A5056896340- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- Analytical Chemistry and Chromatography
- Phytochemistry and Biological Activities
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Studies
- Chromatography in Natural Products
- Rheumatoid Arthritis Research and Therapies
- Corneal surgery and disorders
- Drug Transport and Resistance Mechanisms
- Gold and Silver Nanoparticles Synthesis and Applications
- Analytical Methods in Pharmaceuticals
- Flavonoids in Medical Research
- Natural product bioactivities and synthesis
- Nephrotoxicity and Medicinal Plants
- Medical Research and Treatments
- Healthcare and Venom Research
- Phytoestrogen effects and research
- Analytical chemistry methods development
- Biosensors and Analytical Detection
- Glaucoma and retinal disorders
- Advanced biosensing and bioanalysis techniques
- Cardiovascular Health and Risk Factors
- Plant-based Medicinal Research
- Corneal Surgery and Treatments
Capital Medical University
2011-2025
Beijing Anzhen Hospital
2020-2025
Jiangsu University
2021-2025
Beijing Friendship Hospital
2025
Nanjing Forestry University
2025
Third Affiliated Hospital of Sun Yat-sen University
2024
University of South China
2022-2024
Shandong Jianzhu University
2010-2024
Sun Yat-sen University
2020-2024
Shenzhen Technology University
2024
β-Elemene, a compound found in an herb used traditional Chinese medicine, has shown promising anti-cancer effects against broad spectrum of tumors. The mechanism by which β-elemene kills cells remains unclear. aim the present study is to investigate anti-tumor effect on human gastric cancer and molecular involved. β-Elemene inhibited viability MGC803 SGC7901 dose-dependent manner. suppression cell was due induction apoptosis. A robust autophagy observed treated with β-elemene; it...
A portable kit was demonstrated for rapid and reliable surface-enhanced Raman scattering (SERS) detection of drugs in human urine. This contains two sealed reagent tubes, a packet standardized SERS substrates, mini device. 3 min pretreatment separating amphetamines from urine developed with an extraction rate >80% examined by ultraperformance liquid chromatography (UPLC). Simultaneously, highly reproducible two-dimensional (2D) gold nanorod (GNR) arrays were assembled the use...
To the Editor: motivate health promotion by prevention of modifiable risk factors and further reduce burden cardiovascular disease (CVD), American Heart Association (AHA) recently updated modified Life's Simple 7 (LS7) (CVH) metrics to Essential 8 (LE8).[1] A recent study conducted in China other countries reported that lower LE8 score was associated with a higher atherosclerotic CVD incidence death.[2] However, whether CVH has different effects on acute coronary heart (CHD) stroke, more...
To date, our understanding of the global aortic aneurysm (AA) burden distribution is very limited.To assess a full view AA and attributable risk factors from 1990 to 2017.We extracted data deaths, disability-adjusted life years (DALYs), their corresponding age-standardized rates (ASRs), in general by age/sex 2017 Global Burden Disease (GBD) study. The current its changing trend were separately showed. spatial divergence was discussed four levels: global, five social-demographic index...
The objectives of this study are to characterize methamphetamine (MA) usage patterns during pregnancy, examine whether MA use associated with sociodemographic characteristics and prenatal care, test the hypothesis that persistent or increasing pregnancy is greater other illicit drugs. sample consisted 191 MA-using mothers who participated in a large-scale multi-site exposure. Patterns substance were assessed by maternal self-report via Substance Use Inventory (SUI), which included detailed...
Abstract: Icariin and icariside II (ICA II), 2 active components isolated from herba epimedii, have a closely structural relationship. There is evidence that icariin may be useful in the treatment of erectile dysfunction (ED); however, study on therapeutic efficacy ICA ED currently scant. We investigated effects improving function rats with streptozocin‐induced diabetes. Fifty 8‐week‐old Sprague‐Dawley were randomly distributed into normal control diabetic groups. Diabetes was induced by...
Abstract Disseminated Cryptococcosis infection typically occurs in immunocompromised patients, often manifested as pneumonia or meningoencephalitis. Cases with involvement of either prostate adrenal glands are less frequent. We describe a case an 62-year-old man new-found Idiopathic CD4 + T lymphocytopenia who presented urinary irritation symptoms followed by headache. The patient was finally diagnosed disseminated cryptococcosis prostate, gland the help combining histopathology...
The aims of this study are to characterize the biological disease-modifying antirheumatic drug (bDMARD) usage patterns in real-life and examine remission rate rheumatoid arthritis (RA) patients receiving bDMARDs routine clinical practice China. Consenting RA (≥18 years) from 15 teaching hospitals marketed were included. In total, 802 (81.3 % women, 49.0 ± 13.9 included; 89.5 a combination conventional synthetic DMARDs (csDMARDS), whereas 10.5 bDMARD monotherapy. Etanercept (including Enbrel®...
A basil-seed-based surface enhanced Raman scattering (SERS) sensor has been incorporated with a transfer pipet via plastic chamber to create an integrated portable device, in which the is used for flow injection. small amount of liquid sample loaded dry SERS using pipet. The basil-seed can store like sponge so that plasmonic silver nanoparticles deposited on keep intimate contact containing analyte, enhances sensitivity device. excessive then ejected out box by pipet, leaving substrate...
The aim of this study was to develop licochalcone A-loaded self-microemulsifying drug delivery system (LCA-SMEDDS) improve bioavailability and anti-hyperuricemic activity hydrophobic natural compound A (LCA). prepared LCA-SMEDDS characterised by transmission electron microscopy analysis, particle size, polymer dispersity index (PDI), zeta potential, stability tests in vitro release analysis. free LCA were orally administered Sprague-Dawley rats investigate respective bioavailability....
The overly simplistic geometric and electronic structures of single‐atom catalysts have become a significant bottleneck in the field sensing, impeding both design highly efficient electrochemical sensors establishment structure‐activity relationships. To address these challenges, we present novel strategy to boost sensing performance by precisely tuning single‐atomic interdistance (SAD) correlated (c‐SACs). A series Ru‐based c‐SACs (Rud=6.2 Å, Rud=7.0 Rud=9.3 Å) are synthesized with...
The present study focused on the characteristics of vaginal microbiomes in prepubertal girls with and without vulvovaginitis. We collected 24 samples 16 fecal from 10 aged 3-9 years vulvovaginitis healthy same age. were divided into three groups: swabs controls (HF), (HVS), (VVS). Sequencing V3-V4 region 16S rDNA gene was performed NovaSeq PE250 platform to reveal microbial community structure vulvovaginitis-associated microbiota. intestinal children also analyzed for comparison. This...
Aim: Methotrexate (Mtx) is prescribed to reduce pain and inflammation in arthritis patients; however, improved repair mobility of joints still are the major concerns. Magnesium oil (MO) improves joint repair; therefore, MO-assisted transdermal delivery Mtx was aimed.Methods: MO integrated nanoemulsion (Mtx-MONE) prepared with uniform size (175 ± 35.4 nm), pH (6.15 0.3) near skin pH, high entrapment efficiency (65 8.6%). Mtx-MONE transformed nanogel (Mtx-MONEG) semisolid consistency (43,408...
Objectives: Osteoporosis is widely regarded as a typical aged-related disease caused by impaired bone remodeling. This research was designed to explore the protective effects of electroacupuncture (EA) on senile osteoporosis in rat model and investigate underlying mechanisms. Methods: Three-month-old rats were randomly selected youth group, 24-month-old assigned elderly EA groups. Rats group received 30 min at bilateral SP10, ST36, K13 GB34 daily, 5 days week for 8 weeks. Bone mineral...