- Orthopedic Surgery and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Bone fractures and treatments
- Elbow and Forearm Trauma Treatment
- Reconstructive Facial Surgery Techniques
- Developmental Biology and Gene Regulation
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Musculoskeletal synovial abnormalities and treatments
- Nerve Injury and Rehabilitation
- Orthopedic Infections and Treatments
- Congenital limb and hand anomalies
- Peripheral Nerve Disorders
- Tendon Structure and Treatment
- Periodontal Regeneration and Treatments
- Gastric Cancer Management and Outcomes
- Vascular Procedures and Complications
- Foot and Ankle Surgery
- Metastasis and carcinoma case studies
- Congenital heart defects research
- Gastrointestinal Tumor Research and Treatment
- Total Knee Arthroplasty Outcomes
- Shoulder and Clavicle Injuries
- Allergic Rhinitis and Sensitization
Nara City Hospital
2012-2024
The Japanese Society of Gastroenterological Surgery
2024
Tokyo Denki University
2013-2019
Jikei University School of Medicine
1999-2018
Jikei University Kashiwa hospital
2012-2018
Nara Medical University
2006-2017
Jichi Medical University
2007-2016
Handa City Hospital
2016
Katsushika Medical Center
2012-2015
Tochigi Medical Center
2010
Autologous mesenchymal stem cells (MSCs) cultured with beta-tricalcium phosphate (beta-TCP) ceramics and a free vascularized fibula were transplanted into three patients steroid-induced osteonecrosis of the femoral head. The average follow-up period was 34 months patient age at time surgery 28 years old. Fifteen milliliters bone marrow obtained from 4 weeks before surgery, used for in vitro proliferation MSCs. beta-TCP granules immersed MSC suspension further 2 weeks. Cultured MSCs/beta-TCP...
We performed a one-stage opening-wedge valgus osteotomy in nine patients to correct post-traumatic progressive varus deformity of the ankle. The site was stabilized with two, three, or four Kirschner wires plate and screws (in one patient). united within two months after operation eight at six patient who fifty-nine years old. average duration follow-up seven (range, thirteen months). Postoperatively, range motion ankle decreased remained unchanged three. However, none reported any...
It is well known that bone marrow contains mesenchymal stromal cells (MSCs), which can show osteoblastic differentiation when cultured in osteogenic medium containing ascorbic acid, beta-glycerophosphate and dexamethasone. The results the appearance of osteoblasts, together with formation matrix; thus, vitro (osteoblasts/bone matrix) could be fabricated by MSC culture. This type has already been used clinical cases involving orthopaedic problems. To improve therapeutic effect bone, we...
Abstract Five patients underwent mandibular reconstruction using the double barrel fibular graft from 1989 to 1994. Bony defects ranged 7 14 cm. In three patients, two skin flaps were taken with for composite reconstruction. order overcome main disadvantage of graft, i.e., small circumference bone, a harvested fibula was osteotomized into several portions, folded parallel lengths, and fixed along inferior border mandible alveolar ridge. The provided more than 4‐cm height without damaging...
From 1979 to 1990 we treated 20 patients with large bone defects or established nonunion of the femur by vascularised fibular grafts. There were 18 men and two women an average age at operation 36.6 years (16 69). Ten had infected nonunion, three post-traumatic a defect without infection, four after tumour resection, other lesions. The mean length grafts was 18.1 cm. Postoperative circulatory disturbances needed revision surgery in five patients, including problems monitoring flap, but not...
Treatment of congenital pseudarthrosis the tibia (CPT) remains a challenge. To clarify current situation in treatment, multicenter study was carried out to obtain information on results CPT treatment. The objective this propose appropriate treatment guidelines for CPT. Records 73 patients with who underwent surgical were collected from 32 hospitals. modality 26 Ilizarov technique, 25 free vascularized fibular graft, 7 combination two techniques, 6 intramedullary nailing bone grafting, 5...
From 1976 to 1989, 33 patients with osteomyelitis and infected nonunion of lower extremity bones were treated vascularized fibular grafts. There 30 males three females, the ages at operation ranged from 17 69 years. 24 tibial lesions nine femoral lesions. The graft was performed immediately after lesional debridement in eight patients, but 25 it done secondarily successful subsidence inflammation. mean interval between last grafting ten weeks. Thirty grafts survived. periods required obtain...
From 1988 to 1992, 17 patients were treated for a large bone defect or established nonunion of the pelvis lower extremities with twin-barrelled vascularized fibular grafts. There 13 men and four women whose average age at operation was 39 years (range, 13-73 years). The reconstructed site in two patients, femur 12, tibia two, ankle one. mean length 8.5 cm, harvested fibula 22 cm. Free grafts transferred 14 pedicle three patients. duration six hours 46 minutes 3.5-10.6 hours). Average blood...
The present study aimed to determine the indications for free vascularized fibular grafting treatment of osteonecrosis femoral head.Seventy-one hips (60 patients) were clinically followed a minimum 3 years. Average follow-up period was 7 Etiologies alcohol abuse in 31 hips, steroid use 27, idiopathic and trauma 6. Preoperative staging necrotic lesion done using Steinberg's classification system. outcomes determined Harris hip-scoring system, radiographically by determining progression,...
Seven patients with a giant-cell tumor involving the distal end of radius were treated en bloc resection and reconstruction free vascularized fibular graft. Two stage 2 disease Enneking's surgical staging grade Campanacci's radiographic grading system reconstructed an articular head Five 3 underwent wrist arthrodesis using shaft transfer. There was evidence bone union at host-graft junctions in all cases. No local recurrence seen any most recent follow-up examinations. six good one excellent...
Clinical applications of two free lateral leg perforator flaps are described: a soleus flap that is based on the musculocutaneous vessels from one three main arteries in proximal lower leg, and peroneal septocutaneous or direct skin artery distal middle thirds leg. The authors applied to 18 patients five with soft-tissue defects. recipient site was great toe 14 patients, hand fingers upper arm jaw patient each. largest 15 x 9 cm, 4 cm. Vascular pedicle lengths ranged 6.5 10 cm 6 flaps. All...
An experimental study of vascularized tibiofibula grafts in inbred rats was performed. Roentgenologic and histologic changes the grafted bone first seven postoperative weeks were especially investigated. After preliminary experiments on vascular anatomy lower limbs rats, tibiofibular with femoral artery vein utilized Fischer strain F-344 rats. The rate bony union graft group superior to that nonvascularized control groups. Fluorochrome-labeling studies at mid-diaphysis showed active...