A5040555630- Veterinary Oncology Research
- Dermatology and Skin Diseases
- Nail Diseases and Treatments
- Veterinary Equine Medical Research
- Hair Growth and Disorders
- Veterinary Orthopedics and Neurology
- Skin and Cellular Biology Research
- Dermatological diseases and infestations
- Vector-Borne Animal Diseases
- Immune Response and Inflammation
- Human-Animal Interaction Studies
- Veterinary Practice and Education Studies
- Infectious Diseases and Mycology
- Rabies epidemiology and control
- Antimicrobial Peptides and Activities
- Genetic and rare skin diseases.
- Food Allergy and Anaphylaxis Research
- Adrenal Hormones and Disorders
- Gut microbiota and health
- Veterinary Medicine and Surgery
- Asthma and respiratory diseases
- Clostridium difficile and Clostridium perfringens research
- Veterinary Pharmacology and Anesthesia
- Ear Surgery and Otitis Media
- Hidradenitis Suppurativa and Treatments
University of London
2013-2024
Royal Veterinary College
2014-2024
Hertfordshire Community NHS Trust
2019
Medizinische Hochschule Hannover
1998-2000
The domestic dog may be the most morphologically diverse terrestrial mammalian species known to man; pedigree dogs are artificially selected for extreme aesthetics dictated by formal Breed Standards, and breed-related disorders linked conformation ubiquitous diverse. Brachycephaly–foreshortening of facial skeleton–is a discrete mutation that has been in many popular breeds e.g. Bulldog, Pug, French Bulldog. A chronic, debilitating respiratory syndrome, whereby soft tissue blocks airways,...
Abstract Selection for brachycephalic (foreshortened muzzle) phenotypes in dogs is a major risk factor obstructive airway syndrome (BOAS). Clinical signs include respiratory distress, exercise intolerance, upper noise and collapse. Efforts to combat BOAS may be constrained by perception that it ‘normal’ dogs. This study aimed quantify owner-perception of the clinical as veterinary problem. A questionnaire-based was carried out over five months on owners referred Queen Mother Hospital Animals...
Concern has arisen in recent years that selection for extreme facial morphology the domestic dog may be leading to an increased frequency of eye disorders. Corneal ulcers are a common and painful problem dogs can lead scarring and/or perforation cornea, potentially causing blindness. Exaggerated juvenile-like craniofacial conformations wide eyes have been suspected as risk factors corneal ulceration. This study aimed quantify relationship between ulceration conformational including relative...
Concern has been raised regarding the potential contributions of veterinary antimicrobial use to increasing levels resistance in bacteria critically important human health. Canine pyoderma is a frequent, often recurrent diagnosis pet dogs, usually attributable secondary bacterial infection skin. Lesions can range severity based on location, total area and depth tissue affected therapy recommended for resolution. This study aimed describe patient signalment, disease characteristics treatment...
Intervertebral disc extrusion (IVDE) is a common neurological disorder in certain dog breeds, resulting spinal cord compression and injury that can cause pain deficits. Most extrusions are reported chondrodystrophic breeds (e.g. Dachshunds, Basset Hounds, Pekingese), where selection for 'long low' morphologies linked with intervertebral discs abnormalities predispose dogs to IVDE. The aim of this study was quantify the relationship between relative thoracolumbar vertebral column length IVDE...
Abstract Skin fold dermatitis (intertrigo) is an inflammatory process of closely apposing skin surfaces. Extreme conformations towards folded in many dog breeds are linked with higher risk. Using anonymised primary-care veterinary data from the VetCompass Programme, this study aimed to report frequency, demographic risk factors and clinical management for UK. Risk factor analysis used random effects multivariable logistic regression modelling. From a population 905,553 dogs, one-year period...
Objectives To explore epidemiological features of demodicosis relevant to UK veterinary general practitioners. Breed risk factors were proposed as distinct between juvenile‐onset and adult‐onset disease. Materials Methods The study used anonymised clinical data on dogs under primary care at practices enrolled in the VetCompass Programme. Case inclusion required recording a final diagnosis for dermatological condition that was present during 2013 period. Risk factor analysis multivariable...
