- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Salmonella and Campylobacter epidemiology
- Escherichia coli research studies
- Aquaculture disease management and microbiota
- Antibiotic Resistance in Bacteria
- Probiotics and Fermented Foods
- Urinary Tract Infections Management
- Essential Oils and Antimicrobial Activity
- Bacteriophages and microbial interactions
- Legionella and Acanthamoeba research
- Listeria monocytogenes in Food Safety
- Protein purification and stability
- Cystic Fibrosis Research Advances
- Vitamin D Research Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Folate and B Vitamins Research
- Nuclear Receptors and Signaling
- Nanoparticles: synthesis and applications
- Genomics and Rare Diseases
- Viral gastroenteritis research and epidemiology
- Pharmacological Effects of Natural Compounds
- Gold and Silver Nanoparticles Synthesis and Applications
- Nephrotoxicity and Medicinal Plants
- Heat shock proteins research
Taif University
2019-2022
University of Monastir
2011-2021
Institut Supérieur de Biotechnologie de Sfax
2020
Office of Livestock and Pasture
2008-2015
Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement
2007-2012
Pharmac
2012
Urinary tract infections (UTIs), caused by Escherichia coli 80% to 85% of the time, are one most important causes morbidity and health care spending affecting persons all ages. These lead many difficult problems, especially increasing resistance antibiotic drugs. Bacterial biofilms play an role in UTIs, responsible for persistent leading recurrences relapses. In this study, we have investigated antibacterial activity five medicinal plant essential oils against UTIs E. using disc diffusion...
Methicillin-resistant Staphylococcus aureus is a major human pathogen that poses high risk to patients due the development of biofilm. Biofilms, are complex biological systems difficult treat by conventional antibiotic therapy, which contributes >80% humans infections. In this report, we examined antibacterial activity Origanum majorana, Rosmarinus officinalis, and Thymus zygis medicinal plant essential oils against MRSA clinical isolates using disc diffusion MIC methods. Moreover,...
Klebsiella pneumoniae is an opportunistic pathogen responsible for a significant proportion of nosocomial and community-acquired infections. Genotypic variation in K. populations major barrier to control public health risk associated with pathogen. In this work, thirty were recovered from hospital tested their resistance antibiotics. Genetic variability the isolates was performed using PCR based on genes coding porins efflux pumps, (GTG)5 BOX repetitive sequences. showed heterogenicity...
Adhesion has been regarded as one of the basic features probiotics. The aim this study was to investigate influence acid stress on functional properties, such hydrophobicity, adhesion HeLa cells, and composition membrane fatty acids, Lactobacillus probiotics strains. Two strains casei were used. polystyrene, epithelial cells adhesion, acids analysis evaluated. Our results showed that properties hydrophobicity stressed significantly changed with different pH values. However, we found caused a...
Salmonella is an international foodborne pathogen widely disseminated in seawater that regularly causes large outbreaks of food poisoning. In this study, we have investigated the effect starvation on ability enterica serovar Typhimurium cells to adhere polystyrene microplate and Hep2 microcosms after incubation for 3 years. Cell surface hydrophobicity was evaluated. Effect stress fatty acids composition also established. Our results showed seawater, starved decreased significantly. However,...
Gold nanoparticles have gained interest in biomedical sciences the areas of nano-diagnostics, bio-labeling, drug delivery, and bacterial infection. In this study, we examined, for first time, antibacterial antibiofilm properties plasmonic gold nanoprisms against human pathogenic bacteria using MIC crystal violet. addition, expression level GroEL/GroES heat shock proteins was also investigated by western blot. were characterized TEM EDX, which showed equilateral triangular prisms with an...
The foodborne pathogen Salmonella enterica serovar Typhimurium was subjected to starvation in seawater microcosms for three years study modifications its outer membrane and extracellular protein profiles. After incubation, proteins profiles of stressed bacteria were found be altered when analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). These shown the appearance bands, as well level expression certain proteins. levels of sopE2, invA, sipA and sopBvirulence...
-2 ) to evaluate alterations in their virulence genes expression levels. Firstly, we searched for the presence of eight Vibrio cholerae genes, toxR, toxS, toxRS, ctxA, zot, ace, toxT, and pathogenicity island (VPI), genome investigated strains. The toxR toxS UVC-irradiated bacteria, studied by reverse transcriptase polymerase chain reaction, was found be altered. These variations were manifested an increase or a decrease level tested genes. Further, mRNA quantities VPI ace remained stable...
<b>Background and Objective:</b> Urinary tract infections believe to be one of the main acquainted by <i>Escherichia coli</i> in hospitals with an excessive incidence illness. This study aimed analyze antibiotic resistance profile molecular characteristics <i>E. isolates recovered from patients urinary infection at different Taif Governorate, Saudi Arabia. <b>Materials Methods:</b> Out 143 collected for 11 months, February-December 2019, 24 were...
Major depression disorder (MDD) is a common condition and syndromic sickness with devastating psychological, social, economic effects. In general, it widespread problem, the prevalence of MDD varies by country. The genetic contribution to estimated be around 35%. This study was done explore association between 5-methyl tetrahydrofolate reductase (5-MTHFR) integrin β3 subunit (ITGB3) genes polymorphism for development major depressive disorder. current comprised thirty patients, ranging in...