A5082106288- Knee injuries and reconstruction techniques
- Neonatal Respiratory Health Research
- Total Knee Arthroplasty Outcomes
- Osteoarthritis Treatment and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Preterm Birth and Chorioamnionitis
- Sports injuries and prevention
- Infant Nutrition and Health
- Respiratory Support and Mechanisms
- Chronic Disease Management Strategies
- Lower Extremity Biomechanics and Pathologies
- Intestinal Malrotation and Obstruction Disorders
- Tendon Structure and Treatment
- Vascular Procedures and Complications
- Inflammatory mediators and NSAID effects
- Retinopathy of Prematurity Studies
- Neonatal and fetal brain pathology
- Neonatal and Maternal Infections
- Cardiovascular Conditions and Treatments
- Lymphatic Disorders and Treatments
- Neuroscience of respiration and sleep
- Cardiovascular Issues in Pregnancy
- Cardiac Health and Mental Health
- Analytical Methods in Pharmaceuticals
- Connective tissue disorders research
Kumamoto City Hospital
2016-2025
Tokyo Medical and Dental University Hospital
2017-2021
Doai Memorial Hospital
2021
Noguchi Hospital
2021
Tokyo Medical and Dental University
2018-2020
JA Toride Medical Center
2016
Kobe Children's Hospital
2012-2014
Boston Children's Hospital
2011-2012
Osteoarthritis (OA) is a common joint disease in aging societies, which accompanied by chronic inflammation and degeneration of the structure. Inflammation infrapatellar fat pad (IFP) synovial membrane (IFP surface) plays essential roles persistent pain development patients with OA. To identify point during inflammatory process critical for development, we performed time course histological analysis rat arthritis model.Wistar rats received single intra-articular injection monoiodoacetic acid...
The infrapatellar fat pad (IFP) contains nerve fiber endings and is considered to play an important role in the perception of knee pain. However, it unclear whether what degree prolonged pain influences nociceptive IFP. To answer this question, we established a novel rat model which inflammation restricted Rats received single intra-IFP injection monoiodoacetic acid (MIA) (0.2 mg/10 µL or 1.0 µL) left phosphate-buffered saline (10 right as control. Pain-avoidance behavior histological...
Abstract Background The aim of this study was to determine whether patterns increases in serum interleukin‐6 ( IL ‐6) and C ‐reactive protein CRP ) levels at birth were associated with the development white matter injury WMI preterm infants a fetal inflammatory response FIR ). Methods One hundred who born <32 weeks gestation had funisitis, as determined by histological evidence , studied. Infants divided into four groups according ‐6 birth, cut‐off values 200 pg/mL 0.4 mg/dL,...
Popliteal artery occlusion after total knee arthroplasty is rare (0.03-0.17%) but can lead to amputation if overlooked. We should carefully assess vascular patency by Doppler ultrasound and ankle brachial pressure index (ABPI) measurement before (TKA) operation.
Early postnatal hyperoxia is a major risk factor for retinopathy of prematurity (ROP) in extremely premature infants. To reduce the occurrence ROP, we adopted lower early oxygen saturation (SpO2 ) target range (85-92%) from April 2011. Lower SpO2 range, however, may lead to hypoxemia and an increase ductus arteriosus (DA) closure failure. The aim this study was therefore determine whether during stage, increases DA failure.Infants born at <28 weeks' gestation were enrolled study. Oxygen...
Abstract This open‐label, multicenter, prospective, randomized controlled trial aimed to determine the effectiveness of esflurbiprofen plaster (SFPP) and flurbiprofen tablets (FPTs) on knee osteoarthritis in patients scheduled for total arthroplasty by comparing transfer tissues fluids. Thirty‐eight were randomly assigned a 1:1 ratio receive SFPP or FPT. Both groups then divided into four subgroups, according whether they received final dose FPT at 2, 7, 12, 24 h before planned surgery. The...
ObjectivesTo compare the effects of anterior cruciate ligament (ACL) injuries and preoperative period on functional status in different sports using patient data from Multicenter Arthroscopic Knee Surgery (MAKS) study, a multicentre prospective cohort study patients who underwent ACL reconstructions meniscal surgeries conducted 2013.MethodsOf 1648 registered MAKS cohort, 826 unilateral primary reconstruction. These were divided into three groups based activity type: contact, fighting...
高齢者夫婦二人世帯に発症した大腿骨近位部骨折の自宅復帰について調査した。 地域連携パス開始後の2007年1月から2013年12月までに手術加療した65歳以上の夫婦二人世帯の大腿骨近位部骨折85例87関節を対象とした。 急性期病院または回復期病院から退院時の自宅復帰数（率），急性期，回復期病院の入院期間，受傷前と急性期または回復期病院退院時の移動能力を調査した。認知症の有無と年齢階層別について自宅退院数を調査した。 急性期病院から直接自宅復帰数は32例（36％）。回復期病院から自宅復帰数は35例（83％）。急性期病院から直接自宅復帰例での入院期間は平均31日（17～71日）。回復期病院から自宅復帰例での回復期病院での入院期間は平均61日（5～143日）。急性期病院から直接自宅復帰例での受傷前と退院時の移動能力は受傷前が独歩22例，杖5例，伝い歩き3例，つかまり立ち2例であったが，退院時は独歩3例，杖21例，伝い歩き5例，つかまり立ち1例，車椅子2例であった。...
胎児Loeys-Dietz症候群と臨床的に診断した症例を経験したので報告する．33歳の初妊初産婦．特記すべき既往歴，家族歴はなかった．妊娠26週1日に大動脈の弁直上の著明な拡張と弁逆流，上行・下行大動脈の拡張と下行大動脈の蛇行所見，肺動脈弁直上の著明な拡張と弁逆流を認めた．心嚢液貯留，全身の皮下浮腫，腹水貯留が出現し，妊娠31週3日に帝王切開分娩となった．胎児期には重症な動脈弁逆流と大動脈逆流を合併した胎児心不全と診断したが，Marfan類縁疾患との明確な診断には至らなかった．出生時体重2,262 g （＋3.11 S.D）の男児，身長は45.0 cm（＋1.91 S.D.），Apgar...