A5100318927- Metabolomics and Mass Spectrometry Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Genomics and Phylogenetic Studies
- Multiple Myeloma Research and Treatments
- Gut microbiota and health
- Renal cell carcinoma treatment
- Chronic Kidney Disease and Diabetes
- Traditional Chinese Medicine Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Renal Diseases and Glomerulopathies
- Complement system in diseases
- Cancer-related gene regulation
- Platelet Disorders and Treatments
- MicroRNA in disease regulation
- Chemical Synthesis and Reactions
- CRISPR and Genetic Engineering
- Hemophilia Treatment and Research
- Peptidase Inhibition and Analysis
- Systemic Lupus Erythematosus Research
- Bacteriophages and microbial interactions
- Ginseng Biological Effects and Applications
- Medical Research and Treatments
- Alcohol Consumption and Health Effects
- Clostridium difficile and Clostridium perfringens research
- Body Contouring and Surgery
Guangxi Medical University
2023-2024
Union Hospital
2018-2023
Fujian Medical University
2018-2023
Guiyang Medical University
2022
Jilin University
2022
Xinjiang Medical University
2017
Blood Systems Research Institute
2015
University of California, San Francisco
2015
Urumqi General Hospital of PLA
2010
Abstract Next-generation sequencing (NGS) approaches rapidly produce millions to billions of short reads, which allow pathogen detection and discovery in human clinical, animal environmental samples. A major limitation sequence homology-based identification for highly divergent microorganisms is the length reads generated by most parallel technologies. Short require a high level similarities annotated genes confidently predict gene function or homology. Such recognition homologues can be...
The simple and easily prepared Brønsted acidic ionic liquid (BAIL) could act as both the solvent catalyst be recovered reused at least six times without considerable loss in catalytic activity. Moreover, direct amidation of carboxylic acids amines a stoichiometric proportion catalyzed efficiently by BAIL with broad substrate scope, multigram scale, significant sustainability improvement [scalable up to 100 mmol, (process mass intensity) PMI (reaction purification) < 3]. Notably, water formed...
Abstract Background Renal impairment (RI) is associated with poor survival in newly diagnosed multiple myeloma (MM) patients. function recovery has been one of the main therapeutic goals those Methods The records from 393 MM patients our hospital between January 2012 and December 2016 were retrospectively analyzed. RI was defined as an eGFR < 40 mL/min according to novel IMWG criteria. categorized based on their renal at diagnosis: severe RI: 30 mL/min, mild ≤ <40 mL/min. We explored...
Abstract Free fatty acids (FFAs) participate in a variety of physiological functions. FFAs are associated with the development type 2 diabetes mellitus (T2DM). Uyghurs and Kazaks have different prevalence T2DM, which cannot be explained by traditional risk factors. This study aimed to examine as potential biomarkers distinguish between healthy T2DM Kazaks. was prospective conducted at Xianjiang Medical University from 01/2007 06/2010 The subjects were grouped patients (Uyghurs: n=39; Kazaks,...
Type XXVIII collagen (COL28) is involved in cancer and lung fibrosis. COL28 polymorphisms mutations might be kidney fibrosis, but the exact role of renal fibrosis unknown. This study explored function tubular cells by examining expression mRNA effects overexpression human cells. localization were observed normal fibrotic tissues from humans mice using real-time PCR, western blot, immunofluorescence, immunohistochemistry. The consequences on cell proliferation, migration, polarity,...
Coronary artery disease (CAD) is one of the leading threats to global health. Previous research has proven that metabolic pathway disorders, such as high blood lipids and diabetes, are risk factors mostly cause CAD. However, crosstalk between pathways CAD was studied on physiology processes by analyzing a single gene function. A canonical correlation analysis used identify pathways, which were integrated unit coexpress with susceptibility genes, resolve additional related Seven including...
To study the effect of exogenous Ca2+ on photosynthetic parameters Pinellia ternate and accumulations active components under high temperature stress.The pigment contents P. ternata leaves, photosynthesis chlorophyll fluorescence guanosine, adenosine polysaccharide in tubers were measured based different concentrations heat stress when plant height was around 10 cm.The total ratio a/b relatively higher by spaying Ca2+. Compared with control, 6 mmol x L(-1) significantly enhanced net rate...
A novel collagen called type XXVIII (COL28) is involved in cancer and lung fibrosis. Preliminary data showed that renal tubular epithelial cells could proliferate, migrate, undergo an epithelial-mesenchymal transition (EMT) when COL28 was overexpressed; however, it still unknown how this occurs what the underlying mechanism is.We analyzed differential expression of genes (DEGs) stable overexpression HK-2 cell lines by RNA-sequencing analysis, before which Gene Ontology (GO) Kyoto...
To analyze the effect of serum free light chain (sFLC) on renal function and prognosis in patients with newly diagnosed multiple myeloma (MM).The clinical data 70 MM who received sFLC examination Fujian Medical University Union Hospital were retrospectively analyzed from April 2012 to November 2016. Univariate analysis was used risk factors that associated impairment (RI) prognosis. Logistic regression Kaplan-Meier roles RI prognosis.Out patients, 20 had at initial diagnosis. Compared normal...