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Contact & Profiles
A5020108693
Research Areas
- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
Soochow University
2022
First Affiliated Hospital of Soochow University
2022
Abstract Metastasis is an important factor contributing to poor prognosis in patients with gastric cancer; yet, the molecular mechanism leading this cell behavior still not well understood. In study, we explored role of cysteine protease inhibitor SN (Cystatin SN, CST1) promoting cancer metastasis. We hypothesized that CST1 could regulate progression by regulating GPX4 and ferroptosis. Whole transcriptome sequencing suggested expression was significantly increased metastatic cancer, high...
10.1038/s41388-022-02537-x
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Oncogene
2022-11-12
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