A5100377776- Functional Brain Connectivity Studies
- 3D Printing in Biomedical Research
- Autophagy in Disease and Therapy
- Advanced MRI Techniques and Applications
- Phytochemicals and Antioxidant Activities
- Innovative Microfluidic and Catalytic Techniques Innovation
- Anesthesia and Pain Management
- Sirtuins and Resveratrol in Medicine
- Glioma Diagnosis and Treatment
- Neuroscience and Neuropharmacology Research
- Epilepsy research and treatment
- Advanced Neuroimaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Nausea and vomiting management
- Memory and Neural Mechanisms
- Sesame and Sesamin Research
- Migraine and Headache Studies
- Cannabis and Cannabinoid Research
- Dementia and Cognitive Impairment Research
- RNA modifications and cancer
- Sleep and Wakefulness Research
- Pain Management and Opioid Use
- Genomics, phytochemicals, and oxidative stress
- Hearing, Cochlea, Tinnitus, Genetics
- Mental Health Research Topics
Ningxia Medical University
2024-2025
Air Force Medical University
2021-2025
Soochow University
2025
Anhui University of Traditional Chinese Medicine
2025
Harbin Medical University
2020-2025
Hebei University
2024
Nanjing Brain Hospital
2023-2024
Nanjing Medical University
2023-2024
Zhejiang University
2016-2024
The University of Texas MD Anderson Cancer Center
2017-2024
Humans are inevitably exposed to ethyl carbamate (EC) via consumption of fermented food and beverages. EC, known as an environmental toxin, can cause oxidative stress-mediated severe toxicity, but the underlying mechanisms remain unveiled. Ferroptosis is a newly identified ROS-mediated non-apoptotic cell death characterized by iron accumulation excessive lipid oxidation. In this study, we first found that EC triggered ferroptosis in liver cells detection decreased viability, GSH, GPX4...
Mulberry has attracted wide attention due to its substantial nutritional values. This work first studied the protective effect of mulberry anthocyanins (MAS) on dextran sulfate sodium (DSS)-induced colitis. The mice experiment was designed as four groups including normal (Control), (DSS)-fed mice, and DSS plus 100 mg/kg·bw MAS-fed (LMAS-DSS) or 200 (HMAS-DSS). Mice were given MAS by gavage for 1 week, then added drinking water 7 days. administered a total 17 results showed that oral reduced...
Increasing evidence indicates that anthocyanins exert beneficial effects on type 2 diabetes (T2D), but the underlying mechanism remains unclear. Herein, hyperglycemia-lowering effect of Pg3G derived from wild raspberry was investigated high-glucose/high-fat (HG+HF)-induced hepatocytes and db/db diabetic mice. Our results indicated promoted glucose uptake in HG+HF-induced hepatocytes. Moreover, induced autophagy, whereas autophagy inhibitors blocked hypoglycemic Pg3G. Transcriptional factor...
Rotator cuff tears are the most common conditions in sports medicine and attract increasing attention. Scar tissue healing at tendon-bone interface results a high rate of retears, making it major challenge to enhance rotator interface. Biomaterials currently employed for still exhibit limited efficacy. As promising technology, 3D printing enables customization scaffold shapes properties. Bone marrow mesenchymal stem cells (BMSCs) have multidifferentiation potential valuable immunomodulatory...
Organ-on-a-chip technology, a promising three-dimensional (3D) dynamic culture method, ensures accurate and efficient cell has great potential for replacing animal models in preclinical testing. The circulatory system, the most abundant organ human body, plays crucial role oxygen exchange mass transfer, which is determining factor survival of tissues organs. Thus, it essential to integrate system into an organ-on-a-chip recreate tissue microenvironments physiological functions. This review...
Nonalcoholic fatty liver disease (NAFLD) has become a universal health issue, whereas there is still lack of widely accepted therapy until now. Clinical research studies have shown that blueberry could effectively regulate the lipid metabolism, thereby improving obesity-related metabolic syndromes; however, specific active substances and mechanisms remain unclear. Herein, effects major 10 kinds anthocyanins from against NAFLD were investigated using an free acid (FFA)-induced cell model....
Abstract The detection of biomolecules utilizing surface‐enhanced Raman spectroscopy (SERS) is highly trending in research, but the unlabeled and sensitive saccharides body fluids challenging. Here, a novel SERS substrate (AgNS 600 ) fabricated by physical scratching smooth silver sheets, which successfully achieves enhanced fingerprinting capturing glucose molecules through nanoscale grooves on surface to form multi‐dimensional “hot spot” regions. platform proves be rapid, reliable,...
Pelargonidin-3-O-glucoside (Pg) is a well-known anthocyanin derivative possessing potential biological activity. Nonetheless, the bioactivity of Pg limited due to instability in physiological environment. Functionalized nanoliposomes using chitosan and/or pectin coating an excellent carrier system for nanoencapsulation food bioactive compounds such as Pg. Therefore, this study aimed investigate protective effect Pg-loaded pectin-chitosan coated against palmitic acid (PA)-induced hepatocytes...
The purpose of the current study was (1) to develop a straightforward and rapid method incorporate dose-averaged linear energy transfer (LET d )-based biological effect model into dose optimization algorithm for scanned protons; (2) apply novel beam delivery strategy with increased LET within target, thereby enhancing predicted using selected relative effectiveness (RBE) model.We first generated pristine Bragg curves in water their corresponding distributions 94 groups proton beams,...
A cortical plasticity after long-duration single side deafness (SSD) is advocated with neuroimaging evidence while little known about the short-duration SSDs. In this case-cohort study, we recruited unilateral sudden sensorineural hearing loss (SSNHL) patients and age-, gender-matched health controls (HC), followed by comprehensive analyses. The primary outcome measures were temporal alterations of varied dynamic functional network connectivity (dFNC) states, neurovascular coupling (NVC)...
Moderate-to-severe pain exists in the early postoperative period after laparoscopic renal surgery.We investigated analgesic effect of quadratus lumborum block (QLB) via two approaches patients undergoing nephrectomy.A randomised controlled trial.An academic tertiary care hospital Beijing, China.Ninety-six aged 18 to 70 years who were scheduled for elective radical or partial nephrectomy.Eligible allocated randomly a control group (no block), lateral QLB posterior group. Ultrasound-guided was...