A5001173705- Bone health and osteoporosis research
- Nutrition and Health in Aging
- Frailty in Older Adults
- Hip and Femur Fractures
- Body Composition Measurement Techniques
- Vitamin D Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Bone health and treatments
- Elasticity and Material Modeling
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Bone fractures and treatments
- Medical Imaging and Analysis
- Aging and Gerontology Research
- Chronic Disease Management Strategies
- Global Health Care Issues
- Healthcare Policy and Management
- Health disparities and outcomes
- Parkinson's Disease Mechanisms and Treatments
- Balance, Gait, and Falls Prevention
- Bone Metabolism and Diseases
- Health and Well-being Studies
- Psychological Well-being and Life Satisfaction
- Eating Disorders and Behaviors
- Neurological disorders and treatments
Vilnius University
2016-2025
Advisory Board Company (United States)
2021
CHR Verviers
2021
University of Latvia
2019
State Research Institute Centre for Innovative Medicine
2012-2013
Objectives The Sarcopenia Quality of Life (SarQoL) questionnaire, a sarcopenia-specific patient-reported outcome measure, evaluates quality life with 55 items. It produces 7 domain scores and 1 overall score, all between 0 100 points. This study aims to contribute the interpretation SarQoL by calculating standard error measurement (SEM) smallest detectable change (SDC) in sample subjects from 9 studies. Methods Subjects studies (conducted Belgium, Brazil, Czech Republic, England, Greece,...
BACKGROUND AND OBJECTIVE. Variation of osteoporosis in the population is result an interaction between genotype and environment, genetic causes are being widely investigated. The aim this study was to analyze association polymorphisms vitamin D receptor (VDR), type I collagen (COL1A1), lactase (LCT) genes severe postmenopausal as well bone mineral density (BMD). MATERIAL METHODS. A total 54 women with 77 controls (mean age, 58.3 years [SD, 6.2] 56.7 7.42], respectively) were included into...
Although the falls in elderly people lead to serious health consequences, economic burden is underestimated. The aim of this study was calculate medical costs fall consequences women. Women aged 65 years and older were interviewed by phone recording healthcare procedures related every sustained during previous 12 months. estimated calculating sum for all self-reported contacts with care providers: ambulance, emergency department, visits family doctor other specialists, hospitalisations,...
Vitamin D receptor (VDR) is one of the main mediators vitamin biological activity. VDR dysfunction might substantially contribute to development postmenopausal osteoporosis (PMO). Numerous studies have revealed effects several gene variants on risk, although significant variation in different ethnicities has been suggested. The purpose this work was assess frequency distribution genetic with established effect and evaluate their haplotype association risk PMO a cohort Belarusian Lithuanian...
Long-term treatment is used in patients with osteoporosis, and bisphosphonates (BPs) are the most commonly prescribed medications. However, some this therapy not effective, cause different side effects complications. Unfortunately, at least one year needed to identify confirm an ineffectiveness of BPs on bone mineral density (BMD). Among other factors, a response may also be explained by genetic factors. The aim study was analyze influence SOST, PTH, FGF2, FDPS, GGPS1, LRP5 gene variants...
Background and Objectives: Information on how psychomotor speed is associated with the risk of falling scarce, even in older adults. Therefore, this study aimed to determine relationship between falls adults sarcopenia frailty. Materials Methods: A total 204 subjects (aged 83 (77–87) years) participated study: 161 women (78.9%) 43 men (21.1%). The history was assessed by asking whether subject had experienced a fall past 12 months. Psychomotor evaluated reaction time frequency movement....
Frailty is a common syndrome in the elderly, marked by an increased risk of negative health outcomes such as falls, disability and death. It important to detect frailty early accurately apply timely interventions that can improve results older adults. Traditional evaluation methods often depend on subjective evaluations clinical opinions, which might lack consistency. This research uses deep learning classify from spectrograms based IMU data collected during gait analysis. The study...
