A5084050894- Bone health and treatments
- Bone and Joint Diseases
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
- Oral and Maxillofacial Pathology
- Cancer, Hypoxia, and Metabolism
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Oral Health Pathology and Treatment
- Laser Applications in Dentistry and Medicine
- Periodontal Regeneration and Treatments
- Head and Neck Cancer Studies
- Mesenchymal stem cell research
- Radiopharmaceutical Chemistry and Applications
- Orthopaedic implants and arthroplasty
- Osteomyelitis and Bone Disorders Research
- Dental Radiography and Imaging
- Bone Metabolism and Diseases
- Oral and gingival health research
- Salivary Gland Tumors Diagnosis and Treatment
- Bone and Dental Protein Studies
- Anesthesia and Sedative Agents
- Dental materials and restorations
- dental development and anomalies
Philipps University of Marburg
2016-2023
Universitätsklinikum Gießen und Marburg
2016-2023
Johannes Gutenberg University Mainz
2009-2022
DRK Krankenhaus Alzey
2022
University Medical Center of the Johannes Gutenberg University Mainz
2010-2016
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2011-2014
National Medical Research Center of Dentistry and Maxillofacial Surgery
2010
German Cancer Research Center
2008
Georg Speyer Haus
2008
Heidelberg University
2008
Bone marrow mononuclear cells (BMC) from patients with ischemic cardiomyopathy (ICMP) show a reduced neovascularization capacity in vivo . NO plays an important role neovascularization, and bioavailability is typically ICMP. We investigated whether the impaired of ICMP patient-derived progenitor can be restored by pretreatment novel endothelial synthase (eNOS) transcription enhancer AVE9488 (AVE). Ex BMC AVE significantly increased eNOS mRNA expression 2.1-fold ( P < 0.05) activity as...
Titanium (Ti) surface roughness and hydrophilicity are key factors to regulate osteogenic cell responses during dental implant healing. In detail, specific integrin-mediated interactions with the extracellular environment trigger relevant like differentiation matrix synthesis via transcriptions factors. Aim of this study was monitor surface-dependent adhesion dynamics, proliferation, over a period 7 days.Ti disks were manufactured present smooth pretreatment (PT) surfaces rough...
Oral Diseases (2011) 17 , 194–199 Objectives: Bisphosphonate‐associated osteonecrosis of the jaw (BP‐ONJ) is a side effect in patients being treated with bisphosphonates. The bisphosphonates most often associated BP‐ONJ are highly potent nitrogen‐containing bisphosphonates, e.g. pamidronate or zoledronate. In terms aetiology, several theories discussed: inhibition bone remodelling, on soft tissues, and antiangiogenic aim this vitro study was to investigate different osteoblasts, fibroblasts...
Circulating blood-derived vasculogenic cells improve neovascularization of ischemic tissue by a broad repertoire potential therapeutic actions. Whereas initial studies documented that the incorporate and differentiate to cardiovascular cells, other suggested short-time paracrine mechanisms mediate beneficial effects. The question remains what extent physical incorporation is contributing effects cell therapy. By using inducible suicide gene thymidine kinase deplete transplanted we determined...
In the present study, we investigated whether proangiogenic growth factors and endothelial progenitor cells (EPCs) induce favourable effects on cutaneous incisional wound healing in diabetic mice. The of human EPCs were initially analyzed using a HUVEC vitro angiogenesis assay an vivo Matrigel nude mice (n=12). For model, 48 Balb/c with streptozotocin (STZ)-induced diabetes divided randomly into 4 groups (12 each group). Subsequently, 3, 5 7 days before 15‑mm full-thickness skin was set,...
Objectives: Non-Hodgkin lymphomas are malignant neoplastic proliferations of the immune system that can manifest as nodal or extranodal lymphomas.The aim this study was to retrospectively investigate site occurrence in head and neck area analyze typical symptoms patients who presented at an oral maxillofacial surgical department.Material Methods: All patient files from1971 until 2012 from Oral Maxillofacial Surgery a University were analyzed for diagnosis non-Hodgkin lymphoma.Epidemiologic...