Jason M. Devgun
- Poisoning and overdose treatments
- Opioid Use Disorder Treatment
- Pharmaceutical Practices and Patient Outcomes
- Venomous Animal Envenomation and Studies
- Anesthesia and Sedative Agents
- Drug-Induced Hepatotoxicity and Protection
- Supramolecular Self-Assembly in Materials
- Animal Ecology and Behavior Studies
- RNA Interference and Gene Delivery
- Plant-based Medicinal Research
- Diabetes Management and Research
- Pharmacological Effects and Toxicity Studies
- Pain Management and Opioid Use
- Pharmacovigilance and Adverse Drug Reactions
- COVID-19 Clinical Research Studies
- Metabolism, Diabetes, and Cancer
- Rabies epidemiology and control
- Insect and Pesticide Research
- Epilepsy research and treatment
- Animal testing and alternatives
- Forensic Toxicology and Drug Analysis
- Polydiacetylene-based materials and applications
- Diabetes Treatment and Management
- Silk-based biomaterials and applications
- Immunotoxicology and immune responses
Washington University in St. Louis
2020-2023
University of Colorado Denver
2020-2021
Molecular Biology Consortium
2019
Toxikon (United States)
2019
University of Chicago
2009-2011
Abbott (United States)
2011
The rapid spread and mortality associated with COVID-19 emphasized a need for surveillance system development to identify adverse events (AEs) emerging therapeutics. Bradycardia is remdesivir infusion-associated AE listed in the US Food Drug Administration-approved prescribing information.To evaluate magnitude duration of bradycardic following administration.A multicenter cohort study patients recorded heart rate less than 60 beats per minute within 24 hours after administration dose was...
One of the advantages materials produced by self-assembly is that in principle they can be formed any given container to produce predetermined shapes and sizes. Here, we developed a method for triggering peptide within aqueous phase water-in-oil emulsions spherical microgels composed fibrillized peptides. Size control over was achieved specification blade type, speed, additional shear steps emulsion process. Microgels constructed this way could then embedded other self-assembled matrices...
Objective: To describe a large regional poison center's experience managing an outbreak of long-acting anticoagulant rodenticide (LAAR) poisoning associated with synthetic cannabinoid (SC) use.Methods: This is retrospective review exposures reported to the Illinois Poison Center between March 10 and August 1, 2018. All cases coded as exposure Δ9-tetrahydrocannabinol homologs were identified. Patients suspected SC use, positive LAAR testing, coagulopathy (signs or symptoms bleeding...
Introduction Patients with opioid use disorder may have difficulty transitioning from full-agonist opioids to sublingual buprenorphine due the risk of precipitated withdrawal. Novel strategies been developed facilitate this transition, including micro-dosing transdermal buprenorphine. We began using a transition strategy at our hospital in 2019.Methods performed retrospective observational cohort study patients treated (prescribed or recreational) while hospitalized between January 2019 and...