Wen Qin

ORCID: 0000-0003-3380-1990
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Postharvest Quality and Shelf Life Management
  • RNA modifications and cancer
  • Advanced Chemical Sensor Technologies
  • Essential Oils and Antimicrobial Activity
  • Phytochemicals and Antioxidant Activities
  • MicroRNA in disease regulation
  • Plant Pathogens and Fungal Diseases
  • Meat and Animal Product Quality
  • Gut microbiota and health
  • Nanocomposite Films for Food Packaging
  • Plant Physiology and Cultivation Studies
  • Spectroscopy and Chemometric Analyses
  • Listeria monocytogenes in Food Safety
  • Cancer-related molecular mechanisms research
  • Heavy Metals in Plants
  • Edible Oils Quality and Analysis
  • Craniofacial Disorders and Treatments
  • Insect Pest Control Strategies
  • Ubiquitin and proteasome pathways
  • Immunotherapy and Immune Responses
  • Cervical Cancer and HPV Research
  • Circular RNAs in diseases
  • Head and Neck Anomalies
  • Pluripotent Stem Cells Research

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2023-2025

University of Electronic Science and Technology of China
2023-2025

Guangxi Medical University
2016-2025

Sichuan Agricultural University
2004-2025

Sichuan Cancer Hospital
2025

Air Force Medical University
2024

Shenzhen Maternity and Child Healthcare Hospital
2024

Second Affiliated Hospital of Nanjing Medical University
2024

Xiangyang Central Hospital
2022-2023

Xinqiao Hospital
2023

Abstract Tumor adaptation‐originated tumor tolerance that compensatory mechanisms (e.g., isocitrate dehydrogenase (IDH) mutation) jointly shape is the dominant obstacle of ROS therapy. Currently, targeting a single pathway fails to fundamentally reverse complex milieu and diminish adaptation. Herein, multichannel sonocatalysis amplifier engineered via one‐pot gas diffusion method attenuate IDH1‐mutated cholangiocarcinoma plasticity therapy, wherein triptolide IR780 are co‐loaded in...

10.1002/adfm.202303869 article EN Advanced Functional Materials 2023-07-11

The increasing world population and declining food supply demand innovation in the area of packaging, which explains current scientific focus on developing biodegradable edible packaging that has a minimum impact quality. Tea polyphenols (TPs) are explicitly isolated from tea leaves have been applied industry owing to their preservative properties. TPs used as active ingredients maintain overall appearance quality packaged food, thereby contributing safety consumer health. This review...

10.1016/j.lwt.2022.113845 article EN cc-by-nc-nd LWT 2022-08-07

Protein translation is an essential cellular process initiated by the association of a methionyl–tRNA with initiation factor eIF2. The Met-tRNA/eIF2 complex then associates small ribosomal subunit, other factors and mRNA, which together comprise translational complex. This regulated phosphorylation status α subunit eIF2 (eIF2α); phosphorylated eIF2α attenuates protein translation. Here, we report consanguineous family severe microcephaly, short stature, hypoplastic brainstem cord, delayed...

10.1093/hmg/ddv337 article EN cc-by-nc Human Molecular Genetics 2015-08-24

The aim of the present study was to investigate potential prognostic value members heat shock protein (HSP)90 family in non-small cell lung cancer (NSCLC) patients. mRNA expression profiles 1,926 NSCLC patients, which available from Kaplan-Meier plotter database, were included study. High HSP90AA1 significantly associated with a poorer rate overall survival (OS) for all patients [hazard ratio (HR), 1.21; 95% confidence interval (CI): 1.06-1.37; P=0.004], as well adenocarcinoma (ADE; HR, 1.3;...

10.3892/etm.2019.7228 article EN Experimental and Therapeutic Medicine 2019-01-31

The quality of blueberry fruit is easily altered after harvest. We investigated the regulatory mechanism heat-shock (postharvest treatment) and edible coating (preharvest on post-harvest physiological from perspective physiological, biochemical organoleptic characteristics. In our research, optimal TKL concentration appropriate range temperatures were first screened based actual application results, then a combination temperature with significant differences in preservation effects was...

10.3390/foods12040789 article EN cc-by Foods 2023-02-13

Effective treatment of patients with autism spectrum disorder (ASD) is still absent so far. Taurine exhibits therapeutic effects towards the autism-like behaviour in ASD model animals. Here, we determined mechanism taurine effect on hippocampal neurogenesis genetically inbred BTBR T + tf/J (BTBR) mice, a proposed ASD. In this mouse model, explored oral supplementation ASD-like behaviours an open field test, elevated plus maze, marble burying self-grooming and three-chamber test. The mice...

10.14712/fb2024070010045 article EN Folia Biologica 2024-01-01

Acute kidney injury (AKI) is quite common in the patients who frequently use anticancer drug cisplatin. microRNAs (miRNAs) are powerful tools modulating expression of key factors disease progression, but little known about roles miRNAs AKI. This study explored and function miR-449 cisplatin-induced AKI.Rat renal proximal tubular cell line NRK-52E was used for cisplatin treatment sponge transfection. MTT assay flow cytometry were performed to detect viability apoptosis different groups....

10.12659/msm.897187 article EN Medical Science Monitor 2016-03-12

As two main phototherapy means, photodynamic therapy (PDT) and photothermal (PTT) have different photon‐transition avenues decided by the aggregation state of photosensitizers (PSs), thus PDT or PTT efficiency can be regulated regulating PSs aggregation. A co‐assembly formulation consisting IR780 iodide pentafluorophenyl trifluoroacetate is constructed through intermolecular interactions, followed coating with hyaluronic acid. Initially, uniform distribution favors more reactive oxygen...

10.1002/sstr.202400574 article EN cc-by Small Structures 2025-01-14
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