A5024844208- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Family Support in Illness
- Adolescent and Pediatric Healthcare
- Neuroblastoma Research and Treatments
- Catalysis and Oxidation Reactions
- Neutropenia and Cancer Infections
- Palliative Care and End-of-Life Issues
- Electrocatalysts for Energy Conversion
- CO2 Reduction Techniques and Catalysts
- Food Security and Health in Diverse Populations
- Acute Myeloid Leukemia Research
- Innovations in Medical Education
- Economic and Financial Impacts of Cancer
- Racial and Ethnic Identity Research
- Empathy and Medical Education
- Neonatal Health and Biochemistry
- Glioma Diagnosis and Treatment
- Cancer-related cognitive impairment studies
- COVID-19 epidemiological studies
- Health disparities and outcomes
- COVID-19 and healthcare impacts
- Fuel Cells and Related Materials
- Lung Cancer Research Studies
- Perfectionism, Procrastination, Anxiety Studies
Children's Hospital of Philadelphia
2021-2025
Massachusetts Institute of Technology
2020-2024
University of Pennsylvania
2023-2024
Hong Kong Polytechnic University
2023
Boston Children's Hospital
2017-2022
Boston Medical Center
2017-2022
Massachusetts General Hospital
2022
Harvard University
2022
Boston University
2022
Boston Children's Museum
2018-2021
The medical community recognizes the importance of confronting structural racism and implicit bias to address health inequities. Several curricula aimed at teaching trainees about these issues are described in literature. However, few exist that engage faculty members as learners rather than teachers topics or target interdisciplinary audiences.We developed a longitudinal case conference curriculum called Health Equity Rounds (HER) discuss impact on patient care. engaged participants across...
Abstract The direct partial oxidation of methane to methanol promises an energy‐efficient and environmental‐friendly utilization natural gas. Unfortunately, current technologies confront a grand challenge in catalysis, particularly the context distributed sources. Research has been focused on design homogenous heterogenous catalysts improve activation under thermal electrochemical conditions. However, intrinsic relationship between systems not exploited yet. This review intends bridge...
Catalysts based on Fe-Nx sites have promising catalytic activity for the oxygen reduction reaction (ORR). While homogeneous Fe-N4 macrocycle molecules and heterogeneous Fe-N-doped carbon materials been studied extensively, systematic strategies to tune ORR energetics activities of Fe-Nx-based remain elusive. Herein, we show that carbon-supported Fe-phthalocyanine-based catalysts (FePPc/C) can be functionalized by electron-withdrawing/donating substituents electronic structures Fe center...
Background Over 70% of childhood cancer survivors develop late complications from therapy, many which can be mitigated by physical activity. Survivors engage in exercise at similar or lower rates than their sedentary healthy peers. We piloted a novel home-based intervention with motivational activity tracker. evaluated (i) feasibility, (ii) impact on levels and fitness, (iii) barriers, preferences, beliefs regarding Methods Childhood currently 15 years older not meeting the Centers for...
BACKGROUND Neuroblastoma survivors may be at elevated risk for psychological impairments because of their young age diagnosis and neurotoxic treatment, but this is not well described. METHODS A total 859 ≥5‐year neuroblastoma younger than 18 years (diagnosed in 1970‐1999), who had a median 0.8 (range: 0.0‐7.3 years) follow‐up 13.3 8.0‐17.9 years), were compared with 872 siblings childhood cancer the parent‐reported Behavior Problem Index (BPI) functioning. Age‐ sex‐adjusted multivariate...
Abstract Background Poverty is associated with inferior psychosocial outcomes, higher rates of relapse, and decreased overall survival in children cancer. Despite this, there are few evidence‐based, poverty‐targeted interventions none specific to pediatric oncology. To address this gap, we developed refined the Pediatric Cancer Resource Equity (PediCARE) intervention, a household material hardship (HMH) targeted intervention providing transportation groceries oncology families. Methods This...
