A5100330048- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Scoliosis diagnosis and treatment
- HER2/EGFR in Cancer Research
- Diversity and Career in Medicine
- Advanced MRI Techniques and Applications
- Breast Cancer Treatment Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer Treatment and Pharmacology
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Cardiovascular Health and Disease Prevention
- Receptor Mechanisms and Signaling
- Artificial Intelligence in Healthcare and Education
- Plant Pathogens and Fungal Diseases
- Global Health Workforce Issues
- Renin-Angiotensin System Studies
- Anatomy and Medical Technology
- Cardiovascular Issues in Pregnancy
- Coronary Interventions and Diagnostics
- Air Quality and Health Impacts
- Advanced X-ray and CT Imaging
Shanghai Jiao Tong University
2025
Ruijin Hospital
2025
Deyang Stomatological Hospital
2023-2025
Tianjin Medical University Cancer Institute and Hospital
2025
Air Force Medical University
2025
Heilongjiang Provincial Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2002-2024
Chongqing University
2024
Second Xiangya Hospital of Central South University
2024
Central South University
2019-2024
Abstract Aims Increased attenuation of pericoronary adipose tissue (PCAT) around the proximal right coronary artery (RCA) from computed tomography angiography (CTA) has been shown to be associated with inflammation and improved prediction cardiac death over plaque features. Our aim was investigate whether PCAT CT is related progression burden. Methods results We analysed CTA studies 111 stable patients (age 59.2 ± 9.8 years, 77% male) who underwent sequential (3.4 1.6 years between scans)...
Epicardial adipose tissue (EAT) is a visceral fat deposit related to coronary artery disease. Fully automated quantification of EAT volume in clinical routine could be timesaving and reliable tool for cardiovascular risk assessment. We propose new fully deep learning framework thoracic (TAT) from non-contrast calcium computed tomography (CT) scans. The first multi-task convolutional neural network (ConvNet) used determine heart limits perform segmentation tissues. second ConvNet, combined...
Importance Racial and sex disparities are prevalent in surgical trainees. Although retrospective studies on resident attrition have been conducted for individual specialties, this study analyzes racial differences among all subspecialties over an 18-year period. Objective To evaluate the specialties Design, Setting, Participants This was a large, cross-sectional, database that analyzed program-reported censuses (program information, demographics, status) obtained by Association of American...
There were large outbreaks of hand, foot, and mouth disease in both 2008 2009 China.Using the national surveillance data since 2 May 2008, we summarized epidemiologic characteristics recent outbreaks. Using a susceptible-infectious-recovered transmission model, evaluated transmissibility potential risk factors.Children ages 1.0 to 2.9 years most susceptible (odds ratios [OR] >2.3 as compared with other age-groups). Infant cases had highest incidences severe (ORs >1.4) death >2.4), well...
Epicardial adipose tissue (EAT) volume (cm3) and attenuation (Hounsfield units) may predict major adverse cardiovascular events (MACE). We aimed to evaluate the prognostic value of fully automated deep learning-based EAT measurements quantified from noncontrast cardiac computed tomography.Our study included 2068 asymptomatic subjects (56±9 years, 59% male) EISNER trial (Early Identification Subclinical Atherosclerosis by Noninvasive Imaging Research) with long-term follow-up after coronary...
Abstract Aims Our aim was to evaluate the performance of machine learning (ML), integrating clinical parameters with coronary artery calcium (CAC), and automated epicardial adipose tissue (EAT) quantification, for prediction long-term risk myocardial infarction (MI) cardiac death in asymptomatic subjects. Methods results study included 1912 subjects [1117 (58.4%) male, age: 55.8 ± 9.1 years] from prospective EISNER trial follow-up after CAC scoring. EAT volume density were quantified using a...
To evaluate the performance of deep learning for robust and fully automated quantification epicardial adipose tissue (EAT) from multicenter cardiac CT data.In this study, a convolutional neural network approach was trained to quantify EAT on non-contrast material-enhanced calcium-scoring scans multiple cohorts, scanners, protocols (n = 850). Deep compared with three expert readers interobserver variability in subset 141 scans. The algorithm incorporated into research software. Automated...
OBJECTIVESThis study aimed to evaluate the validity of risk assessment model (RAM) Caprini and Padua in identifying venous thromboembolism (VTE) among hospitalized medical patients.
