A5024519667- Neurotransmitter Receptor Influence on Behavior
- Bacteriophages and microbial interactions
- Heavy Metal Exposure and Toxicity
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Computational Drug Discovery Methods
- Brucella: diagnosis, epidemiology, treatment
- Poxvirus research and outbreaks
- Epigenetics and DNA Methylation
- Plant Pathogens and Fungal Diseases
- Antibiotic Resistance in Bacteria
- vaccines and immunoinformatics approaches
- Burkholderia infections and melioidosis
- Bacterial Genetics and Biotechnology
- Retinoids in leukemia and cellular processes
- DNA and Nucleic Acid Chemistry
- Bioinformatics and Genomic Networks
- Galectins and Cancer Biology
- Genetics, Aging, and Longevity in Model Organisms
- Genomics and Phylogenetic Studies
- Fungal Infections and Studies
- Immunotherapy and Immune Responses
- Antifungal resistance and susceptibility
- Toxic Organic Pollutants Impact
- Sperm and Testicular Function
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
University of Arkansas for Medical Sciences
2024
National and Kapodistrian University of Athens
2024
Regione Toscana
2024
Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana
2024
Army Medical University
2020-2022
Xi'an Jiaotong University
2011
Inorganic arsenic (iAs) is a worldwide environmental pollutant which exerts complicated and various toxic effects in organisms. Increasingly epidemic studies have revealed the association between iAs exposure adult male reproductive impairment. Consistent with proposal for toxicity testing 21st century (TT21C), adverse outcome pathway (AOP) framework may help unravel iAs-caused molecular functional changes leading to impairment.Combining CTD's phenotype-disease inference data, iAs-phenotypes...
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Benzo[a]pyrene (B[a]P), a representative of polycyclic aromatic hydrocarbons (PAHs), is ubiquitously spread in the environment and showing deleterious impacts on male steroidogenesis, including testosterone synthesis disorder. However, precise mechanisms involved B[a]P-induced steroidogenesis perturbation remains obscure. In present study, we integrated vivo tests, transcriptome profiling, vitro assays, conjoint silico toxicological approaches to delineate detailed mechanisms. mouse models,...
Klebsiella pneumoniae is a common human commensal and opportunistic pathogen. In recent years, the clinical isolation resistance rates of K. have shown yearly increase, leading to special interest in mobile genetic elements. Prophages are representative class elements that can carry host-friendly genes, transfer horizontally between strains, coevolve with host's genome. this study, we identified 15,946 prophages from genomes 1437 fully assembled deposited NCBI database, 9755 on chromosomes...
Talaromyces (Penicillium) marneffei is an intracellular pathogenic fungus. Some strains of this fungus have been misidentified due to the similarity between and Penicillium. T. has mainly found afflict immunocompromised individuals, causing respiratory, skin, systemic mycosis. Mp1p a key virulence factor that can help evade clearance by normally functioning immune system. Understanding how novel functions arise intriguing question in many fields biology. two homologous domains (Mp1p-LBD1...
Background: Human male fertility shows a continuously decline tendency in recent decades. Over exposure to metal/metalloid elements has been proposed be associated with reproductive impairment. However, the hazard profile remained unclear general public low-level and combined metal exposure.Methods: Base on college-student population of MARHCS study Chongqing, China, 796 college students were recruited from June 2013 666 subjects followed up next year. At each phase, semen blood samples...