A5100417546- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Migraine and Headache Studies
- Sepsis Diagnosis and Treatment
- Machine Learning in Healthcare
- Sesquiterpenes and Asteraceae Studies
- Neurological diseases and metabolism
- Cancer and Skin Lesions
- Forensic Toxicology and Drug Analysis
- Neurological and metabolic disorders
- Reconstructive Surgery and Microvascular Techniques
- Genetic Neurodegenerative Diseases
- Nasolacrimal Duct Obstruction Treatments
- Methemoglobinemia and Tumor Lysis Syndrome
- Neurofibromatosis and Schwannoma Cases
- Genital Health and Disease
- Liver Diseases and Immunity
- Ocular Surface and Contact Lens
- Pediatric Hepatobiliary Diseases and Treatments
- Foreign Body Medical Cases
- Acute Kidney Injury Research
- Coleoptera Taxonomy and Distribution
Hospital Beatriz Ângelo
2025
Hospital de São João
2024
University of Coimbra
2012-2023
Hospitais da Universidade de Coimbra
2018-2023
Association for Innovation and Biomedical Research on Light and Image
2012
Universidade Federal de Santa Catarina
2008
University of Chile
2003
Aims The aim of this study was to describe femoral head reduction osteotomy (FHRO) and review its safety, the radiological correction which may be obtained, clinical results at a minimum follow-up two years. Methods A total 12 patients (12 hips) with severe deformity head, mainly from Perthes’ disease, underwent FHRO using surgical hip dislocation technique an extended retinacular flap. Their mean age 17 years 25). Radiographs were obtained before after surgery evaluate morphological...
Cantharidin is a poisonous substance secreted by blister beetles, including the 'Spanish fly'. Historically, cantharidin was used as an aphrodisiac, vesicant and abortifacient. Symptoms of poisoning include gastrointestinal genitourinary mucosal irritation along with renal dysfunction. We present case reckless 23-year-old soldier who accepted challenge eating beetle (Berberomeloe majalis). Six hours later he admitted to emergency room abdominal pain, dysuria, gross haematuria clots,...
We recently showed that a single high dose of methamphetamine (METH) induces persistent frontal cortical monoamine depletion is accompanied by helpless-like behavior in mice. However, brain metabolic alterations underlying both neurochemical and mood remain unknown.Herein, we aimed at characterizing associated with early negative triggered METH. Adult C57BL/6 mice were injected METH (30 mg/kg, i.p.), their status was characterized after probing anxiety-related phenotypes 3 days...
A 30-year-old man, forestry worker, with no medical history, presented acutely pruritic erythematous streaks and bullae (figure 1) in linear configuration on his arms. On the previous day he had pruned branches from a fig tree carried them forearms wearing sleeveless shirt. Symptoms gradually resolved over 4 weeks of topical treatment clobetasol propionate 0.05% cream 2). Figure 1 Bullae irregular pigmented lesions both …
Although foreign body ingestion is a common occurrence, perforation and penetration of the gastrointestinal tract unusual development hepatic abscess even more rare. The authors describe two cases fish bone with formation, from distinctive age groups varying presentation, although both developed septic shock. lack history bodies, non-specificity clinical presentation complementary examinations all play role in delaying diagnosis therefore prognosis itself.
A 22-year-old man presented with a 24-hour history of bilateral lumbar pain, abdominal nausea, fever and difficulty walking. Two months before he had similar complaints. The patient no significant medical except for car accident 6 years left lower limb trauma without
Acute intermittent porphyria (AIP) is a rare condition, metabolic disorder of the haem biosynthesis. An acute crisis AIP can present as combination symptoms, such abdominal pain, autonomic dysfunction, hyponatremia, muscle weakness and neurological symptoms in absence others obvious causes. We report case 53-year-old woman, who was previously diagnosed with 5 weeks after therapeutic suspension has developed an disease exacerbation. During hospitalisation, further exacerbation occurred...
Autoimmune hepatitis (AIH) is a rare chronic liver disease with non-specific clinical presentation. Its physiopathology not fully understood and, if untreated, can progress to cirrhosis and even fulminant failure. Here, we describe case of 73-year-old patient an 11-month history suggestive disease, who was concomitantly diagnosed AIH the extremely postinfantile giant cell (PIGCH). Despite standard immunosuppressive therapy, presented severe course, culminating in acute-on-chronic failure...
A enxaqueca é uma doença neurovascular caracterizada por sintomas de cefaleia intensa unilateral com fonofobia e fotofobia afetando cerca 15,8% das pessoas no Brasil onde em sua maioria são mulheres. O uso anticoncepcionais orais combinados pode aumentar o risco AVC gera-se as crises enxaqueca. Como hipótese estuda-se métodos contraceptivos pioram os maior frequência intensidade quando comparados às que utilizam outros ou não utilizam. Nos resultados discussão podemos perceber AOC tem forte...
Se presentan 5 pacientes con un cuadro clinico de degeneracion corticobasal (DCB); son los primeros casos publicados en nuestro pais. Todas eran mujeres la 6a o 7a decada vida; 4 distonia comenzo por el brazo derecho. El curso fue lentamente progresivo, parkinsonismo (rigidez, akinesia, alteraciones posturales y disartria), demencia tipo frontal apraxias (constructiva todas, ideomotora bilateral oral una, defecto motor impidio su evaluacion varios casos). En dos se comprobo una afasia no...
Abstract Background: The use of non-invasive positive pressure ventilation (NIPPV) in COVID-19 patients with hypoxaemia is still under debate. aim was to evaluate the efficacy NIPPV (CPAP, HELMET-CPAP or NIV) treated dedicated Intermediate Care Unit Coimbra Hospital and University Centre, Portugal, assess factors associated failure. Patients admitted from December 1st 2020 February 28th 2021, due were included. Failure defined as orotracheal intubation (OTI) death during hospital stay....
Abstract Background The use of non-invasive positive pressure ventilation (NIPPV) in COVID-19 patients with hypoxaemia is still under debate. aim was to evaluate the efficacy NIPPV (CPAP, HELMET-CPAP or NIV) treated dedicated Intermediate Care Unit Coimbra Hospital and University Centre, Portugal, assess factors associated failure. Methods Patients admitted from December 1st 2020 February 28th 2021, due were included. Failure defined as orotracheal intubation (OTI) death during hospital...