We sought to evaluate the association of metabolic syndrome (MetS) and computed tomography (CT)-derived cardiometabolic biomarkers (non-alcoholic fatty liver disease [NAFLD] epicardial adipose tissue [EAT] measures) with long-term risk major adverse cardiovascular events (MACE) in asymptomatic individuals.This was a post-hoc analysis prospective EISNER (Early-Identification Subclinical Atherosclerosis by Noninvasive Imaging Research) study participants who underwent baseline coronary artery...
Abstract A lot of evidence indicates that cardiac fibroblasts are essential for maintaining the structure and function heart. The present study examined whether TGFBR3 (transforming growth factor type III receptor, also known as betaglycan) could prevent hypoxia‐induced injury in neonatal mice fibroblasts, if so, its possible molecular targets. MTT, electron microscopy TUNEL assay were used to identify cell viability apoptosis fibroblasts. Results showed hypoxia 24 h markedly reduce by 49.8...
Background: Coronary computed tomography angiography (CTA) allows quantification of stenosis. However, such quantitative analysis is not part clinical routine. We evaluated the feasibility utilizing deep learning for quantifying coronary artery disease from CTA. Methods: A total 716 diseased segments in 156 patients (66 ± 10 years) who underwent CTA were analyzed. Minimal luminal area (MLA), percent diameter stenosis (DS), and contrast density difference (CDD) measured using...
Growing rods (GRs) pose a higher risk of kyphosis gain while improving coronal deformity with intermittent distractions in early-onset scoliosis (EOS), but turn, increased may also affect GR correction outcomes. However, there is paucity data regarding the effect GRs on sagittal spinal profiles hyperkyphotic EOS. Thus, we aim to demonstrate how EOS responds treatment.Forty patients treated for were included and categorized into normal (N) group [20 degrees≤thoracic (TK)≤50 degrees] or...
Systematic investigations assessing the clinical impact of human parechovirus (HPeV) disease are sparse. Noninvasive stool samples may be useful for targeted hospital-based surveillance.In context a quality management program, all hospitalized children fulfilling predefined case criteria central nervous system (CNS) infection/inflammation underwent standardized neurologic examinations. Stool were collected HPeV and enterovirus (EV) polymerase chain reaction molecular typing at National...
Study Design. A retrospective study. Objective. To evaluate radiographic and cosmetic outcomes after posterior-only cervicothoracic hemivertebra resection instrumentation. Summary of Background Data. Cervicothoracic is a rare congenital deformity. It locates between the mobile cervical spine fixed thoracic spine, leading to rapid curve progression, shoulder imbalance, torticollis, facial asymmetry. Methods. This study reviewed consecutive series 18 patients with hemivertebra. All received...
Aims The value of core decompression (CD) in the treatment osteonecrosis femoral head (ONFH) remains controversial. We conducted a systematic review and meta-analysis to evaluate whether CD combined with other treatments could improve clinical radiological outcomes ONFH patients compared alone. Methods searched PubMed, Embase, Web Science, Cochrane Library databases until June 2020. All randomized controlled trials (RCTs) (CCTs) comparing alone measures (CD + cell therapy, bone grafting,...
Background Prognostic nutritional index (PNI) has recently been identified as a novel marker of status. However, existing evidences on the association between PNI and risk lower extremity deep venous thrombosis (LEDVT) are limited conflicting. Objective To determine LEDVT, further evaluate its diagnostic value. Methods Over 10-year period (2012–2022), total 12790 patients who underwent compression ultrasonography examinations were consecutively included, 1519 (11.9%) LEDVT events occurred....
Abstract Werner syndrome ATP-dependent helicase (WRN) is a member of RecQ involved in DNA replication and repair identified as synthetic lethal target microsatellite instability-high (MSI-H) tumors. MSI-H feature has been found variety tumor types including colorectal, gastric endometrial cancers. The clinical benefits immune checkpoint inhibitor (ICI) such anti-PD-1 or anti-PD-L1 antibodies on cancers have well documented; however, nearly 20-50% these cancer patients are intrinsically...
Objective To develop a probability model of matching into US ophthalmology residency program using San Francisco Matching Program (SF Match) data. Design Retrospective data analysis de-identified application and Participants Registrants for the 2013, 2014, 2015 matches conducted by SF Match. Methods Descriptive statistics candidates, comparison continuous categorical variables between matched nonmatched linear regression modeling were performed. A recursive partitioning method was used to...