A5101440456- Gut microbiota and health
- Head and Neck Anomalies
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Thyroid and Parathyroid Surgery
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Pelvic and Acetabular Injuries
- Musculoskeletal pain and rehabilitation
- Sinusitis and nasal conditions
- Mycobacterium research and diagnosis
- Bone fractures and treatments
- Industrial Vision Systems and Defect Detection
- Clostridium difficile and Clostridium perfringens research
- Genetic Syndromes and Imprinting
- Ear Surgery and Otitis Media
- Cervical and Thoracic Myelopathy
- Congenital Anomalies and Fetal Surgery
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Facial Nerve Paralysis Treatment and Research
- Oral and Maxillofacial Pathology
- Spondyloarthritis Studies and Treatments
Port Said University
2019-2024
Hôpital Charles-Nicolle
2003-2024
Faculté de médecine de Tunis
2020-2024
Mansoura University
2022-2024
Tunis El Manar University
2014-2023
Tunis University
2014-2023
Riyadh Elm University
2022
King Saud University
2022
South Valley University
2022
Alfaisal University
2021
The global prevalence of COVID-19 disease and the overwhelming increase in death toll urge scientists to discover new effective drugs. Although drug discovery process is a challenging time-consuming, fortunately, plant kingdom was found have many active therapeutics possessing broad-spectrum antiviral activity including those candidates against severe acute respiratory syndrome coronaviruses (SARS-CoV). Herein, nine traditional Chinese medicinal constituents from different origins...
Obesity and diabetes are reaching epidemic levels globally. Metagenomics microbiome science have recently emerged as new tools for studying common complex human diseases. We report in this study notable differences gut adult patients with obesity Egypt. The experimental design was based on comparisons of four groups: (1) Controls (C) a normal body mass index, without or diabetes, (2) Obese adults (O) (3) (D) who not obese, (4) Adults both obese diabetic (OD). In total sample 60 participants,...
Radiotherapy-induced dermatitis (RID) is an inflammatory cutaneous disorder that acquired as adverse effect of undergoing radiotherapy. Skin microbiome dysbiosis has been linked to the outcomes several dermatological diseases. To explore skin microbiota RID and deduce their underlying impact on outcome RID, microbiomes 78 patients 20 healthy subjects were characterized by sequencing V1-V3 regions 16S rRNA gene. In total, a significantly apparent reduction in bacterial diversity was detected...
Abstract Background Streptococcus agalactiae or group B (GBS) asymptomatically colonizes the genitourinary tracts of up to 30% pregnant women. Globally, GBS is an important cause neonatal morbidity and mortality. has recently been linked adverse pregnancy outcomes. The potential interactions between vaginal microbiome composition remain poorly understood. In addition, little known about microbiota Egyptian Results Using V3-V4 16S rRNA next-generation sequencing, we examined in...
Rheumatoid arthritis (RA) is a chronic inflammatory disabling autoimmune disorder. Little known regarding the association between gut microbiome and etiopathogenesis of RA. We aimed to dissect differences in microbiomes associated with RA comparison healthy individuals and, addition, identify shifts bacterial community disease activity; Methods: In order compositional patients, V3-V4 hypervariable regions 16S rRNA were sequenced using Illumina MiSeq. total, sixty stool samples collected from...
Helicobacter pylori (H. pylori) is significantly linked to various diseases that seriously impact human health, such as gastric ulcers, chronic gastritis and adenocarcinoma.The compositional shifts in bacterial communities of the orointestinal axis were surveyed pre/post-eradication H. pylori. In total, 60 samples, including stool salivary specimens, collected from 15 pylori-positive individuals (HPP) before beginning 2 months after receiving eradication therapy. The V3-V4 regions 16S rRNA...
AI-driven pulse thermography (PT) has become a crucial tool in non-destructive testing (NDT), enabling automatic detection of hidden anomalies various industrial components. Current state-of-the-art techniques feed segmentation and depth estimation networks compressed PT sequences using either Principal Component Analysis (PCA) or Thermographic Signal Reconstruction (TSR). However, treating these two modalities independently constrains the performance inspection models as representations...
Colorectal cancer (CRC) is a public health concern and the second most common disease worldwide. This due to genetic coding influenced by environmental aspects, in which gut microbiota plays significant role. The purpose of this study was compare makeup CRC patients with that healthy control identify upregulated downregulated proteins metabolites patients. Using next-generation sequencing approach, fecal samples five females (4 one control) were analyzed BGI DNBSEQ-T7, Hong Kong, China....
<abstract> <p>One of the most prevalent malignancies that significantly affects world health is colorectal cancer (CRC). While genetics are involved in a portion CRC patients, cases sporadic. The microbiome composition could be new source tumor initiation and progression. This research was conducted to investigate microbiota patients post colectomy at taxonomic functional levels. Using next-generation sequencing approach, using an Illumina Novaseq 6000, fecal samples 13 were...