Background Despite conflicting data on their utility and no reports interlaboratory reproducibility, serum food‐specific antibodies are commonly assayed in first‐opinion canine practice. Hypothesis/Objectives To determine both the variability of test results between two laboratories frequencies magnitudes food reactivity dogs different disease status. Animals Sera were obtained from eight with cutaneous adverse reaction (Group A ), 22 nonfood‐induced atopic dermatitis B 30 an...
O bjectives : To describe systemic glucocorticoid usage in cats and dogs by three primary care ‐veterinary practices England to ascertain risk factors for clinical use. evaluate consistency of prescribing patterns across clinics. validate a merged database veterinary data as functional tool epidemiological research. M ethods A was established from on 31,273 cat dog consultations with pharmacotherapy England. Descriptive statistics described drug use while mixed‐effects logistic regression...
Crosslinking of immunoglobulin E antibodies (IgE) bound at the surface mast cells and subsequent mediator release is considered most important trigger for allergic reactions. Therefore, genetic control IgE levels studied in context diseases, such as asthma, atopic rhinitis, or dermatitis (AD). We performed genome-wide association studies 161 Labrador Retrievers with regard to total allergen-specific levels. identified a significant on CFA 5 antigen-specific responsiveness Acarus siro....
The West Highland White Terrier (WHWT) is a relatively common breed in the UK, although Kennel Club registrations have declined recent years. VetCompass™ Programme collates de-identified clinical data from primary-care veterinary practices UK for epidemiological research. Using VetCompass data, this study aimed to characterise demography, longevity and disorders of WHWTs under primary care UK.WHWTs comprised 6605/905,544 (0.7%) dogs during 2016 886 clinics. Mean adult bodyweight was 9.6 kg...
Veterinarians have recognised a nonpruritic skin disease in the Golden retriever breed characterised by excessive scaling of large, variably pigmented flakes otherwise healthy dogs. This prospective case series describes clinical, histopathological, ultrastructural and genetic features this cornification defect 17 affected The condition affects young dogs either sex is symmetrical, predominantly ventro-lateral hyperpigmentation trunk. Histopathological changes stratum corneum are suggestive...
Non-neoplastic anal sac disorders (ASD) are frequent presentations for dogs in primary-care practice but evidence-based information on disease occurrence and risk is sparse. This study estimates prevalence, breed associations other factors as well reporting clinical management.A cohort of attending VetCompass practices between 1 January 2013 31 December 2013. Risk factor analysis used multivariable logistic regression methods.Of 104,212 110 UK practices, the 1-year period prevalence ASD was...
Otitis externa (OE) is a common disorder in dogs. Infection by the commensal yeast, Malassezia pachydermatis, may result chronic disease that does not respond to standard primary care. Chronic infectious OE be associated with otitis media (OM).To report medical management, clinical outcomes and frequency of middle ear involvement, dogs unresponsive care.Fifty-nine from one referral veterinary hospital January 2007 September 2018.Retrospective analysis records referred treated for at...
DOGS, cats and small mammals are extremely popular companions ‐ they usually share their owners’ home environment physical contact with these pets is often very close. While zoonoses represent an important type of pet‐associated health hazard, a large proportion the pet‐owning public unaware potential for transmission disease between animals humans. In view increasing population immunocompromised people animals, medical veterinary professionals need to be well informed about zoonoses. This...
Objectives To gain information on hair loss amongst curly coated retrievers by questionnaire and to define the clinical pathological features of coat abnormalities in affected dogs United Kingdom Sweden. Materials Methods Questionnaires were completed members Curly Coated Retriever Clubs. Fourteen (six Kingdom, eight Sweden) clinically examined skin/hair samples collected for microscopy histopathology. Blood was haematological, biochemical endocrine assays. Results Of 90 surveyed, 39 had...