A5066339858- Radio Astronomy Observations and Technology
- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Microwave Engineering and Waveguides
- Superconducting and THz Device Technology
- Antenna Design and Optimization
- Management of metastatic bone disease
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Pulsars and Gravitational Waves Research
- Astrophysics and Cosmic Phenomena
- Galaxies: Formation, Evolution, Phenomena
- Prostate Cancer Diagnosis and Treatment
- Cosmology and Gravitation Theories
- Methane Hydrates and Related Phenomena
- Radiation Detection and Scintillator Technologies
- Atmospheric and Environmental Gas Dynamics
- Radiation Effects and Dosimetry
- Angiogenesis and VEGF in Cancer
- Gamma-ray bursts and supernovae
- Medical Imaging and Analysis
- Radio Frequency Integrated Circuit Design
- Lung Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
University of Toronto
2014-2022
Memorial Sloan Kettering Cancer Center
2019-2020
The University of Texas Southwestern Medical Center
2017-2020
Southwestern Medical Center
2017
Canadian Institute for Theoretical Astrophysics
2015
IBM (Canada)
2014
MW Canada (Canada)
2014
The Canadian Hydrogen Intensity Mapping Experiment (CHIME) is a drift scan radio telescope operating across the 400-800 MHz band. CHIME located at Dominion Radio Astrophysical Observatory near Penticton, BC Canada. instrument designed to map neutral hydrogen over redshift range 0.8 2.5 constrain expansion history of Universe. This goal drives design features instrument. consists four parallel cylindrical reflectors, oriented north-south, each 100 m $\times$ 20 and outfitted with 256 element...
A pathfinder version of CHIME (the Canadian Hydrogen Intensity Mapping Experiment) is currently being commissioned at the Dominion Radio Astrophysical Observatory (DRAO) in Penticton, BC. The instrument a hybrid cylindrical interferometer designed to measure large scale neutral hydrogen power spectrum across redshift range 0.8 2.5. will be used baryon acoustic oscillation (BAO) this poorly probed where dark energy becomes significant contributor evolution Universe. revives cylinder design...
Purpose To evaluate pix2pix and CycleGAN to assess the effects of multiple combination strategies on accuracy for patch‐based synthetic computed tomography (sCT) generation magnetic resonance (MR)‐only treatment planning in head neck (HN) cancer patients. Materials methods Twenty‐three deformably registered pairs CT mDixon FFE MR datasets from HN patients treated at our institution were retrospectively analyzed sCT via models. test overlapping patches estimations, we (a) trained models three...
The Canadian Hydrogen Intensity Mapping Experiment (CHIME) is a transit interferometer currently being built at the Dominion Radio Astrophysical Observatory (DRAO) in Penticton, BC, Canada. We will use CHIME to map neutral hydrogen frequency range 400 { 800MHz over half of sky, producing measurement baryon acoustic oscillations (BAO) redshifts between 0.8 2.5 probe dark energy. have deployed pathfinder version that yield constraints on BAO power spectrum and provide test-bed for our...
Inverse treatment planning in radiation therapy is formulated as optimization problems. The objective function and constraints consist of multiple terms designed for different clinical practical considerations. Weighting factors these are needed to define the problem. While a system can solve problem with given weights, adjusting weights high plan quality performed by human. weight tuning task labor intensive, time consuming, it critically affects final quality. An automatic weight-tuning...
We have developed FFT beamforming techniques for the CHIME radio telescope, to search and localize astrophysical signals from Fast Radio Bursts (FRBs) over a large instantaneous field-of-view (FOV) while maintaining full angular resolution of CHIME. implement hybrid pipeline in GPU correlator, synthesizing 256 FFT-formed beams North-South direction by four formed along East-West via exact phasing, tiling sky area ~250 square degrees. A zero-padding approximation is employed improve chromatic...
We present results from a new incoherent-beam Fast Radio Burst (FRB) search on the Canadian Hydrogen Intensity Mapping Experiment (CHIME) Pathfinder. Its large instantaneous field of view (FoV) and relative thermal insensitivity allow us to probe ultra-bright tail FRB distribution, test recent claim that this distribution's slope, $\alpha\equiv-\frac{\partial \log N}{\partial S}$, is quite small. A 256-input incoherent beamformer was deployed CHIME Pathfinder for purpose. If distribution...