Background and objectives: One of the greatest challenges facing healthcare aging population is frailty. There growing scientific evidence that gait assessment using wearable sensors could be used for prefrailty frailty screening. The purpose this study was to examine ability a sensor-based discriminate between levels (robust, prefrail, frail). Materials methods: 133 participants (≥60 years) were recruited assessed Fried criteria. Gait wireless inertial attached by straps on thighs, shins,...
Introduction The influence of physical frailty and sarcopenia (PFS) on the well-being older people continuous pressure healthcare systems has prompted a research pathophysiology molecular mechanisms these conditions. Nonetheless some biomarkers have been suggested as potential markers for PFS none them shown to highlight complex nature PFS, which reveals that there is need an understanding possible biomarker candidates. aim this study was identify current hotspots, status, trends in field...
Few epidemiological data on hip fractures were previously available in Lithuania. The aim of this study was to estimate the incidence and hospital costs Vilnius 2010. Data collected from medical charts all patients admitted hospitals (population, 548,835) due new low-energy trauma fracture, during estimated included ambulance transportation continuous hospitalisation immediately after a which are covered by Lithuanian healthcare system. 252 (308 women 160 men) per 100,000 inhabitants aged...
This paper presents a finite element method (FEM)-based fracture risk assessment in patient-specific osteoporotic lumbar vertebra L1. The influence of osteoporosis is defined by variation parameters such as thickness the cortical shell, bone volume–total volume ratio (BV/TV), and trabecular score (TBS). mechanical behaviour using Ramberg–Osgood material model. study involves static nonlinear dynamic calculations von Mises stresses follows statistical processing obtained results order to...
Despite the growing number of octogenarians, little is known about their vitamin D status and activities daily living (ADL) relations.The aim this study was to investigate peculiarities ADL assess relations in octogenarians.A cross-sectional performed at National Osteoporosis Centre located Vilnius, Lithuania. Community-dwelling ambulatory persons aged ≥80 years were included. Current users supplements excluded. Total 25 hydroxyvitamin concentration serum measured with Cobas E411. Functional...
Background and Objectives: It is thought that muscle bone interact only on a biomechanical level, however, some research now emerging links cellular level. The aim of this study was to explore associations between physical function, mass density in community-dwelling elderly men with sarcopenia. A secondary goal analyze if morphology associated functioning. Materials Methods: Body composition measured by dual-energy X-ray absorptiometry (DXA). Bone evaluated according WHO criteria....
Introduction: Ageing is associated with several physical, psychological, and behavioral changes. These changes are closely related general health problems quality of life in old age. The CASP-19 multidimensional instrument was specially designed to measure the elderly. different language versions this scale have been used more than 20 countries. However, Lithuanian translation not available. objective our study test psychometric properties version questionnaire. Materials methods: A...
Abstract Osteoporosis causes the bone mass loss and increased fracture risk. This paper presents modelling of osteoporotic human lumbar vertebrae L1 by employing finite elements method (FEM). The isolated inhomogeneous vertebral body is composed cortical out-er shell cancellous bone. level contribution characterised reducing thickness elasticity modulus using power-law dependence with apparent density. strength parameters are evaluated on basis von Mises-Hencky yield criterion. Parametric...
Abstract Background: One of the greatest challenges facing healthcare aging population is frailty. There growing scientific evidence that gait assessment using wearable sensors could be used for prefrailty and frailty screening. The purpose this study was to examine ability a sensor-based discriminate between levels (robust, prefrail, frail).Methods: 133 participants (≥ 60 years) were recruited assessed Fried criteria. Gait wireless inertial attached by straps on thighs, shins, feet....
Abstract In a hospital-based study we investigated the prevalence of Parkinson’s disease among inhabitants Vilnius city, capital Lithuania. The group was selected from patients who were diagnosed with during time frame 1978-2005. Patients’ diagnosis based on data dispensary cards, registration journals and/or other documentation. A questionnaire and Mini Mental State Examination provided for analysis conditions patients. in is 1.32/1000 higher men than women (p < 0.05). age onset same...