A5073423656- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Trypanosoma species research and implications
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Heme Oxygenase-1 and Carbon Monoxide
- Sex work and related issues
- Research on Leishmaniasis Studies
- Rabies epidemiology and control
- Parasites and Host Interactions
- Legionella and Acanthamoeba research
- Parasitic infections in humans and animals
- Maternal and Neonatal Healthcare
- Zoonotic diseases and public health
- Parasitic Diseases Research and Treatment
- Malaria Research and Control
- Science and Education Research
- Parvovirus B19 Infection Studies
- Travel-related health issues
- Reproductive Health and Technologies
- Pediatric health and respiratory diseases
- Insect symbiosis and bacterial influences
- Helminth infection and control
- Male Reproductive Health Studies
- Public Health in Brazil
Universidade Federal de Goiás
2014-2025
Universidade Evangelica de Goiás
2022
Universidade de Rio Verde
2022
Instituto de Saúde
2020
Universidade Federal de Minas Gerais
2018
Instituto de Medicina Tropical
2015
Public Health Institute
2014-2015
Universidade de Brasília
2003-2004
Background A century after its discovery, Chagas disease still represents a major neglected tropical threat. Accurate diagnostics tools as well surrogate markers of parasitological response to treatment are research priorities in the field. The purpose this study was evaluate performance PCR methods detection Trypanosoma cruzi DNA by an external quality evaluation. Methodology/Findings An international collaborative launched expert laboratories from 16 countries. Currently used strategies...
Introduction Toxoplasmosis is a parasitary disease that presents high rates of gestational and congenital infection worldwide being therefore considered public health problem neglected disease. Objective To determine the prevalence toxoplasmosis amongst pregnant women vertical transmission Toxoplasma gondii in their newborns attended Basic Units Health (BUH) from city Gurupi, state Tocantins, Brazil. Methods A study was performed, including 487 BUH urban zone Brazil, during period February...
Control programs have been executed in an attempt to reduce vertical transmission and the severity of congenital infection regions with a high incidence toxoplasmosis pregnant women. We aimed evaluate whether treatment women spiramycin associated lack monitoring for seroconversion affects prognosis patients. performed prospective cohort study 246 newborns (NB) at risk Goiânia (Brazil) between October 2003 2011. analyzed efficacy maternal spiramycin. A total 40.7% (66/162) neonates were born...
OBJECTIVES: Determine the risk factors involved in toxoplasmosis transmission and determine whether pregnancy is a factor for infection. STUDY DESIGN: Cross-sectional study carried out on 2,242 women at childbearing age. An indirect immunofluorescence reaction was used to identify immunity Toxoplasma gondii. Previous gestations were also analyzed as possible factor. The results by chi2 OR tests, variance analysis. sample statistically balanced according social-economic factors. RESULTS:...
Objetivo: Identificar fatores que contribuem para a subnotificação de doenças e agravos notificação compulsória no Sistema Nacional Agravos Notificação (Sinan), na percepção dos profissionais saúde. Métodos: Estudo conduzido com base Técnica Incidentes Críticos coleta dados análise conteúdo, em uma amostra estratificada trabalhadores gestores das unidades vigilância saúde responsáveis pelas notificações compulsória. Resultados: Os casos relatados associaram-se 33 os principais comportamentos...
ABSTRACT Our research aimed to characterize the genetic profiles of 102 Trypanosoma cruzi isolates recently obtained from 44 chronic chagasic patients different regions states Minas Gerais and Goiás in Brazil. At least two were each patient at times order study parasite population dynamics during disease progression phase. The characterized molecularly by genotyping 3′ region 24Sα rRNA, mitochondrial cytochrome oxidase subunit 2 (COII) gene, intergenic spliced leader (SL-IR) gene....
Introduction Knowledge of the prevalence and risk factors for Toxoplasma gondii dissemination among pregnant women is relevant because parasite can be spread from mother to infant. The objective this study was assess epidemiology toxoplasmosis in Gurupi, State Tocantins, Brazil, February 2012 June 2013. Methods population included 487 women. Sociodemographic, dietary cultural data were collected using a standardized validated form. Peripheral blood serologic testing ELISA test (IgM/IgG...
One hundred fifty-two Trypanosoma cruzi seropositive women were submitted to a single hemoculture; 101 pregnant, and 51 not pregnant. Seven tubes from each individual harvested with liver infusion tryptose (LIT) medium observed monthly until the fifth month. Hemocultures positive in 50% (76 of 152) women. Results showed that positivity was 29.4% (15 51) among non-pregnant 60.4% (61 101) pregnant (P < 0.05). In relation gestational age, there significant differences positivity, higher...
The different laboratory methods used in the diagnosis of congenital toxoplasmosis have variable sensitivity and specificity. There is no evidence to prove that maternal treatment reduces risk fetal infection. purpose this study was assess for confirmation after with spiramycin during pregnancy, evaluate effect on clinical manifestations disease newborns (NB).This a community-based, cross-sectional acute at acquiring Participating were born Clinical Hospital Maternity Ward Federal University...