High dose rate (HDR) brachytherapy treatment planning is conventionally performed manually and/or with aids of preplanned templates. In general, the standard care would be elevated by conducting an automated process to improve efficiency, eliminate human error, and reduce plan quality variations. Thus, our group developing AutoBrachy, HDR suite modules used augment a clinical system. This paper describes proof-of-concept module for vaginal cylinder that has been fully developed. After...
We present the design and implementation of a custom GPU-based compute cluster that provides correlation X-engine CHIME Pathfinder radio telescope. It is among largest such systems in operation, correlating 32,896 baselines (256 inputs) over 400MHz bandwidth. Making heavy use consumer-grade parts software stack, system was developed at small fraction cost comparable installations. Unlike existing GPU backends, this built around OpenCL kernels running on consumer-level AMD GPUs, taking...
The CHIME Pathfinder is a new interferometric radio telescope that uses hybrid FPGA/GPU FX correlator. GPU-based X-engine of this correlator processes over 819 Gb/s 4+4-bit complex astronomical data from N=256 inputs across 400MHz band. A software framework presented to manage real-time flow, which allows each 16 processing servers handle 51.2 data, plus 8 ancillary data. Each server receives in the form UDP packets an FPGA F-engine eight 10 GbE links, combines these into large (32MB-256MB)...
Interferometric radio telescopes often rely on computationally expensive O(N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) correlation calculations; fortunately these computations map well to massively parallel accelerators such as low-cost GPUs. This paper describes the OpenCL kernels developed for GPU based X-engine of a new hybrid FX correlator. Channelized data from F-engine is supplied GPUs 4-bit, offset-encoded real and...
A total of twenty paired CT and MR images were used in this study to investigate two conditional generative adversarial networks, Pix2Pix, Cycle GAN, for generating synthetic Headand Neck cancer cases. Ten the patient cases training included such common artifacts as dental implants; remaining ten testing a larger range image features commonly found clinical head neck These strong metal from implants, one case with implant, abnormal anatomy. The original deformably registered mDixon FFE...
The CHIME Pathfinder is a new interferometric radio telescope that uses hybrid FPGA/GPU FX correlator. GPU-based X-engine of this correlator processes over 819 Gb/s 4+4-bit complex astronomical data from N=256 inputs across 400 MHz band. A software framework presented to manage real-time flow, which allows each 16 processing servers handle 51.2 data, plus 8 ancillary data. Each server receives in the form UDP packets an FPGA F-engine eight 10 GbE links, combines these into large (32MB-256MB)...
Interferometric radio telescopes often rely on computationally expensive O(N^2) correlation calculations; fortunately these computations map well to massively parallel accelerators such as low-cost GPUs. This paper describes the OpenCL kernels developed for GPU based X-engine of a new hybrid FX correlator. Channelized data from F-engine is supplied GPUs 4-bit, offset-encoded real and imaginary integers. Because low bit width data, two values may be packed into 32-bit register, allowing...
Purpose:To investigate the radiation dose rate effect for pulsed lowdose-rate (PLDR) therapy using in vitro clonogenic analysis. Materials and Methods: Lung cell line A549 (Adenocarcinomic human alveolar basal epithelial cells) prostate cancer cells (PC3) were cultured Dulbecco's modified Eagle's medium supplemented with 10% fetal calf serum, penicillin (50 U/ml), streptomycin µg/ml) at 37°C under 95% humidity 5% CO2 atmosphere.All experiments used exponential growth phase by seeding ~200...
High dose-rate brachytherapy (HDRBT) is widely used for gynecological cancer treatment. Although commercial treatment planning systems (TPSs) have inverse optimization modules, it takes several iterations to adjust objectives achieve a satisfactory plan. Interactive plan-modification modules enable modifying the plan and visualizing results in real time, but they update plans based on simple geometrical or heuristic algorithms, which cannot ensure resulting optimality. This project develops...