BACKGROUND Children with average‐risk acute lymphoblastic leukemia (AR‐ALL) face many challenges that can adversely affect their quality of life (QOL). However, to the authors' knowledge, patterns and predictors QOL impairment during therapy have not been well characterized date. METHODS Patients AR‐ALL who were enrolled on Children's Oncology Group AALL0932 trial offered participation in this prospective cohort study if they aged ≥4 years at time diagnosis had an English‐speaking parent. At...
Non-Hispanic Black populations have suffered much greater per capita COVID-19 mortality than White populations. Previous work has shown that rates of and converged over time. Understanding disparities time is complicated by geographic changes in prevalence, some prior research claimed regional shifts prevalence may explain the convergence.Using county-level data stratified race, we investigate trajectory from June 2020-January 2021. We use a county fixed-effects model to estimate within...
PURPOSE Cancer-related financial hardship is associated with poor quality of life, risk household material hardship, and psychological distress for families affected by pediatric cancer. Current processes on screening navigation across the National Cancer Institute Community Oncology Research Program (NCORP) network remain unknown. METHODS Financial services among NCORP practices were assessed using two survey items from 2022 Landscape Assessment Survey. Practices answering yes to providing...
10028 Background: Chimeric antigen receptor T cell (CAR) therapy has revolutionized the treatment of relapsed/refractory pediatric B malignancies. However, financial toxicity (FT) experienced by families is unknown despite likely high burden imposed clinic visits, hospital admissions, and potential travel/relocation to referral centers. We present first report FT among children receiving CAR including prevalence, trajectory, impact on outcomes. Methods: This a prospective cohort analysis...
10055 Background: Adult survivors of childhood cancer are at high risk for financial hardship due to the cumulative lifetime costs cancer-directed therapy and chronic health conditions. Whether neurocognitive impairment increases is unknown. Methods: Childhood (≥ 5-year survivors, diagnosed < 21 years age between 1970-1999) enrolled in CCSS completed a validated self-report Neurocognitive Questionnaire (NCQ) 2014 subsequent survey (age ≥ 26 completion) 3 later. The NCQ measured four...
Based on the strong link between poverty and child health outcomes, both American Academy of Pediatrics (AAP) national pediatric oncology associations have advocated for routine clinical screening. Systematic implementation this recommendation in is not yet standard, feasibility data are needed. We report screening a referral center baseline characteristics population.From 2013 to 2017, 448 families with newly diagnosed cancer at Dana-Farber/Boston Children's Cancer Blood Disorders Center...
Abstract Social determinants of health (SDoH) are associated with stark disparities in cancer outcomes, but systematic SDoH data collection is virtually absent from oncology clinical trials. Trial‐based essential to ensure representation marginalized populations, contextualize outcome disparities, and identify health‐equity intervention opportunities. We report the feasibility a pediatric multicenter therapeutic trial‐embedded investigation. Among 448 trial participants, 392 (87.5%) opted‐in...
Modern therapeutic advances in high-risk neuroblastoma have improved overall survival (OS), but it is unclear whether these gains been equitable. This study examined the relationship between socioeconomic status (SES) and (OS) children with SES-associated disparities changed over time.In this population-based cohort study, <18 years diagnosed (diagnosis at age ≥12 months metastatic disease) from 1991 to 2015 were identified through National Cancer Institute's Surveillance, Epidemiology, End...
Examine the influence of household income on health-related quality life (HRQOL) among children with newly diagnosed acute myeloid leukemia (AML). Secondary analysis data prospectively collected from pediatric patients receiving treatment for AML at 14 hospitals across United States. Household was self-reported a demographic survey. The examined mediators included acuity presentation and toxicity. Caregiver proxy reported assessment patient HRQOL Peds QL 4.0 Children (n = 131) caregivers...
The crucial role of electrolyte cations in CO2 electroreduction has received intensive attention. One prevailing theory is that through electrostatic interactions or direct coordination, larger such as Cs+ can better stabilize the key intermediate species for CO and multicarbon (C2+) product generation, example, on silver copper, respectively. Herein, we show smaller, more acidic alkali metal greatly enhance CO2-to-methanol conversion kinetics (Li+ > Na+ K+ Cs+) an immobilized molecular...