A5087446731- Chronic Obstructive Pulmonary Disease (COPD) Research
- Esophageal and GI Pathology
- Lipid metabolism and disorders
- Gastrointestinal Tumor Research and Treatment
- Ovarian cancer diagnosis and treatment
- Extracellular vesicles in disease
- Metastasis and carcinoma case studies
- Iron Metabolism and Disorders
- Cell Adhesion Molecules Research
- Prostate Cancer Treatment and Research
- Pediatric Hepatobiliary Diseases and Treatments
- Abdominal vascular conditions and treatments
- Hemoglobinopathies and Related Disorders
- Liver Disease Diagnosis and Treatment
- Infectious Aortic and Vascular Conditions
- Clostridium difficile and Clostridium perfringens research
- Esophageal Cancer Research and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Biomedical Ethics and Regulation
- Vascular Procedures and Complications
- Eosinophilic Esophagitis
- Cancer, Hypoxia, and Metabolism
- Colorectal and Anal Carcinomas
- Erythropoietin and Anemia Treatment
- Appendicitis Diagnosis and Management
Sanofi (United States)
2024
Baylor College of Medicine
2017-2021
St. Luke's Hospital
2021
Michael E. DeBakey VA Medical Center
2018-2019
University of Toronto
2016-2017
St. Joseph's Hospital
2013
McMaster University
2013
Poole Hospital
2010
Crawley Hospital
1999-2001
PTEN is a potent tumor-suppressor protein. Aggressive and metastatic prostate cancer (PC) associated with reduction or loss of expression. often occurs without gene mutations, its downregulation not fully understood. Herein, we show that incorporated in the cargo exosomes derived from cells. detected normal, noncancerous We found can be transferred to other cells through exosomes. In have complete expression, competent confer tumor-suppression activity acceptor PC patients, circulate their...
Abstract Background: Although several serum markers of ovarian cancer (OVCA) have been suggested, none can detect OVCA at early stage specifically because the lack a corresponding marker in ovary. Ovarian malignant cellular transformation is an event followed by tumor-associated neoangiogenesis (TAN). Malignant results shedding nuclear matrix proteins (NMPs) circulation and anti-NMP autoantibody production. VEGFR-2, TAN marker, may also be imaging for detection. Thus VEGFR-2 association with...
An 8-year-old boy with Asperger9s syndrome presented right-sided abdominal pain, which was consistent a probable appendicitis, but revisiting the history high index of suspicion confirmed multiple foreign body ingestion to be cause his symptoms. emergency laparotomy performed. Multiple toy magnets and other metal objects were found, causing small bowel obstruction interloop fistulation. Following removal repair, patient made an excellent recovery.
Answers on p 130. A 52 year old woman presented with a two day history of worsening central abdominal pain, nausea, and vomiting. Over the previous month she had been treated for flare up …
Introduction: Appendiceal goblet cell adenocarcinoma (GCA) is among the rarest tumors with an incidence reported at 0.05 cases per 100,000. There have only been 369 over a 30-year span from 1970s. Even though these stain positive for neuroendocrine markers, they behave more aggressively like conventional adenocarcinomas. GCA most commonly presents as appendicitis and discovered incidentally after appendectomy. This case reports unique presentation of behaving Crohn’s disease interesting...
The most common complications of choledocolithiasis include pancreatitis and cholangitis; however, the rare complication enterobiliary fistulas may occur. It is reported that 68% present as cholecysto-duodenal, 13.6% cholecysto-colonic, 8.6% choledoco-duodenal. Very scant cases have occurrence choledoco-colonic (CDCF). Our case reports extremely phenomenon a CDCF complicated by pyogenic hepatic abscess all in setting choledocolithiasis. A 54 year old man presented with nausea, vomiting,...
Malignancy within the duodenum is an infrequent encounter accounting for less than 0.4% of all cancers. Metastatic lesions from malignant melanoma and adenocarcinomas pancreas, lung, stomach, colon are most common. Carcinoma cervix typically spreads via direct extension, but nodal metastases not uncommon. This case reports extremely rare location cervical cancer duodenum. A 54 year old female Honduras presented with anorexia, early satiety, weight loss several months. She was reportedly...
INTRODUCTION: Head and neck radiation therapy is known to cause esophagitis esophageal strictures as early late effects after exposure, respectively. The negative of on motor function have been speculated in case reports but not studied a larger population with high resolution manometry (HRM). aim this study was evaluate HRM findings patients who received head or mediastinal presented symptoms. METHODS: There were total 718 from 2010 2018 at the Michael E. DeBakey VA Medical Center. Patients...
Introduction: Rectal perforation is a known complication of radical prostatectomy reported to occur in 0.3-3.8% cases. Primary closure and diverting ileostomy are immediately performed; however, it not uncommon see persistent rectal defect after surgical repair. The use endoscopic vacuum therapy (EVT) has shown increasingly favorable results with gastrointestinal (GI) perforations. EVT most commonly used for esophageal leaks perforations given abundant literature demonstrating successful...
Introduction: Barrett's esophagus (BE) is a well-established precursor to esophageal adenocarcinoma (EAC). The presence of dysplasia in BE significantly increases the risk EAC. Current guidelines recommend radiofrequency ablation (RFA) for treatment dysplastic BE. Patients require an average 4-5 RFA sessions and it not uncommon observe small islands residual after initial sessions. When was first introduced at our tertiary care medical center, these were often treated with APC. Methods: We...