Purpose: To investigate the compositional and functional characteristics of T1DM-associated gut microbiota in two Egyptian cities to study geographical locality effects. Patients Methods: This case-control included 32 children with controlled T1DM 16 controls, selected from different regions Egypt. The both diabetic control was analyzed through 16S rRNA gene sequencing; this done using Illumina MiSeq platform. Results: Consistent findings among significantly lower alpha diversity than...
Introduction: New Delhi metallo-β-lactamase (NDM)-producing K. pneumoniae poses a high risk, especially among Egyptian pediatric patients who consume carbapenems antibiotics very widely and without adequate diagnostic sources. In addition, presence of efflux pump genes such as OqxAB increases resistance against many groups antimicrobials which exacerbates the problem faced for human health. This study aimed to determine NDM variants strains isolated from in Egypt, analyze genes, molecular...
Esophageal varices (EV) are serious complications of hepatitis C virus (HCV) cirrhosis. Endoscopic screening is expensive, invasive, and uncomfortable. Accordingly, noninvasive methods mandatory to avoid unnecessary endoscopy. Acoustic radiation forced impulse (ARFI) imaging using point shear wave elastography as demonstrated with virtual touch quantification a possible EV predictor. We aimed validate the reliability liver stiffness (LS) spleen (SS) by an ARFI-based study together other...
Mutations within the "a" determinant region (position 124-147) that is present in major hydrophilic (MHR, position 99-160) of hepatitis B surface antigen (HBsAg) are associated with vaccine-escape, lack diagnosis, and failure to immunoglobulin (HBIG) therapy. Data regarding amino acid changes HBsAg limited Egypt. The prevalence mutations this among chronic HBV (CHB)-infected patients Upper Egypt not known.Blood samples were collected from HBsAg-positive CHB-infected (n=123) admitted Assiut...
Hydatid disease is an endemic echinococcal infestation in Tunisia. Only 4% of hydatid cysts are located the muscle. The gluteal localization a very rare entity. present case illustrates cyst resulting sciatica and osteonecrosis femoral head, exceptional entity.A 49-year-old man urban origin, with free medical history, presented to our outpatient clinic left mechanical hip pain, that have been ongoing for 2 years. Pelvic radiograph showed head lytic lesions ischium. MRI scan identified...
Background: Because of vital features including biocompatibility, high surface reactivity, and oxidation resistance, emerging nanomedicine is well-known for its potential therapeutic prospects. The goal this study to see if nanoparticle zinc oxide (ZnONPs) may reduce hepatic problems oxidative stress in rats with diabetes mellitus induced by streptozotocin (STZ). Materials methods: This included 39 separated into three groups, each consisting 13 rats; control group, + ZnONPs group....
Background and purpose The magnitude of the coronavirus disease 2019 (COVID-19) pandemic on healthcare system, economy, education, social networking is dreadful, least to say. Surprisingly, unlike previous epidemics, impact has been universal, even top-ranking countries with solid economies were not immune. this study develop a better understanding Saudi community's response reaction preventative measures implemented by government combat COVID-19 pandemic. Methodology A cross-sectional using...
<h3>ABSTRACT</h3> Osteoid osteoma (OO) is a benign tumor that usually occurs in long bones of young males. We report rare case spinal OO 25-year-old woman, revealed by sciatica. Spinal radiographs and computed tomography scan were normal, although performed at 6 months symptom evolution. On magnetic resonance imaging, however, an important edema the right transverse process L5 vertebrae was depicted but inconclusive. The diagnosis finally retained on second with thinner slices focused...
Quorum-sensing is a phenomenon of intercellular messages in microorganisms through secretion small signaling molecules, which spread between cells, facilitating communication, and regulating virulence factors production. system disruption Pseudomonas aeruginosa identifying new inhibitors promising approach. Herein, we test the possible quorum-sensing inhibitory effect esomeprazole, proton pump inhibitor, on standard strain PAO1. The production controlled violacein pigment biosensor...
<h3>Background</h3> Although it still remains a rare disease, spondylodiscitis has been on the rise in past decades. Early diagnosis can be difficult, but Improved diagnostic techniques and modern treatments have reduced patient mortality. However, studies reporting outcome of are scarce. <h3>Objectives</h3> To assess influence functional impairment mental health patients surgically treated for spondylodiscitis. <h3>Methods</h3> A prospective study was carried out over two-year period at...
Abstract Background Cytokines play a crucial role in regulating the function of immune system by controlling production, differentiation, and activity cells. Occult hepatitis C virus (OHCV) infection can lead to liver damage, including cirrhosis hepatocellular carcinoma. This study investigates immunopathogenic impact cytokines IL-17 IL-22 OHCV compared chronic (CHC) infection. Methods We studied three groups patients: 35 with OHCV, 100 untreated patients CHC, 30 healthy control subjects....