To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention gestational during prenatal care. The had a previous serological diagnosis conducted care, with non-reactive (<10 IU/mL) IgM and reactive IgG (>10 IU/mL), were considered "immune" infection. Both sequelae infection, including neurological ocular alterations. Managing susceptible pregnant women is considerable challenge several...
A toxoplasmose e sua transmissão congênita são questões de saúde pública importantes no Brasil. No entanto, a falta instrumentos validados que avaliem percepção desses grupos sobre doença dificulta implementação estratégias educação prevenção adequadas.Este trabalho objetivou construção validação questionários poderão ser utilizados para avaliar profissionais gestantes da infecção.A seleção dos painelistas ocorreu por amostragem intencional. O Método Delphi foi utilizado padronização dois...
A toxoplasmose é uma infecção altamente prevalente e um problema de saúde pública. atovaquona droga potencial para o tratamento, mas ainda não faz parte dos protocolos terapêuticos atuais. Este estudo teve como objetivo avaliar, in vitro, as concentrações metabólitos orgânicos do ciclo ácido tricarboxílico (TCA), catabolismo ácidos graxos proteínas analisar metabolismo taquizoítos das cepas RH ME49 Toxoplasma gondii sua resposta após a exposição à atovaquona. O parasita foi cultivado em...
The immune response is crucial for protection against disease; however, immunological imbalances can lead to heart and digestive tract lesions in chagasic patients. Several studies have evaluated the cellular humoral responses patients an attempt correlate findings with clinical forms of Chagas disease. Moreover, immunoglobulins cytokines are important parasitic control involved lesion genesis. Here, cytokine IgG isotype production were studied, using total epimastigote antigen on sera...
PURPOSE: To compare salivary and serum cortisol levels, alpha-amylase (sAA), unstimulated whole saliva (UWS) flow rate in pregnant non-pregnant women. METHOD: A longitudinal study was conducted at a health promotion center of university hospital. Nine 12 women participated the study. Serum UWS were collected analyzed every trimester twice month during menstrual cycle. The levels determined by chemiluminescence assay sAA processed an automated biochemistry analyzer. RESULTS: Significant...
OBJETIVO: Determinar a prevalência de toxoplasmose e identificar os principais fatores associados à sororeatividade em gestantes atendidas dois centros referência uma cidade do Nordeste Brasil. MÉTODOS: Foi realizado um estudo transversal com 561 para pré-natal alto risco Todas foram entrevistadas por meio questionário epidemiológico coletadas amostras sangue que realizadas sorologia anti-Toxoplasma gondii IgG IgM (ELISA), teste avidez da reação cadeia polimerase (PCR). A análise estatística...
Knowledge of the epidemiological profile and risk factors for Toxoplasma gondii infection among postpartum women is a relevant issue, because this protozoan can be vertically transmitted to developing fetus, which cause severe debilitating disease. The aim study was assess associated with T. in Goiânia, GO, Brazil.This cross-sectional comprised 229 women, whom 204 were chronically infected (IgG+/IgM-), 25 seronegative (IgG-/IgM-; control group). All patients asked complete form provide...
The goal of this study was to investigate the importance IgG avidity testing in newborns (NBs) diagnosed with early congenital toxoplasmosis. We collected samples from 88 puerperae infected by Toxoplasma gondii (T. gondii) and their NBs (48 acutely-infected (AIP) 40 chronically-infected (CIP)), two public maternity hospitals Goiania city, Goias, Brazil, 2010 2015. Specific anti-T. IgM serum levels tests were evaluated using chemiluminescence. Congenital toxoplasmosis observed 66.66% (n = 32)...
Calcium is considered an essential element for the metabolism of aquatic snail Biomphalaria glabrata (Say, 1818), intermediate host Schistosoma mansoni Sambon, 1907 in Brazil, and represents a limiting factor to its distribution adaptation environment. This study investigated effect different concentrations exogenous CaCO3 on energetic B. better understanding physiological interference chemical elements dissolved environment with physiology this species. Sixty-day-old snails were distributed...
We report an Acanthamoeba keratitis case associated with the use of contact lens in a 28-year-old female from Brasília, Brazil. Samples corneal scraping and were used for culture establishment, PCR amplification, partial sequencing (fragments ~400kb) small subunit rDNA; both positive. The sequence analyses cornea isolates showed similarity T4 genotype. To best our knowledge, this is first Midwest region
Leishmaniasis is a complex disease that affects mammals and caused by approximately 20 distinct protozoa from the genus Leishmania . an endemic exerts large socioeconomic impact on poor developing countries. The current treatment for leishmaniasis complex, expensive, poorly efficacious. Thus, there urgent need to develop more selective, less expensive new drugs. energy metabolism pathways of include several interesting targets specific inhibitors. In present study, we sought establish which...