (CAKUT-A), 111 without (CAKUT-B), 74 healthy...
The incidence of anemia increases with the stage chronic kidney disease (CKD). Erythropoietin (EPO) deficiency is a common cause in CKD. Erythropoietin-stimulating agents (ESAs) are mainstay treatment. Treatment can be challenging due to erythropoietin resistance (ER), which assessed using index (ERI). Our aim was investigate factors contributing high ERI levels children receiving renal replacement therapy (RRT). Thirty-three RRT for at least 3 months were included. mean value 15.7...
Background/aim: We analyzed the clinical and pathological features prognosis of 106 children with persistent asymptomatic microscopic hematuria (PAMH) or without mild proteinuria. Materials methods: This was a retrospective study who were referred to our clinics from 2000 2013 for evaluation PAMH. Results: Among patients, 69 (65%) female 37 (35%) male. The patients divided into two groups: 101 isolated (IMH) 5 proteinuria (AMHP). Renal biopsy performed in all AHMP: 2 had hereditary...
Generalized arterial calcification of infancy (GACI) is a rare autosomal-recessive disorder, characterized by the internal elastic lamina, fibrotic myointimal proliferation muscular arteries and resultant stenosis.Treatment with bisphosphonates has been proposed as means reducing calcifications in GACI patients, although there no formalized treatment approach.The case reported here was patient severe diagnosed at three months age who had response to bisphosphonate treatment, but clinically...
Bartter syndrome (BS) is a group of autosomal-recessive tubular disorders and it classified into five genetic subtypes. BS can also be by phenotype (antenatal, classic). Patients with mutations in the same gene present different phenotypes. In study, target sequencing was performed to evaluate genotype-phenotype relationship.Biochemical, clinical renal ultrasonography results were collected at presentation last clinic visit. Genetic analyses performed. The findings patients classical (cBS)...
What is already known on this topic?Nephrogenic diabetes insipidus (NDI) caused by the resistance of antidiuretic hormone principal cells renal collecting ducts in which water absorption hampered.NDI a rare cause hypernatremic dehydration neonatal period.What does study add?Early partial but transient response to ADH possible NDI.
Antiphospholipid syndrome (APS), particularly the catastrophic antiphospholipid (CAPS), is one of rare causes thrombotic microangiopathy (TMA). CAPS most severe form APS, especially when accompanied by complement dysregulation, progressive microvascular thrombosis and failure in multiple organs. In this report, a case with TMA genetic defect system presented.A 13-year-old girl was admitted to hospital oliguric acute kidney injury, nephrotic range proteinuria, Coombs positive hemolysis,...
We aimed to evaluate the clinical parameters, histopathological findings of nephrotic syndrome (NS) patients, and independent factors predicting steroid resistance in a single tertiary center. One hundred sixty-two children (57 girls 105 boys) with NS who were followed between 1998 2018 analyzed this retrospective cohort. The median (interquartile range; range) age follow-up time 4.9 (5.7; 0.1-16.8) 5.5 (5.4; 0.1-20.3) years. A total 82.7% patients steroid-sensitive (SSNS) 17.3%...
Objective: The most common form of nephrotic syndrome (NS) is minimal change disease (MCD) in children and focal segmental glomerulosclerosis (FSGS) following it. As, it important to predict corticosteroid (CS) response at the beginning disease, we aimed evaluate efficacy some biomarkers terms predicting steroid patients with NS. Patients Methods: Twenty who met inclusion criteria for study were divided into 3 groups 6 healthy control participants included analysis as 4th group. Group-1 10...
Abstract Background Hereditary hypophosphatemia (HH), is a rare condition related to decreased renal tubular phosphate reabsorption. Although X-linked or PHEX gene variant the most frequent cause of HH, recent advances in next-generation sequencing (NGS) techniques enable identification genetic etiologies as whole. Objective To identify causes HH using various testing methods and compare clinical features between FGF23-dependent FGF23-independent groups. Design Methods Fifty patients (24...
Moyamoya hastalığı, iki taraflı terminal internal karotis arter ile orta ve ön serebral arterin kronik ilerleyici darlığıdır. Oluşan kollaterallerin anjiyografik görüntüsüne, Japonca 'havada dağılan duman' anlamına gelen 'moyamoya' ismi verilmiştir. hastalığı renovasküler hipertansiyon birlikteliği nadirdir. Bu çalışmada, moyamoya bulunan erkek olgu sunulmuştur. Dokuz yaşındaki olgu, bilinç bulanıklığı anlamsız konuşma şikâyetleri hastanemize başvurdu. Fizik muayenesinde sağ hemiparezi...
We aimed to present the characteristics, genetic analysis results, long-term progno- sis of our patients with distal kidney tubular acidosis, and relationship between hyperam- monemia acidosis.Biochemical, clinical, imaging findings were collected at presen- tation last clinic visit, results recorded.Our study included 9 (3 female, 33%). The median age diagnosis was 3 months, follow-up period 111 months. Height standard deviation scores less than -2 in 4 (44%) presentation (33%) visit....