A5102995381- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Cancer Risks and Factors
- Gestational Diabetes Research and Management
- Immune Cell Function and Interaction
- Diabetes and associated disorders
- Infectious Encephalopathies and Encephalitis
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Folate and B Vitamins Research
- Neutropenia and Cancer Infections
- Retinal Diseases and Treatments
- Immune Response and Inflammation
- Head and Neck Cancer Studies
- Hematological disorders and diagnostics
- Ethics and Legal Issues in Pediatric Healthcare
- Parvovirus B19 Infection Studies
- Radioactivity and Radon Measurements
- Congenital Diaphragmatic Hernia Studies
- Birth, Development, and Health
- Arsenic contamination and mitigation
- Diabetes Management and Research
- Pancreatic function and diabetes
- T-cell and B-cell Immunology
- Autoimmune Neurological Disorders and Treatments
Primary Children's Hospital
2024
University of Utah
2024
Jackson Memorial Hospital
2022
Sylvester Comprehensive Cancer Center
2021-2022
University of Miami
2021-2022
Jackson Health System
2021
University of Minnesota
2019-2020
Jadavpur University
2012-2017
University of Maryland, Baltimore
2016
University of California, San Francisco
2008-2009
Regulatory T-cells (Tregs) have catalyzed the field of immune regulation. However, translating Treg-based therapies from animal models autoimmunity to human clinical trials requires robust methods for isolation and expansion these cells-a need forming basis studies.Tregs recent-onset type 1 diabetic patients healthy control subjects were isolated by fluorescence-activated cell sorting compared their capacity expand in vitro response anti-CD3-anti-CD28-coated microbeads IL-2. Expanded cells...
Abstract Background Obesity is a risk factor for many adulthood cancers, but its role in childhood, adolescent, and young adult (AYA) cancer unknown. Childhood AYA acute lymphoblastic leukemia (ALL) incidence obesity prevalence have shown concurrent increases. We sought to identify whether may be childhood ALL. Methods Characteristics from individuals with ALL, aged 2‐30 years, diagnosed 2004‐2017 treated on Children's Oncology Group (COG) protocols available pre‐treatment anthropometric...
The outcome of different studies on the role Zn & Mo in esophageal cancer (EC) is conflicting. Here, levels those elements hair as well food grain two ethnic populations across continents have been studied to explore their EC. Two are taken from (i) Eastern Cape, South Africa (RSA), an area very high incidence EC and (ii) West Bengal, India, low that disease. Each population divided into groups: case control (n=30for all groups). Hair samples groups RSA India analyzed for content. This study...
A rare lymphoproliferative disorder involving thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), renal dysfunction and organomegaly (O), called TAFRO syndrome, was first reported in 2010. Considered a variant of idiopathic multicentric Castleman's disease, the recent discovery rarity this syndrome pose challenges to diagnosis management. Herein, we review three pediatric cases, including an infant, that illustrate heterogeneity syndrome. Despite differences presentation...
Abstract Background Subsequent short‐latency leukemias are well‐described among survivors of childhood cancer. However, late (5–14.9 years from diagnosis, LL) and very (≥15 VLL) subsequent have not been well studied. We assessed risk factors, prevalence, outcomes for LL VLL in the Childhood Cancer Survivor Study cohort. Methods leukemias, 25,656 five‐year survivors, were self‐reported confirmed by pathology review. Standardized incidence ratios (SIR) cumulative incidences calculated,...
Retinoblastoma (RB) is the most common intraocular pediatric malignancy. Advancements in intra-arterial chemotherapy (IAC) for treatment of RB have resulted dramatic improvement eye salvage rates. Data regarding IAC outcomes and associated hematologic toxicities are limited. The objective this retrospective study was to analyze baseline characteristics, efficacy, complications with children at a single international referral institution. Ninety-five sessions were performed 28 patients. Mean...
Introduction: Increases in the incidence of both obesity (a risk factor for many adulthood cancers) and acute lymphoblastic leukemia (ALL) childhood have been observed over past three decades, thus we sought to identify whether may be an unrecognized ALL.Methods: Demographics, anthropometrics disease characteristics from children young adults (aged 1-30 years) diagnosed with ALL between 2004-2017 treated on Children's Oncology Group (COG) frontline treatment protocols available pre-treatment...
Abstract Introduction: Increases in the incidence of both obesity (a risk factor for many adulthood cancers) and acute lymphoblastic leukemia (ALL) childhood have been observed over past three decades, thus we sought to identify whether may be an unrecognized ALL. Methods: Demographics, anthropometrics disease characteristics from children young adults (aged 1-30 years) diagnosed with ALL between 2004-2017 treated on Children’s Oncology Group (COG) frontline treatment protocols available...
10551 Background: Lung cancer has been reported as a subsequent neoplasm (SN) in childhood survivors. We aimed to assess the prevalence of and risk factors for lung CCSS. Methods: Among 25,654 five-year survivors participating CCSS, was self-reported then confirmed by pathologic record review. Cancer treatment exposures were evaluated including chemotherapy chest radiation field size (none, small, large) dose group (0-10 Gy, 10-30 30-40 > 40 Gy). Standardized incidence ratios (SIR)...