A5006061039- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Genital Health and Disease
- HIV/AIDS drug development and treatment
- Gestational Diabetes Research and Management
- Tuberculosis Research and Epidemiology
- Cytomegalovirus and herpesvirus research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sexual function and dysfunction studies
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Viral Infections and Outbreaks Research
- Cervical Cancer and HPV Research
- Bacillus and Francisella bacterial research
- Drug-Induced Hepatotoxicity and Protection
- Tryptophan and brain disorders
- Hepatitis C virus research
- Polyomavirus and related diseases
- Poxvirus research and outbreaks
- Adolescent Sexual and Reproductive Health
- SARS-CoV-2 and COVID-19 Research
Imperial College London
2022-2025
Imperial College Healthcare NHS Trust
2023-2025
NIHR Imperial Biomedical Research Centre
2024-2025
St Mary's Hospital
2023-2024
St. Mary's Hospital
2024
St Mary's Hospital
2023
Northwick Park Hospital
2020
London North West Healthcare NHS Trust
2020
In resourced settings, adults living with perinatally acquired HIV are approaching the 5th decade of life. Their clinical and psychological outcomes highlight potential future issues for much larger number adolescents growing up in sub–Saharan Africa, will inform development appropriate healthcare services. Lifelong exposure to HIV, increasingly antiretroviral therapy throughout growth development, contrasts acquiring later This review describes including post transition mortality, morbidity...
Introduction The BIC-T&T study aimed to determine the efficacy of bictegravir/emtricitabine/tenofovir alafenamide (BIC/F/TAF) and darunavir/cobicistat/emtricitabine/tenofovir (DRV/c/F/TAF) at suppressing viral load in a two-arm, open-label, multi-centre, randomised trial under UK test-and-treat setting. This sub-study evaluate potential off-target cardiovascular impact by examining ex vivo platelet function.
Abstract Objectives Human papillomavirus (HPV)‐associated cervical cancer risk is greater in people with HIV, although this has been at least partially attenuated by antiretroviral medication, enhanced screening and HPV vaccination. People perinatally acquired HIV may remain higher due to lifelong immunosuppression potentially reduced vaccine effectiveness. In study a cervix we explored high‐risk (hrHPV) prevalence serostatus. Methods Participants were recruited from London service between...
Our objectives were to investigate the recent frequency of cerebrospinal fluid (CSF) HIV RNA escape and other CSF viral nucleic acid detection in people with neurological symptoms assess associated clinical factors.This was a retrospective cohort analysis who underwent examination for indications between 2017 2022. Individuals identified from pathology records, data recorded. defined as concentrations greater than plasma. screen included herpes simplex virus types 1 (HSV-1) 2 (HSV-2),...
Head-to-head data for bictegravir/emtricitabine/tenofovir alafenamide (BIC/F/TAF; B) and darunavir/cobicistat/emtricitabine/tenofovir (DRV/c/F/TAF; D) are lacking in the context of rapid antiretroviral therapy (ART) initiation. This study, BIC-T&T, evaluates efficacy tolerability B vs D a UK test-and-treat setting.
The International AIDS Society convened a multidisciplinary committee of experts in December 2020 to provide guidance and key considerations for the safe ethical management clinical trials involving people living with HIV (PLWH) during SARS-CoV-2 pandemic. This consultation did not discuss design prevention studies at risk acquisition, nor programmatic delivery antiretroviral therapy (ART).There is strong ambition continue research from both PLWH community despite ongoing How do this safely...